Laboratory for Laser Energetics

The University of Rochester Medical Center (URMC), now known as UR Medicine, is located in Rochester, New York, is one of the main campuses of the University of Rochester and comprises the university's primary medical education, research and patient care facilities.

Strong Memorial Hospital (SMH) is an 886-bed medical facility, part of the University of Rochester Medical Center complex (abbreviated URMC), in Rochester, New York, United States. Opened in 1926, it is a major provider of both in-patient and out-patient medical services. Attached to Strong is the 190-bed Golisano Children's Hospital, which serves infants, children, teens, and young adults aged 0–21. SMH is owned and operated by the University of Rochester and serves as its primary teaching hospital. It offers programs toward medical, dental, or graduate degrees through the School of Medicine and Dentistry. The hospital anchors the University's health care delivery network in the Rochester area. It serves as a primary community hospital and a regional trauma center for the Rochester area. Also part of the network are Golisano Children's Hospital, and URMC affiliate Highland Hospital.SMH offers care in 40 different specialties and is ranked as one of "America's Best Hospitals" by U.S. News & World Report, and has won the Consumer Choice Award for the best hospital in the area for 12 consecutive years. Strong has signature programs in cardiac care, cancer care, neurology, orthopedics and pediatrics. As an affiliated academic research hospital, patients have access to the latest treatments. Strong also provides emergency medical services. SMH is a teaching hospital and patients may interact with faculty, residents, fellows, interns and/or medical students.

University of Rochester-Golisano Children's Hospital (GCH) formerly Children's Hospital at Strong, is a nationally ranked, freestanding acute care children's hospital in Rochester, New York. It is affiliated with the University of Rochester School of Medicine and Dentistry. The hospital features all private rooms that consist of 168 pediatric beds. The hospital provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout the region. The hospital also sometimes treats adults that require pediatric care. The hospital shares the rooftop helipad for the attached Strong Memorial Hospital and is an ACS verified level I pediatric trauma center, one of the only ones in the region. The hospital features a regional pediatric intensive-care unit and an American Academy of Pediatrics verified level IV neonatal intensive care unit. GCH also offers one of the country's few Ronald McDonald Houses that is located within a hospital.

Monroe Community Hospital is a chronic-care center in Rochester that is operated by Monroe County. They also have a Skilled Nursing Facility

Simon Business School (formerly known as the William E. Simon Graduate School of Business Administration) is the business school of the University of Rochester. It is located on the university's River Campus in Rochester, New York. It was renamed after William E. Simon (1927–2000), the 63rd United States Secretary of the Treasury, in 1986. The school's present dean is Sevin Yeltekin. Simon Business School offers full-time, part-time, and executive (based in either Rochester or Switzerland) Master of Business Administration (MBA) programs, as well as Master of Science (MS) programs. The school is home to substantial academic research enterprises and a PhD program in several business disciplines.

Eastman Institute for Oral Health of University of Rochester is a school of dentistry located at the University of Rochester Medical Center in Rochester, New York, United States. Unlike other dental schools in the United States, it does not have an undergraduate dental program. It is affiliated with Strong Memorial Hospital.The institution records over 180,000 patient visits a year and receives over $9 million in research funding as a location for oral health research in North America. Its programs receive over 1,200 applications every year for 40 positions, resulting in an acceptance rate of 3.3%. In 2011, it underwent a $5.9 million renovation. The school has ranked within the top 10 of National Institutes of Health (NIH)/National Institute of Dental and Craniofacial Research (NIDCR) research funding to dental institutions several times, including ranking seventh in 2020. In the year 2020, the Eastman Institute for Oral Health published over 150 peer-reviewed research publications.

Arvine Heights Historic District is a national historic district located at Rochester, Monroe County, New York. The district encompasses 61 contributing buildings (37 residences) in an exclusively residential section of Rochester. The district developed between about 1920 and 1942, and includes residential buildings in a variety of architectural styles including Colonial Revival, Tudor Revival, and Bungalow / American Craftsman. The dwellings reflect modest designs directed toward a middle-class clientele in a newly developing area of Rochester's Nineteenth Ward.It was listed on the National Register of Historic Places in 2015.

The Warner School of Education and Human Development is a graduate school of education that prepares practitioners and scholars in the areas of teacher education, counselling, K-12 school leadership, higher education, human development, and educational policy. The school is part of the University of Rochester and located in Rochester, New York.

