Statue of Thomas Brackett Reed

The Adam P. Leighton House is an historic house at 261 Western Promenade in Portland, Maine. Built in 1903, it is a fine local example of Colonial Revival architecture, and is further prominent as home to Adam P. Leighton, who was "considered the father of the American postcard industry", and served as the Mayor of Portland from 1908 to 1909. The house was listed on the National Register of Historic Places in 1982.

Florence House is a 31⁄2 story building in Portland, Maine, United States, named after Florence Young "a social worker who spent more than 20 years working at Preble Street."The building was created to help end homelessness. Florence House is based on the Housing First model, a strategy to help move women from homelessness to a permanent supportive home environment. Florence House can house 50 or more former homeless women. The building includes 25 efficiency apartments, a safe-haven area with 15 semi-private spaces and 10 to 25 emergency shelter beds The $7.9 million facility was completed on April 6, 2009. It was developed by Preble Street and Avesta Housing and received state and federal funding as well as private contributions. The opening in April, 2009 (five years after the project started) was attended by Maine Governor John Baldacci, Shaun Donovan (Secretary of Housing and Urban Development — HUD), Senator Olympia Snowe, Senator Susan Collins, Representative Chellie Pingree, and other dignitaries.

The West End is a downtown neighborhood in Portland, Maine. It is located on the western side of Portland's peninsula primarily on Bramhall Hill and is noted for its architecture and history. The neighborhood is home to many late 19th- and early 20th-century homes and, in 2010, it was called "one of the best preserved Victorian neighborhoods in the country". The Western Promenade, a park laid out in 1836, overlooks the forests and small settlements of Southwestern Maine, along with the distant White Mountains. Other historic structures include 68 High Street, The Gothic House, Brown House, Butler House, Ingraham House, Morrill Mansion and the Minott House. The West End is known for ethnic and socioeconomic diversity; in 1994, it was called one of Portland's 'gay-friendly' neighborhoods.

Bramhall was a mansion in the Bramhall neighborhood of Portland, Maine, United States. Completed in 1858, it was owned by John Bundy Brown, an industrialist. The mansion, which was designed by New York City architect Charles A. Alexander, stood behind today's 147–163 Western Promenade, near which he also built homes for his children. After Brown's death, the mansion, which was the largest residence in Portland, was demolished. The 10 acres (4.0 ha) of land bounded by Bowdoin Street, Pine Street, Vaughan Street and Western Promenade was sold parcel by parcel, and the present neighborhood was built. The area is now part of the Western Promenade Historic District. The building, which had a conservatory on its southern side, was demolished in 1915.

Maine Medical Center (commonly abbreviated to MMC or contracted to Maine Med) is a 700-licensed-bed teaching hospital in Portland, Maine, United States. Affiliated with Tufts University School of Medicine, it is located in the Western Promenade neighborhood. It has a staff of over 9,500. The facility is one of only three Level I Trauma Centers in Northern New England. Founded in 1874, it is the largest hospital in northern New England with 28,000 inpatient visits, about 500,000 outpatient visits, 88,000 emergency visits, and over 27,000 surgeries performed annually. MMC is structured as a non-profit, private corporation governed by volunteer trustees. Maine Medical Center is wholly owned by, and serves as the flagship hospital for, MaineHealth, a non-profit healthcare network servicing Maine and New Hampshire.

The Western Promenade is a historic promenade, an 18.1-acre (7.3 ha) public park and recreation area in the West End neighborhood of Portland, Maine. Developed between 1836 and the early 20th century, it is one Portland's oldest preserved spaces, with landscaping by the Olmsted Brothers, who included it in their master plan for the city's parks. The promenade was listed on the National Register of Historic Places in 1989.

The John Calvin Stevens House is an historic house at 52 Bowdoin Street in the West End neighborhood of Portland, Maine. Built in 1884, it was the home of architect John Calvin Stevens, and was one of Portland's earliest examples of Shingle style architecture. The house was prominently used by Stevens in promotion of the style, and was listed on the National Register of Historic Places in 1973.

The former Maine Central Railroad General Office Building is an historic office building at 222-242 Saint John Street in the Saint John Valley neighborhood of Portland, Maine. Built in stages between 1889 and 1916, it was home to the Maine Central Railroad Company, the state's largest railroad operator. It is also one of the city's largest office buildings, and a fine example of Romanesque Revival architecture. It was listed on the National Register of Historic Places in 1988.

Union Station was a train station in Portland, Maine, which was inoperation between 1888 and 1960. It was demolished in 1961 and is now the site of a strip mall.

St. John Street is a street in Portland, Maine, United States. It runs for around 1.34 miles (2.16 km) from Brighton Avenue (part of Maine State Route 25), in the north, to Valley Street, in the south. It crosses Park Avenue (part of Maine State Route 22) and Congress Street and passes beneath Interstate 295. Both St. John Street and adjacent Valley Street were built upon land occupied by Portland's poor farm. St. John Street is named for St. John Smith (1876–1944), a landowner friend and business partner of industrialist John Bundy Brown. The city's Union Station stood in Railroad Square on St. John Street between 1888 and 1961, when it was demolished and replaced with today's Union Station Plaza strip mall. Beside that location, to the south, is the Maine Central Railroad General Office Building, which was completed in 1916. It is listed on the National Register of Historic Places. A spur of the Portland and Ogdensburg Railway from Union Station crosses Maine Central Railroad's trestle bridge at St. John Street and Park Avenue. The line continues behind Hadlock Field and Fitzpatrick Stadium before ending at Forest Avenue, beside Deering Oaks Park. The Inn at St. John (formerly the Hotel Victoria), which stands at the intersection of St. John Street and Congress Street, has been in operation since 1897. Its location was chosen because of its proximity to Union Station. St. John Street was the home to Portland's first McDonald's. It is still in operation. Portland's Greyhound bus station was formerly located at the intersection of St. John Street and Congress Street. The building, constructed in 1961, closed in 2019, after 32 years of ownership by Greyhound. Buses now depart from the park and ride lot on Marginal Way.

The Maine Eye and Ear Infirmary is a historic medical facility that was located at 794-800 Congress Street in Portland, Maine. Also known as Holt Hall, the structure, designed by John Calvin Stevens, was redeveloped into a residential building in 1997, after standing dormant for nearly 10 years. The Maine Eye and Ear Infirmary was built in 1891. In 1951 the hospital merged with the Children's Hospital and Maine General Hospital to become Maine Medical Center. The facility was added to the National Register of Historic Places in 1986.

The Western Promenade Historic District encompasses a large late 19th- and early 20th-century neighborhood in the West End of Portland, Maine. This area of architecturally distinctive homes was home to three of the city's most prominent architects: Francis H. Fassett, John Calvin Stevens, and Frederick A. Tompson, and was Portland's most fashionable neighborhood in the late 19th century. The district was listed on the National Register of Historic Places in 1984.