Schroeder-Klein Grocery Company Warehouse

The Bishop's Block, also known as the Bishop's Block Apartments, is a historic building located in Dubuque, Iowa, United States. It was individually listed on the National Register of Historic Places in 1994. It was included as a contributing property in the Old Main Street Historic District in 2015.

Dubuque station was a train station in Dubuque, Iowa. It originally served the Illinois Central Railroad. In 1917, the site was considered for creating a Union station in Dubuque. However, no such plan transpired and each railroad continued to use separate depots. Over the years, the station hosted the Illinois Central's Hawkeye, Iowan, and Land O'Corn trains. Passenger service ceased upon the formation of Amtrak in 1971, but resumed between Chicago and Dubuque in 1974 under the name Black Hawk. Service ceased on September 30, 1981. A proposed revival of the service, since cancelled, was to use the Dubuque Intermodal Transportation Center as its terminal.

William M. Black is a steam-propelled, sidewheel dustpan dredge, named for William Murray Black, now serving as a museum ship in the harbor of Dubuque, Iowa. Built in 1934, she is one of a small number of surviving steam-powered dredges, and one of four surviving United States Army Corps of Engineers dredges. She was declared a National Historic Landmark in 1992. She is open for tours as part of the National Mississippi River Museum & Aquarium.

The Hotel Julien Dubuque is a hotel located in downtown Dubuque, Iowa at Second and Main streets. The hotel currently has 133 guest rooms, Caroline's restaurant, the Riverboat Lounge, the Potosa Spa, a pool and fitness center, and large banquet facilities. The interior redesign converted the existing 168 guest rooms into 133 luxury rooms and suites and restored the historic lobby and grand ballroom, while at the same time adding modern systems and amenities like a geothermal heating and cooling system, a reflective roof, a swimming pool and fitness facility. It was included as a contributing property in the Old Main Street Historic District in 1983 as the Julien Motor Inn.

Old Main Street Historic District is a nationally recognized historic district located in Dubuque, Iowa, United States. It was listed on the National Register of Historic Places in 1983. At the time of its nomination it consisted of 33 resources, which included 30 contributing buildings and three non-contributing buildings. In 2015 the boundaries were increased to include five more buildings. Four of the buildings are contributing properties that were excluded from the original district because they were slated to be torn down as a part of the expansion of U.S. Route 61. While the highway was built the buildings were spared. The fifth building is non-contributing as are three structures. This is primarily a commercial area located immediately south of the central business district. Originally, this is where the city's commercial district was located because of its proximity to the ferry and riverboat landings. After 1860 most of the larger retail businesses, banks, and professional offices moved further north on Main Street, and new wholesale businesses moved here and built new structures. The buildings are all constructed in brick and are between three and four stories tall. It is considered to be the "largest concentration of significant nineteenth-century commercial architecture" in Dubuque. The Bishop's Block (1887) and the German Bank (1901) are individually listed on the National Register, and the Hotel Julien Dubuque (1914) is also a contributing building.

The National Mississippi River Museum & Aquarium is a museum located in Dubuque, Iowa, USA. The museum is a property of the Dubuque County Historical Society, which also operates the Mathias Ham Historic Site. The museum has two buildings on its riverfront campus: the Mississippi River Center and the National River Center. The museum originally opened as the Fred W. Woodward Riverboat Museum on July 18, 1982 before being expanded and re-organized into its current form. The museum is an affiliate of the Smithsonian Institution, and is accredited by the American Alliance of Museums (AAM) and the Association of Zoos and Aquariums (AZA).

The Port of Dubuque Marina is primarily a transient marina, with limited seasonal slip rentals available. The Port of Dubuque Marina's seventy-eight (78) slips include fifty-four (54) 30", twenty (2) 40", and four (4) 50". By utilizing the end ties, or T-heads of the docks, the Port of Dubuque Marina can accommodate a boat up to 100" in length. The docks are rented out to boaters by the day, with a maximum stay of ten consecutive days. The Port of Dubuque Marina also offers an hourly rate for boaters who would like to dock and stay for only a short time and enjoy some of the many nearby attractions. In addition to slip rentals the Port of Dubuque Marina offers fuel sales (unleaded and diesel), and pump out services to visiting boats. The amenities building houses private boater restrooms with shower and laundry facilities, public restrooms, and a Marina convenience store.