The University of Rochester is a private research university in Rochester, New York, United States. It enrolls approximately 6,800 undergraduates and 5,000 graduate students. It was founded in 1850 and moved into its current campus, next to the Genesee River in 1955. With approximately 30,000 full-time employees, the university is the largest private employer in Upstate New York and the 7th largest in all of New York State.Rochester offers 160 undergraduate and 30 graduate programs across seven schools spread throughout five campuses. The College of Arts, Sciences, and Engineering is the largest school, which includes the Hajim School of Engineering and Applied Sciences, and houses some of the college's departments and divisions. The Institute of Optics was founded in 1929 and is regarded among the premier optics programs in the world. The Departments of Political Science and Economics have influenced positivist social science since the 1960s. The Rossell Hope Robbins Library serves as the university's resource for Old and Middle English texts and expertise. The school is noted for its Rochester curriculum, which has only required one course and requires a breadth of study across fields.The university is also home to Rochester's Laboratory for Laser Energetics, a national laboratory supported by the US Department of Energy that is the largest university-based US Department of Energy program in the nation The university is classified among "R1: Doctoral Universities – Very high research activity" and is a member of the Association of American Universities, which emphasizes academic research.Rochester alumni, faculty, and affiliates include recipients of 13 Nobel Prizes, 9 National Medals of Science, 13 Pulitzer Prizes, 45 Grammy Awards, and 20 Guggenheim Fellowships.

The University of Rochester Arboretum is an arboretum located across the River Campus of the University of Rochester, 612 Wilson Boulevard, Rochester, New York. The River Campus is located beside the Genesee River on a site previously owned by the Oak Hill Country Club. Famed landscape architect Frederick Law Olmsted, Sr. had designed a "River Walk" of oak trees along the river; and after the university purchased the site in 1923, his son Frederick Law Olmsted Jr. served as landscape designer and consultant to the campus architects. In 1999 certain areas of the campus were designated as the arboretum. The River Walk was recently sold to the City of Rochester as public parkland along the river corridor. In a 1 km (¾ mile) area between Elmwood Avenue and Intercampus Drive are 197 oak trees representing 15 species. Trees in the arboretum proper currently include: American Beech (Fagus grandifolia), Amur corktree (Phellodendron amurense), Baldcypress (Taxodium distichum), Black Gum (Nyssa sylvatica), Dawn Redwood (Metasequoia glyptostroboides), Goldenraintree (Koelreuteria paniculata), Hally Jolivette cherry (Prunus 'Hally Jolivette'), Japanese Pagoda Tree (Styphnolobium japonicum), Japanese Zelkova (Zelkova serrata), Katsura Tree (Cercidiphyllum japonicum), Kentucky Coffeetree (Gymnocladus dioicus), Kanzan cherry (Prunus serrulata 'Kanzan'), Late Lilac (Syringa villosa), Miyabe's Maple (Acer miyabei), Osage-orange (Maclura pomifera), Paperbark Maple (Acer griseum), Northern Red Oak (Quercus rubra), Scarlet Oak (Quercus coccinea), Wych Elm (Ulmus glabra), Shadblow serviceberry (Amelanchier canadensis), Sweetgum (Liquidambar styraciflua) and Tulip-tree (Liriodendron tulipifera). Although not located on the River Campus, the university grounds also contain two state champion trees, a weeping willow and a Ponderosa Pine. They are the largest known examples in the New York state.

Rush Rhees Library is the main academic library of the University of Rochester in Rochester, New York. It is one of the most visible and recognizable landmarks on the university's River Campus. Construction began in 1927 with the other original River Campus buildings and the library was dedicated in 1930. It is named after Benjamin Rush Rhees, the university's third president. A major addition was added in 1970, which now houses the main computer lab, additional stacks and office space. Rush Rhees is the flagship of the River Campus Libraries System, which holds about 3 million volumes. The library featured an elevator completely original from 1930 until 2021 when it received a full modernization.

Genesee Valley Park, originally named "South Park", is located in the south side of Rochester, New York along the shores of the Genesee River. The New York State Barge Canal (the currently in-use portion of the Erie Canal) crosses the Genesee River within the park. The University of Rochester is located near the park's north entrance.