Androscoggin Mill Block

The Maine Supply Company Building is an historic commercial building at 415–417 Lisbon Street in Lewiston, Maine. Built in 1911, this Renaissance Revival building is the best-preserved local work of Miller & Mayo, and is also notable as housing the first known automotive service center in the state. The building was listed on the National Register of Historic Places in 1986.

The Lord Block is a historic commercial building in downtown Lewiston, Maine. Built in 1865, it is one of downtown Lewiston's oldest commercial buildings, and a reminder of the city's early commercial character. The building was listed on the National Register of Historic Places in 1986.

Trinity Episcopal Church is an historic church building at 247 Bates Street in Lewiston, Maine. It is a modestly sized yet handsomely decorated Gothic Revival building, designed by C.C. Haight of New York City and completed in 1882. The building was listed on the National Register of Historic Places in 1978.

The Lower Lisbon Street Historic District encompasses part of the earliest commercial center of Lewiston, Maine. Located on the west side of Lisbon Street, the city's main commercial area, between Cedar and Chestnut Streets are a collection of commercial buildings representing a cross section of architectural styles, built between 1850 and 1950. When the historic district was listed on the National Register of Historic Places in 1985, it included 18 buildings. Eleven of these have since been demolished, and one has a significantly altered facade.

The Second Callahan Block is an historic commercial building at 282 Lisbon Street in downtown Lewiston, Maine. Built in 1909 to a design by Coombs & Gibbs, it was part of a major development by brothers Timothy and Eugene Callahan. It was added to the National Register of Historic Places in 1986. Although initially developed as a commercial property, it is presently used as housing.

The First Callahan Building is an historic commercial and residential building at 276 Lisbon Street in Lewiston, Maine. Built in 1892 to a design by noted local architect George M. Coombs, the Renaissance Reviva brick building was part of a major development on the city's main commercial street by the Callahan brothers, owners of a local gentleman's furnishings store. The building was listed on the National Register of Historic Places in 1986.

The College Block/Lisbon Block is an historic commercial and civic building in Lewiston, Maine, United States. Built in 1855-56, it is the oldest surviving building in the city of the Franklin Company, the city's major early developer. The building has house many local civic groups, and served as Lewiston's town hall prior to its incorporation as a city in 1863. It was listed on the National Register of Historic Places in 1986.

The Agora Grand Event Center is a large event venue in Lewiston, Maine. It is also the second-tallest building in the state. The Agora Grand was created by renovating the former St. Patrick's Church, a Roman Catholic church whose cornerstone was laid on July 24, 1887, by the Right Reverend Bishop Healy and last Mass was held in October 2009. At 220 feet to its taller spire, it is the second-tallest building in Maine, based on the definition of "height to architectural top" by the Council on Tall Buildings and Urban Habitat.It was purchased in March 2014, by developer Andrew Knight, who opened the Agora Grand in May 2016. Knight received an award from the Lewiston Historic Preservation Board for his work in reviving the building; his wedding was the first held at the renovated building.In 2014, Knight converted the former St. Patrick's Church Rectory, also known as the Albert Kelsey Mansion, into a boutique hotel. The former church contains a mortuary chapel and basement crypt in which the church's original builder and priest, Monsignor Thomas Wallace, was buried from 1906 to 2007, when his body was exhumed and moved to Mt. Hope Cemetery. In 2015, Knight converted the former crypt into a novelty annex of the Inn at the Agora, purportedly the world's first "crypt hotel room."

Lewiston City Hall is located at 27 Pine Street (corner of Pine and Park Streets) in downtown Lewiston, Maine. Built in 1892, to a design by John Calvin Spofford, it is a distinctive regional example of Baroque Revival architecture. It is the city's second city hall, the first succumbing to fire in 1890. The building was listed on the National Register of Historic Places in 1976.

The Lewiston Mills and Water Power System Historic District encompasses the major 19th-century mill complexes and associated water power systems in Lewiston, Maine. Developed beginning in 1850, Lewiston's canals and mills were the largest textile mill complex in the state, and one of the best-preserved mature large-scale expressions of the Lowell system of cotton textile manufacturing, perfected at Waltham and Lowell, Massachusetts earlier in the 19th century. The district includes a series power canals and mill complexes developed over a 100-year period, along with mill worker housing and transportation infrastructure. It was listed on the National Register of Historic Places in 2015.

The Savings Bank Block is an historic commercial building at 215 Lisbon Street in downtown Lewiston, Maine. Built in 1870, it is a fine local example of commercial Second Empire architecture, and is representative of the city's early development as an industrial center. It was added to the National Register of Historic Places in 1978.

The Atkinson Building is an historic commercial building at 220 Lisbon Street in Lewiston, Maine, United States. Erected in 1892, the six-story Romanesque style building was the tallest in the city at the time, and is still an imposing presence in the city's central business district. It was designed by Auburn architect Elmer I. Thomas to harmonize with the adjacent Lewiston City Hall (built 1890-92), and is one of its finest Victorian commercial buildings. It was listed on the National Register of Historic Places in 1983.