Fred Schnauber House

The Chicago, Milwaukee and St. Paul Depot in Yankton, South Dakota was built in 1905 by the Chicago, Milwaukee, St. Paul and Pacific Railroad (otherwise known as The Milwaukee Road). Prior to the 1870s, Yankton was served by steamboats along the Missouri River. As service declined, railroads took over to serve the communities in South Dakota. In the late 1870s, the Dakota Southern Railroad entered Yankton. Shortly afterward, the Dakota Southern was bought by The Milwaukee Road. The Milwaukee Road then expanded westward toward Rapid City, South Dakota and the Black Hills. In 1905, The Milwaukee Road built its depot in Yankton. Using a common design, the depot is rectangular in shape and single story. It is built of brick with wood and stone trim. There is a covered area at one end of the depot that leads to the waiting room. A baggage room is located at the other end and the station agent's office is located between the two. As railroad passenger service declined after the 1940s, the depot was sold. The Milwaukee Road itself went bankrupt in the 1980s, and the tracks adjacent to the depot were sold to BNSF Railway predecessor Burlington Northern. At the time of nomination to the National Register of Historic Places, the depot was used as offices for a local cable television company. In 2008, the depot houses the offices of an architectural firm. The depot was listed in the National Register because of its architecture and also because of it association with the commercial development of Yankton and the development of railroads in South Dakota.

The Federal Prison Camp, Yankton (FPC Yankton) is a minimum-security United States federal prison for male inmates in Yankton, South Dakota. It is operated by the Federal Bureau of Prisons, a division of the United States Department of Justice. The prison is situated on the former campus of Yankton College, which operated until 1984. The site was converted to a prison in 1988. FPC Yankton is located 60 miles (97 km) northwest of Sioux City, Iowa, and 85 miles (137 km) southwest of Sioux Falls, South Dakota.

Yankton College was a private liberal arts college in Yankton, South Dakota, United States, affiliated with the Congregational Christian Churches (later the United Church of Christ). Yankton College produced nine Rhodes Scholars, more than any other South Dakota higher education institution.

The Burns House is a historic house in Yankton, South Dakota. It was built in 1886 for Robert Burns, a banker who served as the president of the Mortgage Bank. It was acquired by George Durand, the vice president of Yankton College, in the 1900s. Durand and his wife were art collectors. The house was designed in the Queen Anne architectural style, with a tower. It has been listed on the National Register of Historic Places since February 9, 2001.

The Yankton Carnegie Library is a historic building in Yankton, South Dakota. It was built as a Carnegie library in 1902–03, and is Neoclassical style in style. It was built by German-born contractor August Goetz. It was a public library from 1903 to 1973.It served as the town's library from 1903 to 1973, and later served as the Lewis and Clark Mental Health Center.It has been listed on the National Register of Historic Places since August 7, 1979.

The William J. Fantle House is a historic house in Yankton, South Dakota. It was built in 1917 for William J. Fantle, the co-founder of Fantle Bros, a dry good store. It was designed in the Prairie School style by architect Peter J. Linhoff. It has been listed on the National Register of Historic Places since October 10, 1989.

The Dr. B.M. Banton House is a historic two-story house in Yankton, South Dakota. It was built in 1920-1921 and designed in the California bungalow style by Dr. B.M. Banton, a dentist. It has been listed on the National Register of Historic Places since October 8, 1987.

The Charles Gurney Hotel is a historic three-story building in Yankton, South Dakota. Replacing the original St. Charles Hotel (constructed in 1870 by J.W.C. Morrison of local cottonwood lumber), the present building was built in 1891 with brick and Sioux Falls granite. It was designed in the Richardsonian Romanesque Revival style by architect J.H. Coxhead. It was originally known as the Hotel Pierce, and it was built where the 1870 St. Charles Hotel once stood. It was later renamed the Portland Hotel by its new owner, Alfred Crebbin, presumably in recognition of the importance of the local manufacture of Portland cement (see Western Portland Cement plant). In the 1940s, it was acquired and remodelled by Charles Gurney, and it became known as the Charles Gurney Hotel. It was purchased by Elza Anderson in 1962. It has been listed on the National Register of Historic Places since August 3, 1979.

The Bruce-Donaldson House is a historic two-story house in Yankton, South Dakota. It was built in 1879 for James E. Bruce, who sold it to Fred Donaldson, an immigrant from Sweden who became a grocer in Yankton. It was designed in the Italianate architectural style. It has been listed on the National Register of Historic Places since March 5, 1982.

The Governor John L. Pennington House, at 410 E. Third St. in Yankton, South Dakota, was built in 1875. Also known as South Dakota Magazine Office in 1987, it is a simplified Italianate-style building. It was registered with the National Register of Historic Places in 1988.It was home during 1875 to 1891 of Dakota Territory governor John L. Pennington who served as governor for a four-year term from 1874 to 1878.

The Ohlman-Shannon House is a historic house in Yankton, South Dakota. It was built in 1871 for Charles Mclntyre, who sold it to Martin P. Ohlman, Sr. in 1878. Ohlman was a real estate investor who served as the president of the American National Bank and as a director and treasurer of the Yankton Bridge and Ferry Company. The house remained in the Ohlman family until 1975, when his granddaughter, married to William Shannon, sold it to John Harmelink. It was designed in the Italianate architectural style. It has been listed on the National Register of Historic Places since May 28, 1976.

The Harold A. (H.A.) Doyle House is a historic house in Yankton, South Dakota. It was built in 1924 for Harold A. Doyle, a trial lawyer, and designed in the American Craftsman style by architect William L. Steele. It has been listed on the National Register of Historic Places since October 25, 1990.