Detroit Masonic Temple

The American Hotel is a former hotel in Detroit, Michigan, that was built in 1926, located on Temple Street and Cass Avenue, located beside the Detroit Masonic Temple and was originally named the Fort Wayne Hotel. The structure is 11 stories high with 300+ rooms and has been vacant since the early 1990s.

The Cass Park Historic District is a historic district in Midtown Detroit, Michigan, consisting of 25 buildings along the streets of Temple, Ledyard, and 2nd, surrounding Cass Park. It was listed on the National Register of Historic Places in 2005 and designated a city of Detroit historic district in 2016.

The Detroit Institute of Technology was a private four-year technical college in Detroit, Michigan that closed operations in 1981.

The Metropolitan Center for High Technology, formerly S. S. Kresge World Headquarters, is an office building located at 2727 Second Avenue in Midtown Detroit, Michigan. It was listed on the National Register of Historic Places and designated a Michigan State Historic Site in 1979. The office building is now part of Wayne State University and used as a business incubator for startup companies.

Cass Technical High School (simply referred to as Cass Tech) is a magnet high school in Midtown Detroit, Michigan, United States. It was established in 1907 and is part of the Detroit Public Schools Community District. It is named after Lewis Cass.Until 1977, Cass was Detroit's only magnet school and the only non-neighborhood enrollment school in Detroit. It remains one of few magnet schools in Detroit. Entrance is based on test scores and middle school grades. Students are required to choose a curriculum path—roughly equivalent to a college "major" —in the ninth grade. Areas of study include among others arts and communication, business management and marketing, engineering and manufacturing, human services, and science and arts.

The Eddystone Building is a former hotel located in Midtown Detroit, Michigan, at 100-118 Sproat Street. It was listed on the National Register of Historic Places in 2006.

The Park Avenue Hotel was a hotel in the Cass Corridor of Detroit, Michigan. It was listed on the National Register of Historic Places in 2006. It was also known as Salvation Army Harbor Light Center and is not to be confused with Park Avenue House, also once known as Park Avenue Hotel. The building was imploded on July 11, 2015.

The Clay Office and Conference Center is a renovated office complex formerly known as the Clay School. It is located at 453 Martin Luther King, Jr. Boulevard in Midtown Detroit, Michigan. It is the oldest school building in the city of Detroit. It was listed on the National Register of Historic Places and designated a Michigan State Historic Site in 1982.

The Cass–Davenport Historic District is a historic district containing four apartment buildings in Detroit, Michigan, roughly bounded by Cass Avenue, Davenport Street, and Martin Luther King, Jr. Boulevard. The district was listed on the National Register of Historic Places in 1997. The Milner Arms Apartments (originally known as the Hotel Stevenson) abuts, but is not within, the district.

Little Caesars Arena is a multi-purpose arena in Midtown Detroit. Opened on September 5, 2017, the arena, which cost $862.9 million to construct, replaced Joe Louis Arena and The Palace of Auburn Hills as the home of the Detroit Red Wings of the National Hockey League (NHL) and the Detroit Pistons of the National Basketball Association (NBA), respectively. The arena features a unique, clear plastic roofed concourse connecting it to offices and shops surrounding it. It was designed to be the flagship of a new $2.1 billion 650,000-square-foot (60,000 m2) sports and entertainment district, The District Detroit, with mixed-use neighborhoods with new residential and retail outlets located around the Cass Corridor, Ford Field, and Comerica Park. However, this has yet to materialize.

The Midtown Woodward Historic District is a historic district located along Woodward Avenue in Detroit, Michigan. Structures in the district are located between 2951 and 3424 Woodward Avenue, and include structures on the corner of Charlotte Street (14 Charlotte Street) and Peterboro Street (10 and 25 Peterboro Street). The district was admitted to the National Register of Historic Places in 2008.

The First Unitarian Church of Detroit was located at 2870 Woodward Avenue in Midtown Detroit, Michigan. Built between 1889 and 1890, it was listed on the National Register of Historic Places in 1982. It was destroyed by fire on May 10, 2014.