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The Neptune Theatre, formerly known as U-Neptune Theatre, is a performing arts venue in the University District neighborhood of Seattle, Washington, United States. Opened in 1921, the 800-seat venue hosts a variety of events, including dance and music performances, film screenings, and arts education. It was primarily used for screening classic films prior to a 2011 renovation. In 2014, the theater and building were designated a Seattle landmark. The Neptune Theatre is operated by the non-profit Seattle Theatre Group, which also operates the Paramount Theatre and Moore Theatre. It is one of several venues that host the annual Seattle International Film Festival.

Leon Coffee House is a coffee shop in Seattle's University District, in the U.S. state of Washington. Established in 2021, the family-owned business is among the city's only Mexican coffee shops and has a colorful interior with various backdrops and decorations. The menu includes coffee and espresso drinks, horchata and other varieties of lattes, as well as churros, flan, nachos, pastries, tamales, and waffles, among other food items.

The UW Tower is a high-rise office building complex located in the University District of Seattle, Washington, United States. It was completed in 1975 and serves as the head offices of the University of Washington. The 22-story tower was designed by NBBJ. It reaches a height of 99 m (325 ft), making it Seattle's tallest building outside the Downtown area. The tower was originally constructed as Safeco Plaza to serve as Safeco Insurance's headquarters. It was generally referred to as the Safeco Building. Safeco sold the property to the University of Washington in 2006 for $130 million, and moved out one year later. The purchase from Safeco included Safeco Tower, three adjacent buildings, a residential building with 29 units, two parking garages and two surface parking lots. Presently the university properties consist of the UW Tower itself, Buildings A, C, O, and S, the Collegiana building, two garages, and two surface lots.

U District station is a light rail station on Line 1 of Sound Transit's Link light rail system in Seattle, Washington, United States. It is located in the University District neighborhood, near the University of Washington campus. The underground station has two entrances along Brooklyn Avenue Northeast at 43rd and 45th streets. Construction of the station began in 2012 as part of the Northgate Link extension, which was approved by voters in a 2008 ballot measure. It opened on October 2, 2021, along with the rest of the extension. Light rail trains arrive at the station at frequencies of up to eight minutes during peak periods and 10–15 minutes at other times. U District station also includes five bus bays served by several King County Metro and Sound Transit Express routes that connect to nearby areas.

University Way Northeast, colloquially The Ave (no period; pronounced /æv/), is a major street and commercial district in the University District of Seattle, Washington, located near the University of Washington (UW) campus. Once "a department store eight blocks long," The Ave has gradually turned into what now resembles an eight-block-long global food court. The story of The Ave reflects the dynamics of many urban neighborhoods and the social and economic problems of countless American cities, though it is also a crossroads of diverse subcultures. It is patronized by many of the nearly 96,900 students, faculty, and staff of the UW and by a population of homeless or transient individuals, most of whom are youth. University Way NE is a collector (tertiary) arterial, running 1.2 miles (1.9 km) from just below NE Pacific Street in the south to NE Ravenna Boulevard and Cowen Park in the north, where it turns into Cowen Place NE. The street had been known as "The Ave" since the early 20th century and while it was no longer officially an avenue, the nickname stuck.

Sweet Alchemy Ice Creamery, or simply Sweet Alchemy, is an ice creamery based in Seattle, Washington. The business has shops in the University District and Ballard neighborhoods and on Capitol Hill. Owner Lois Ko opened the first location near the University of Washington in 2016. The Ballard location opened in 2019 and shares a space with Mighty-O Donuts, and the Capitol Hill shop opened in Chophouse Row in 2020. Sweet Alchemy offers a variety of ice cream and other desserts, and makes cakes, cones, cookies, and toppings in-house. The business pasteurizes its dairy from local farms daily. It has garnered a positive reception and is considered among Seattle's best ice cream shops.

