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The Commercial Exchange Building, also known as the Collins Manufacturing – Jackson Automobile Company complex, is an industrial building complex located at 2301 E. Michigan Ave. in Jackson, Michigan. The building was built partly in 1895, and was listed on the National Register of Historic Places in 1993. The listing included four contributing buildings.

The Andrew Wilcox House, also known as the Wilcox-Holton House, is a single-family home located at 231 East High Street in Jackson, Michigan. It was listed on the National Register of Historic Places in 1987.

Michigan Center Jr/Sr High School is a public secondary school in Leoni Township, Michigan Center, Michigan, United States.

Henry Ford Allegiance Health is a 475-bed health system in Jackson in the U.S. state of Michigan. Henry Ford Allegiance Health has more than 400 physicians and 3,700 staff members. The health system offers specialized services including a new cancer center and a heart center with a 20-bed cardiac universal bed unit. A new specialty center combines services for patients with brain, spine, neck, joint and bone conditions. The specialty center also includes a new osteoporosis center, balance center and pain management center as well. Other health system features include an emergency department designated as a level II trauma center, urgent care centers, and a pediatric and birthing care. Henry Ford Allegiance Health operates the Henry Ford Allegiance Specialty Hospital (formerly CareLink of Jackson) to provide long-term acute care. The Health System also provides care at family medical centers in Albion, Brooklyn, Grass Lake, Jackson, Leslie, Mason, Onsted and Spring Arbor. Henry Ford Allegiance Radiation Oncology offers cancer care.

Jackson station is a historic Amtrak station in Jackson, Michigan, United States. It is served by three daily Wolverine trains between Chicago and Pontiac and a single daily Amtrak Thruway bus between Toledo, Detroit, Jackson, and East Lansing. The station was added to the National Register of Historic Places in 2002.

Vandercook Lake High School is a high school in Jackson, Michigan, United States. It is the home of the Jayhawk and they compete in the Cascades Conference.

East Jackson Secondary School is a public high school located in southern Mid-Michigan in the eastern part of Jackson County. It currently contains approximately 580 students, ranging from grades 7th through 12th. It is the only secondary school in the East Jackson Community Schools district.

The Otsego Apartments, formerly known as the Otsego Hotel is an apartment building located at 102–106 Francis Street in Jackson, Michigan. The building was listed on the National Register of Historic Places in 2015.

St. Mary Star of the Sea Catholic Church is a parish of the Roman Catholic Church located in downtown Jackson, Michigan, in the Diocese of Lansing. It is dedicated to Our Lady, Star of the Sea. In 2008 it absorbed the congregations of St. Stanislaus Kostka Chapel and the Chapel of Sacred Heart, also in Jackson.

The Michigan Theatre at 124 North Mechanic Street in Jackson, Michigan opened in 1930 and was designed by Maurice Herman Finkel. It was listed on the National Register of Historic Places on May 8, 1980, and is undergoing renovations as of 2005.

The Peoples National Bank Building, also known as the Elaine Apartments, is a former office building located at 101 E. Michigan Ave. in Jackson, Michigan. The building was listed on the National Register of Historic Places in 2014.

Jackson is the only city and county seat of Jackson County in the U.S. state of Michigan. As of the 2020 census, the city population was 31,309. Located along Interstate 94 and U.S. Route 127, it is approximately 40 miles (64 km) west of Ann Arbor and 35 miles (56 km) south of Lansing. Jackson is the core city of the Jackson Metropolitan Statistical Area, which includes all of Jackson County and population of 160,248.Founded in 1829, it was named after President Andrew Jackson. Michigan's first prison, Michigan State Prison (or Jackson State Prison), opened in Jackson in 1838 and remains in operation. For the longest time, the city was known as the "birthplace of the Republican Party" when politicians met in Jackson in 1854 to argue against the expansion of slavery, although the political party now formally recognizes its birthplace as being Ripon, Wisconsin. Nevertheless, the Republican Party's earliest history dates back to Jackson and is commemorated by a plaque in the city's Under the Oaks City Park, which has since been visited by numerous Republican presidents.At the beginning of the twentieth century, Jackson became an early automotive manufacturing center that attracted southerners and immigrants to the city's numerous factories, which saw its population increase significantly.