The Oaks Mall

WRUF (850 kHz) is an AM radio station that operates from the University of Florida's main campus in Gainesville, broadcasting at 850 kHz. WRUF is a sports station that covers University of Florida athletics. Unlike its public sister stations, WUFT TV and WUFT-FM, WRUF is a commercial station and, despite being state-run, is run no differently from privately owned commercial stations. The station signed on in October 1928 and is the fifth-oldest station in the state. WRUF featured a mixture of local and syndicated programs, including Jim Bohannon, Dr. Joy Browne, Larry King Live and Sporting News Radio, plus religious programming on Sunday mornings, including Bill Gaither, The Director of Programming is Rob Harder, Assistant Program Director/Brand Manager is Seth Harp and the Sports Director is Steve Russell. WRUF's sports news departments, staffed almost entirely by School of Journalism students, are fairly large for a station of its size; by at least one account it has the largest local radio news department in Florida. A WRUF microphone used by UF alumnus Red Barber during the 1930s is part of the National Baseball Hall of Fame and Museum's collection. It has been displayed in the museum's "Scribes and Mikemen" exhibit and from 2002 to 2006 it was a part of the "Baseball as America" traveling exhibition. In 2010, WRUF changed their format from news and talk (previously in existence since 1993 and known as Newsradio AM 850 WRUF) to sports (Sportsradio 850) and on June 29, 2012, WRUF received the ESPN Radio affiliation.The station is an affiliate of all three of the city of Tampa's major professional sports teams: the Tampa Bay Rays of Major League Baseball, the Tampa Bay Lightning of the National Hockey League, and since 2020, the Tampa Bay Buccaneers of the National Football League. It is the flagship station for the Florida Gators football, basketball, baseball, women's basketball, lacrosse, soccer and volleyball. On August 19, 2015, WRUF began simulcasting on FM translator W237EJ 95.3 FM in Gainesville. It exists mainly to fill in the gaps because Tower #3 of their directional AM array failed in 2016, and the FCC granted permission to operate non-directionally after sunset at 25% of licensed power. Shortly afterward, the station changed its branding from "ESPN 850" to "ESPN 95.3," after the translator. On December 1, 2016, WRUF switched its FM translator from W237EJ 95.3 FM Gainesville (now simulcasting WUFT-FMHD3 as CHR-formatted GHQ) to W251CG 98.1 FM Gainesville.

Liberty Hill Schoolhouse in Gainesville, Florida is a one-room schoolhouse built in 1892 to serve African-American children. It replaced a previous Liberty Hill School that was in operation by about 1869, and it operated until 1952. The school served students from the community of Rutledge.It is 24.5 feet (7.5 m) by 30.5 feet (9.3 m). There were no lights in the building and drinking water was brought in.It was listed on the National Register of Historic Places on August 28, 2003.

F. W. Buchholz High School (commonly referred to as Buchholz (pronounced ) or BHS) is a high school in Gainesville, Florida, United States. Buchholz is one of seven high schools in Alachua County. Opened in January 1971, it is the largest public high school in Gainesville, with 2,241 students in 2020. The Buchholz Math Team was dubbed "America's Greatest Math Team" by The Wall Street Journal in 2022, when Buchholz won first place for the 14th time in the annually held national Mu Alpha Theta math competition.

Rutledge, Florida is an unincorporated community in central Alachua County, Florida. The community was established for formerly enslaved persons during Reconstruction by the Freedmen's Bureau. The First Morning Star Missionary Baptist Church and the Greater Liberty Hill United Methodist Church, both founded in the 19th century, continue to serve the community. The Greater Liberty Hill church is the site of the Liberty Hill Schoolhouse, which is on the National Register of Historic Places. The Rutledge Community Cemetery, formerly called Union Cemetery of Rutledge, is under the stewardship of the Second Morning Star Missionary Baptist Church. The center of the community was located about five miles west of Gainesville, Florida in the 19th century. As of 2021 it extends from just west of the Gainesville city limits to I-75. A post office was established in 1886, and closed in 1905. In 1888 the community had three stores and a boarding house. It was on the planned route of the Gainesville, Tallahassee and Western Railroad, which was never built.

WRBD (1230 AM) is a commercial radio station in Gainesville, Florida, broadcasting to the Gainesville-Ocala, Florida area.

LifeSouth Community Blood Centers is a not-for-profit blood bank incorporated in Florida. LifeSouth is headquartered in Gainesville, Florida, and serves over 125 hospitals in Florida, Georgia and Alabama. It has formerly been known as Civitan Regional Blood Centers.

Oak Hall School is a private school in Gainesville, Florida, that was founded in 1970 as a segregation academy.

Fort Clarke was an unincorporated community in central Alachua County. The fort established was by the US Army during the Second Seminole War. A historical marker commemorates the fort, which was abandoned by the US Army in 1840. In 1841, 16 citizens voted at Fort Clarke on adopting a proposed constitution for Florida. In May 1845, the community was a precinct at which seven residents voted in the election of the state governor and legislators, and the representative to the US House of Representatives, after Florida was admitted to the union as a state. A post office was established in 1846 and closed in 1858. In 1883, John Bevill, who was described as the model farmer of Alachua County, had over 1,000 acres (400 ha) in cultivation at Fort Clarke. Two churches, the Fort Clarke United Methodist Church and the Greater Fort Clarke Missionary Baptist Church, are currently located in the vicinity of the former site of the fort. The site is now part of the urbanized area west of Gainesville.

Santa Fe College is a public college based in Gainesville, Florida, with satellite campuses in Alachua and Bradford counties. It is part of the Florida College System. It was established in 1965 as Santa Fe Junior College by the Florida Legislature and began offering classes in September 1966. As of Fall 2020, the school had an enrollment of 12,607 students, and offers associate and baccalaureate degree programs.

WYKS (Kiss 105.3) is a commercial radio stations operating in Gainesville, Florida, broadcasting to the Gainesville-Ocala, Florida area on 105.3 FM. The station's format is Contemporary Hit Radio and Top 40 music, and the station has broadcast with this format and call sign since 1981.

The Santa Fe College Teaching Zoo is a 10-acre (4.0 ha) zoo in Gainesville, Florida. Located on Santa Fe College's main campus, it is the only college zookeeper training facility in the United States. Since 2000, the zoo has been accredited by the Association of Zoos and Aquariums (AZA). Guided tours led by students in the program are available at the teaching zoo if scheduled ahead of time; visitors may also take a self-guided tours.

Mildred's Big City Food is a restaurant in Gainesville, Florida.