The Dubuque Freight House is a historic building located in Dubuque, Iowa, United States. Built by the Chicago, Burlington and Northern Railroad (CB&N) in 1901, this was the third and last freight house built by a railroad in the Ice Harbor area. The other two facilities were built by the Illinois Central Railroad (1872) and the Chicago, Milwaukee and St. Paul Railroad (1874). These other two railroads were older, larger, and monopolized the bridge and tunnel that crossed the Mississippi River. The CB&N was fortunate that their freight house was located along the water's edge in that the river boats could tie up next to the building and load and unload cargo, and the railroad put box cars on ferries that docked in the Ice Harbor. The Dubuque Boat and Boiler Works were headquartered on the west end of the facility for 20 years beginning in 1952. Founded in 1852 as the Iowa Iron Works, they provided engines, boilers and other equipment for river boats, and water craft for the United States Navy, United States Coast Guard, and the United States Army Corps of Engineers. The building was listed on the National Register of Historic Places in 1979. It is now a part of the National Mississippi River Museum & Aquarium.

German Bank is a historic building located in the Lower Main Street district of Dubuque, Iowa, United States. The city's German community was its most prominent ethnic group in the mid to late 19th century. Like many other Iowa cities of that era, Dubuque had banks that were owned by, and catered to, members of their particular immigrant communities. T.H. Thedinga, the city's first German-born mayor, started this bank in 1864 to serve immigrant Germans. In 1868 it moved from its original location on Main Street and into the former Dubuque Miners' Bank building. That building was torn down in 1901 in order to construct this one. It was designed by Dubuque architect John Spencer in partnership with Chicago architect W.G. Williamson. The three-story brick building has a highly decorative main facade composed of polished pink granite on the main floor and terra cotta on the upper two floors. Decorative elements include egg-and-dart, Greek fret, a row of small lions' heads, bay windows, scroll pediments, imperial German eagles, and a bracketed cornice with dentils. The second and third floors are dominated by four fluted, banded columns with Corinthian capitals. The bank remained in operation here until 1932 when it closed in the Great Depression. Since 1946 the first floor has housed a restaurant and bar. The building was individually listed on the National Register of Historic Places in 1978. and it was included as a contributing property in the Old Main Street Historic District in 1983.

Diamond Jo Boat Store and Office, also known as the Dubuque Tank Terminal Co. and Inland Molasses Co. Operations Office, is a historic building located in Dubuque, Iowa, United States. This is the last remaining structure in the city that is associated with the steamboat era on the Mississippi River. Several other buildings associated with this line were destroyed in a 1909 fire. This building housed the headquarters of the Diamond Jo Line from the mid-1880s until it was sold to the Streckfus Line in 1911. Originally headquartered in McGregor, Iowa, Joseph Reynolds started in the steamboat business after the American Civil War shipping wheat Minnesota and the Chicago and Northwestern railhead at Fulton, Illinois. In the last quarter of the 19th century the Diamond Jo Packet Line was one of the most active steamboat lines on the upper Mississippi. As railroads gradually took the freight business away from steamboats, Reynolds started to build passenger boats and he bought boats from other lines. The offices were located on the east end of the simple, two-story, brick building, and the rest was used for storage. The building was listed on the National Register of Historic Places in 1974. The structure resides at the corner of Jones and Water St. in Dubuque Iowa.

St. Raphael's Cathedral is a Catholic cathedral and a parish church in the Archdiocese of Dubuque located in Dubuque, Iowa. The parish is the oldest congregation of any Christian denomination in the state of Iowa. The cathedral church, rectory, former convent, and former parochial school building are contributing properties in the Cathedral Historic District on the National Register of Historic Places.

Five Flags Center is a multi-purpose facility in downtown Dubuque, Iowa. It is named for the five flags that have flown over Dubuque; the Fleur de Lis of France (1673–1763), the Royal Flag of Spain (1763–1803), the Union Jack of Great Britain (1780, during a brief interruption of Spanish rule), the French Republic Flag of Napoleon (1803) & America's Stars and Stripes (1803–Present).