Russell Company Upper Mill

The Sanseer Mill is a historic 19th-century mill at 282 Main Street Extension in Middletown, Connecticut. It was added to the United States National Register of Historic Places in 1986.

The Middletown Woodrow Wilson High School is a former high school, now used as residential apartments, located at 339 Hunting Hill Avenue, Middletown, Connecticut. Built in 1931, it was the city's first unified high school, a role it served until 1958. It then served as a junior high school before being adapted to its present residential use. The building was listed on the National Register of Historic Places in 1986.

Connecticut Valley Hospital in Middletown, Connecticut, is a public hospital operated by the state of Connecticut to treat people with mental illness. It was historically known as Connecticut General Hospital for the Insane. It is a 100-acre (40 ha) historic district that was listed on the National Register of Historic Places in 1985.The historic district includes late 19th and 20th century revival and late Victorian architecture. When listed on the National Register, the district included 27 contributing buildings. Also included were 25 non-contributing buildings.

Pameacha Creek is a stream in Middletown, Connecticut.

Mansfield Club Grounds, also known as Mansfield Park and Fort Hill Grounds, was a baseball ballpark located in Middletown, Connecticut. The ballpark was home to the Middletown Mansfields baseball club during the 1872 season, from May 2nd until July 4th. Like the team, it was named after Civil War General Joseph K. Mansfield. The land for the ballpark, which overlooked Middletown, the Connecticut River, and the Valley Railroad, was donated in 1871 by Dewitt Clinton Sage who owned a nearby brick factory. The former site is now a residential development.

The Wilcox, Crittenden Mill, also known as Wilcox, Crittenden Mill Historic District, is a 17-acre (6.9 ha) property in Middletown, Connecticut that was listed on the National Register of Historic Places in 1986. It was the location of the Wilcox, Crittenden company, a marine hardware firm. The historic district listing included four contributing buildings and three other contributing sites.

Middlesex Hospital is a non-profit, acute care community hospital in Middletown, Connecticut. Its service area includes Middlesex County, Connecticut, and the lower Connecticut River Valley region. In 2015 Middlesex became the first hospital in Connecticut to join the Mayo Clinic Care Network.

Pameacha Pond is a body of water in Middletown, Connecticut, located along South Main Street (Route 17). The pond exists behind a roughly 10.5 foot high by 83 foot long rough stone dam long.

St. Mary of Czestochowa Parish (Polish: Parafia św. Marii Częstochowskiej w Middletown) is a Catholic church parish in Middletown, Connecticut that was founded for Polish immigrants. The St. Mary of Czestochowa Church is a church building at 79 South Main Street in Middletown. The parish was founded in 1903. It is one of the Polish-American Roman Catholic parishes in New England in the Roman Catholic Diocese of Norwich.

The Middletown Alms House is a historic building at 53 Warwick Street in Middletown, Connecticut, constructed in 1813–1814. It was originally used as a poorhouse and is the oldest surviving building built for housing the poor in Connecticut, as well as one of the oldest such in the United States.: 6  One of the largest structures of the Federal period in Middletown, it was listed on the National Register of Historic Places in 1982.

Located in Middletown, Connecticut, the Middletown South Green Historic District was created to preserved the historic character of the city's South Green and the historic buildings that surround it. It is a 90-acre (36 ha) historic district that includes a concentration of predominantly residential high-quality architecture from the late 19th century. It was listed on the National Register of Historic Places in 1975.

The Metro South Historic District encompasses a portion of the downtown area of Middletown, Connecticut. Extending south from Main and College Streets for two blocks, this area was developed in the 19th century, and contains a diversity of well-preserved architecture from that period, some with association to locally important individuals. It was listed on the National Register of Historic Places in 1980.