9–10th & Locust station

William Strickland Row was a set of seven historic rowhouses, four of which survive. The row was designated a national historic district which is located in the Washington Square West neighborhood of Philadelphia, Pennsylvania. The brick houses were built about 1815, and measure between 16 feet, 6 inches, and 20 feet wide and 35 feet deep. They are each designed in the typical Philadelphia rowhouse plan of the period with front building, piazza, and back building. The exhibit Greek Revival style design details. Noted Philadelphia architect William Strickland (1788–1854) resided at 219 S. 9th Street from 1823 to 1829.The row was added to the National Register of Historic Places in 1977.

Jefferson Hospital for Neuroscience is a hospital in Center City, Philadelphia, affiliated with Thomas Jefferson University and Thomas Jefferson University Hospital in Philadelphia. The Hospital focuses on treating brain-related diseases and disorders. It is the only hospital of its kind in the Philadelphia area. The Hospital annually treats the largest combined volume of brain tumors, spinal cord injury, aneurysms and AVMs in the Philadelphia region.Jefferson Hospital for Neuroscience was the first in the Delaware Valley to offer a number of technologies including: Fractionated stereotactic radiosurgery (also known as stereotactic radiotherapy) Gamma Knife® Shaped Beam Surgery™ Minimally invasive neurosurgery utilizing a robotically controlled microscope NeuRx DPS™, an FDA-approved device that helps individuals with certain types of spinal cord injuries breathe on their own againThe hospital also established Jefferson Expert Teleconsulting (JET) – the first technology of its kind in the region. It is a university-based high-tech mobile robotic teleconsulting system.

The Musical Fund Hall in Philadelphia is a landmark building of both architectural and historic significance, noted especially for the illustrious persons who have spoken or performed there. It is perhaps best remembered as the setting for the first Republican National Convention, June 17–19, 1856. It was listed on the National Register of Historic Places in 1971.

The Walnut Street Theatre, founded in 1808 at 825 Walnut Street, on the corner of S. 9th Street in the Washington Square West neighborhood of Philadelphia, is the oldest operating theatre in the United States. The venue is operated by the Walnut Street Theatre Company, a non-profit organization, and has three stages: the Mainstage, for the company's primary and larger productions, the Independence Studio on 3, a studio located on the building's third floor for smaller productions, and the Studio 5 on the fifth floor, which is rented out for independent productions. In May 2019, the Walnut Street Theatre announced a major expansion, to begin in 2020. In March 2020, the expansion was postponed six weeks from its initial groundbreaking due to the COVID-19 pandemic.

Mikveh Israel Cemetery is the oldest Jewish cemetery in Philadelphia, Pennsylvania, giving evidence of a settled community as early as 1740. A number of outstanding patriots, pioneers, and other notables of the Jewish faith who made important contributions to the history and freedom of America during the Colonial and Revolutionary period were interred here, and for this reason, in 1959, by an act of Congress, the burial ground was designated as a unit of the Independence National Historical Park, while continuing to be maintained by the sponsoring Congregation Mikveh Israel. The cemetery was certified by the Philadelphia Historical Commission, and in 1971, it was listed on the National Register of Historic Places.The site is 60 by 80 feet (18 m × 24 m), less than 0.2 acres (810 m2) in size, and is located in the Washington Square West neighborhood, in the center city section of Philadelphia, about 1⁄4 mi west and 1⁄4 mi south of Independence Hall.

The Reynolds-Morris House is a historic house at 225 South 8th Street in the Washington Square West neighborhood of Philadelphia, Pennsylvania. Built in 1786–87 by John and William Reynolds, it is a well-preserved example of a Philadelphia Georgian townhouse. It was designated a National Historic Landmark in 1967, and is currently operated as a hotel.

Samuel Gross (1897) is a bronze statue by sculptor Alexander Stirling Calder, created as a monument to the American surgeon Dr. Samuel D. Gross (1805–1884). It was commissioned for and originally installed at the Army Medical School in Washington, D.C., on what is now the National Mall. In April 1970, it was relocated to the campus of Jefferson Medical College (now Thomas Jefferson University) in Philadelphia, Pennsylvania. It currently stands on the Sidney and Ethal Lubert Plaza, within the square bordered by 10th, Walnut, 11th and Locust Streets.

The Penn Club is a private social club in Philadelphia. It was organized on March 18, 1875, with a mission to heighten awareness of arts and culture at the time of the Centennial Exposition.

Portico Row is a set of 16 historic rowhouses located in the Washington Square West neighborhood of Philadelphia, Pennsylvania. The brick houses were built between 1831 and 1832, and designed by Philadelphia architect Thomas Ustick Walter (1804–1887). They have the typical Philadelphia rowhouse plan with front building, piazza, and back building and are in the Greek Revival style. Each of the eight mirror-image pairs shared a common entrance portico supported by Ionic order columns.It was added to the National Register of Historic Places in 1977.

The St. James is a luxury residential skyscraper in Washington Square West, Philadelphia, Pennsylvania, United States. The 498 feet (152 m), 45-story high-rise stands along Walnut Street and Washington Square and is the 15th tallest building in Philadelphia. The Chicago-style, glass-and-concrete skyscraper incorporated into its design several historic 19th-century buildings that lined Walnut Street. These buildings included three Federal-style rowhouses built in 1807 called York Row and the Italianate-style former headquarters of the Philadelphia Savings Fund Society, built in 1868–1869. After lying vacant and neglected for years, the only part of York Row preserved were the rowhouses' facades. Only a back portion of the Philadelphia Savings Fund Society building was demolished, the rest being incorporated as retail and office space. Developer P&A Associates first attempted to develop the site in 1995, but was delayed because of a lack of investor confidence in the project. When the Philadelphia residential market improved in the late 1990s, St. James Associates Joint Venture, a joint venture of P&A Associates and others, began construction in November 2001. The high-rise building, completed in 2004, features 306 units, with each but the studio apartments having a private balcony. Its amenities include a 60 feet (18 m) swimming pool, a private courtyard, and a nine-story parking garage that makes up the base of the building.

Pennsylvania Hospital is a private, non-profit, 515-bed teaching hospital located in Center City Philadelphia and is part of the University of Pennsylvania Health System. Founded on May 11, 1751, by Benjamin Franklin and Dr. Thomas Bond, Pennsylvania Hospital is one of the earliest established public hospitals in the United States. It is also home to America's first surgical amphitheatre and its first medical library. The hospital's main building, dating to 1756, is a National Historic Landmark.

Thomas Jefferson University Hospital is the flagship hospital of Jefferson Health, a multi-state non-profit health system based in Philadelphia. The hospital serves as the teaching hospital for Thomas Jefferson University.