The University Presbyterian Church in Seattle, Washington, United States is a Presbyterian Church (U.S.A.) congregation with 3,418 members. The current senior pastor is George Hinman.The church was founded in 1908. The church had a large membership increase during the 1980s, when it was led by pastor Bruce Larson; Larson subsequently became co-pastor of the Crystal Cathedral in Garden Grove, California. In 2001, the average weekly attendance was 5,000; it is now 3,875.Earl Palmer was senior pastor for 15 years, following Bruce Larson and preceding George Hinman. Palmer retired to form Earl Palmer Ministries where he continues teaching ministering, and mentoring. Palmer's articles, videos, and sermons can be heard and downloaded from his web site, including episodes from the Kindlings Muse, Earl's lectures on C. S. Lewis, and hundreds of sermons reaching back to the ’70s. The current organ was completed in 1999. The Reuter Organ, Opus 2196, was built in Lawrence Kansas. The organ committee, their consultant, Joseph Adam, and organist JoAnn Stremler helped collaborate on the new organ’s design with Reuter’s regional representative, David R. Salmen. Senior Pastor Dr. Earl F. Palmer said of the organ: "In this house of worship we call University Presbyterian Church, that gift of great and tender sound is ours. Tears still well up in my eyes when I hear its subtlety and grandeur." University Presbyterian Church provides ministries for "the mentally ill, homeless, teens living on the streets, and those who are in prison." The congregation was a pioneer in the practice of sending short-term mission teams overseas.

Off the Rez is a restaurant in Seattle, in the U.S. state of Washington. Owned by Mark McConnell of the Blackfeet Nation in Browning, Montana, as well as his partner, Cecilia Rikard, the business has operated as a food truck and as a cafe at the Burke Museum of Natural History and Culture.

Bulldog News is a coffee shop and newsstand in Seattle, in the U.S. state of Washington. The cafe has operated in the University District since 1983, and has had an outpost on Capitol Hill.

The Grand Illusion Cinema is the longest running independent cinema in the city of Seattle, Washington, and has become a landmark of the film community. Opened as The Movie House in March 1970 by Randy Finley at 1403 NE 50th St in a converted dentist's office the cinema became the city's first intimate arthouse and showcased foreign and revival films. The cinema's success led to Randy creating the Movie House in Portland, Oregon in 1973. He then took over the Guild 45th Theater and created the Seven Gables Theatre at 50th and Roosevelt in Seattle. They, and other theaters, became the Seven Gables Theatre Chain, which was later merged with Landmark Theatres. The Grand Illusion was never part of the Seven Gables chain and remained a popular independent venue. Non-profit film arts organization, the Northwest Film Forum, saved the theater from closure in 1997, remodeled it, and revitalized interest in the institution. In 2004 the cinema was sold to a group of investors including several staff members. It exists today as a completely volunteer-run, non-profit organization. The Grand Illusion shows a wide variety of films ranging from new independent and foreign films, repertory classics, documentaries, and a consistent supply of "late nights" on the weekend which feature horror, sci-fi, and exploitation films. Over the years the cinema has been host to such people as Quentin Tarantino, Takashi Miike, Alex Cox, Eddie Izzard, Stuart Gordon, Don Hertzfeldt, Dennis Nyback, and the cast of Troll 2. In 2008, along with such seminal theatres as the Alamo Drafthouse in Austin and the Film Forum in New York, The Grand Illusion was named one of the best movie houses in America by Paste Magazine.

Café Allegro is a coffeeshop in the University District of Seattle, Washington, United States. It is notable for being one of the city's first espresso shops and for its role in the history of Starbucks, as the place where founding proprietor Dave Olsen designed the Starbucks coffee product line. Situated in an alleyway, the cafe features multiple entrances and rooms.

In September 2018, the Center for Sensorimotor Neural Engineering (CSNE) changed its name to the Center for Neurotechnology (CNT) to highlight the role of neurotechnologies in healing the brain and spinal cord. The CNT is an Engineering Research Center funded by the National Science Foundation to create devices to restore the body's capabilities for sensation and movement. The National Science Foundation has awarded the CNT $~30 million since 2011.The CNT is based at the University of Washington, and its main partner organizations are Massachusetts Institute of Technology (MIT) and San Diego State University (SDSU). CNT researchers specialize in fields related to neural engineering including: Biological and traditional engineering, computer science, applied mathematics, neurological surgery, neuroscience and neurobiology and philosophy. Center faculty also hail from various fields of medicine and assist with real-world implementation of designs. The CNT places a strong emphasis on neuroethics, exploring how ethical issues such as identity, privacy, and moral or legal responsibility in relation to the expanding field of neural technologies.