Statue of King Philip IV of Spain (Bernini)

The Basilica of Saint Mary Major (Italian: Basilica di Santa Maria Maggiore, Italian pronunciation: [ˈsanta maˈriːa madˈdʒoːre]; Latin: Basilica Sanctae Mariae Maioris), or church of Santa Maria Maggiore, is a Major papal basilica as well as one of the Seven Pilgrim Churches of Rome and the largest Catholic Marian church in Rome, Italy. The basilica enshrines the venerated image of Salus Populi Romani, depicting the Blessed Virgin Mary as the health and protectress of the Roman people, which was granted a Canonical coronation by Pope Gregory XVI on 15 August 1838 accompanied by his Papal bull Cælestis Regina. Pursuant to the Lateran Treaty of 1929 between the Holy See and Italy, the Basilica is within Italian territory and not the territory of the Vatican City State. However, the Holy See fully owns the Basilica, and Italy is legally obligated to recognize its full ownership thereof and to concede to it "the immunity granted by International Law to the headquarters of the diplomatic agents of foreign States." In other words, the complex of buildings has a status somewhat similar to a foreign embassy.

The Pontifical Oriental Institute, also known as the Orientale, is a Catholic institution of higher education located in Rome and focusing on Eastern Christianity. The plan of creating a school of higher learning for Eastern Christianity had been on the agenda of the Catholic Church since at least Pope Leo XIII, but it was only realized in 1917 by Pope Benedict XV. The Orientale forms part of the consortium of the Pontifical Gregorian University (founded in 1551) and the Pontifical Biblical Institute (founded in 1909), both in Rome. All three institutions are run by the Society of Jesus (Jesuits). While the Orientale depends on the Holy See, its management is entrusted to the Society of Jesus. Its chancellor is the Prefect of the Congregation for the Eastern Churches and its vice-chancellor is the superior general of the Society of Jesus, while the Congregation for Catholic Education is the dicastery competent for approving the academic programmes of the Orientale. Each year, another approximately 400 scholars visit the library for research purposes.

The Bust of Giovanni Battisti Santoni is a sculptural portrait by the Italian artist Gian Lorenzo Bernini. Believed to be one of the artist's earliest works, the bust forms part of a tomb for Santoni, who was majordomo to Pope Sixtus V from 1590 to 1592. The work was executed sometime between 1613 and 1616, although some have dated the work as early as 1609 (when Bernini was ten years old), including Filippo Baldinucci. The work remains in its original setting in the church of Santa Prassede in Rome.

The Basilica of Saint Praxedes (Latin: Basilica Sanctae Praxedis, Italian: Basilica di Santa Prassede all’Esquillino), commonly known in Italian as Santa Prassede, is an early medieval titular church and minor basilica located near the papal basilica of Saint Mary Major, on Via di Santa Prassede, 9/a in rione Monti of Rome, Italy. The current Cardinal Priest of Titulus Sancta Praxedis is Paul Poupard. Dedicated to the second-century saint Praxedes, who with her sister Pudentiana, was said to have provided comfort and care to Christians persecuted in the Roman Empire.

The Basilica of Junius Bassus (basilica Iunii Bassi) was a civil basilica on the Esquiline Hill in Rome, on a site now occupied by the Seminario Pontificio di Studi Orientali, in via Napoleone III, 3. It is best known for its examples of opus sectile work.

Sant'Antonio abate all’Esquilino (Saint Anthony Abbot on the Esquiline) is a church in Rome, located near the Basilica of Santa Maria Maggiore on via Carlo Alberto in the Esquilino district.

Sant'Andrea Catabarbara was a church in Rome, located on what is now the site of the Pontifical Oriental Institute on Via Napoleone III, in the Esquilino district. It was first called Catabarbara or Cata Barbara Patricia in the eighth century. It was the first devotional church dedicated to Saint Andrew in the city of Rome. Its foundation probably dates to the donation of an aula or hall from the home of Junius Annius Bassus, consul in the year 331, by the Goth general Valila. An inscription from the apse of the church possibly records the donation, though its meaning is uncertain. The church was therefore the result of the transformation from a secular home or house-church into a church, due to the work of Pope Simplicius in the second half of the fifth century. The hall was turned into a monastery to serve the nearby Basilica of Santa Maria Maggiore. It and its rich decoration were demolished to build the Pontifical Oriental Institute in 1930.

The Collegium Russicum (Latin: Pontificium Collegium Russicum Sanctae Theresiae A Iesu Infante; Russian: Папская коллегия Ру́ссикум; English: Pontifical Russian College of Saint Thérèse of the Child Jesus) is a Catholic college in Rome dedicated to studies of the culture and spirituality of Russia. It is located near the Basilica di Santa Maria Maggiore, separated from the Pontifical Oriental Institute by the Church of Saint Anthony, and is known informally as the Russicum.

The Church of Saint Alphonsus Liguori (Chiesa di Sant'Alfonso di Liguori all'Esquilino in Italian) is a rectory church located on the Via Merulana on the Esquiline Hill of central Rome's Vth prefecture, Italy, and a titular church for a Cardinal-priest under the name Santissimo Redentore e Sant'Alfonso in Via Merulana (Holy Redeemer and St. Alfonso).

The Alphonsian Academy (Italian: Accademia Alfonsiana; Latin: Academia Alphonsiana), also commonly known as the Alphonsianum, is a pontifical institution of higher education founded in 1949 by the Redemptorists and located in Rome, Italy. Since 1960, the Academy has specialized in moral theology as a part of the Faculty of Theology of the Pontifical Lateran University. The Academy grants both the licentiate and the doctoral degrees in moral theology.

The Esquiline Hill (; Latin: Collis Esquilinus; Italian: Esquilino [eskwiˈliːno]) is one of the Seven Hills of Rome. Its southernmost cusp is the Oppius (Oppian Hill).

Torre dei Capocci (Engl.: "The Tower of the Capocci") is a tower at San Martino ai Monti square in Rome, Italy.Torre dei Capocci, along with Torre dei Graziani, constitutes a kind of monumental entrance to top of the hill Esquilino. Built by the family of Arcioni in the 12th century, it afterwards went to the Capocci, a noble family from Viterbo. These erected around the tower a number of houses, which no longer exist, but which made the building a sort of citadel. The tower is 36 m (118 ft) high with seven floors, a square base, and windows framed in travertine. The terrace, bordered by a brick parapet, is edged by crenellated battlements on each side, and emerges at the output hopper of the staircase.