Church of the Good Shepherd (Thomasville, Georgia)

The Stevens Street Historic District is a 175 acres (71 ha) historic district in Thomasville, Georgia. It is located one block northwest of Thomas County Courthouse. It was listed on the National Register of Historic Places in 2001. It was noted to be "an intact African-American neighborhood that developed in Thomasville, Thomas County following the end of the Civil War." It then included 341 contributing buildings and three contributing structures, as well as 83 non-contributing structures.Especially significant buildings include the Clay Street YMCA and the Recreation Center at 404 West Calhoun Street.

The Dr. David Brandon House, also known as Hayes House, in Thomasville, Georgia, was built as a one-story brick house in 1851. A second floor with mansard roof was added in the 1870s. It was listed on the National Register of Historic Places in 1970.The house was built for Thomas Jones of Greenwood Plantation to serve as a wedding gift for his daughter Harriet and her husband, Dr. David S.Brandon. The house was sold to Mrs. John H. Hayes in 1862 and remained in the Hayes family in 1970.

The Ephraim Ponder House in Thomasville, Georgia, also known as the Sholar House, was built c.1854-56 It was listed on the National Register of Historic Places in 1970.It was built by Epraim Ponder, and served part of old Young's Female College in Thomasville in 1869 and latterly as home of the president of the old College. At the time of NRHP listing it was owned by John Sholar and wife.Its south facade is Greek Revival in style and faces the former Female College property.

Thomasville Commercial Historic District is a historic district that was listed on the National Register of Historic Places in 1984 and was both increased and decreased in 2004. The modified district, about 60 acres (24 ha) in size, then included 123 contributing buildings, three contributing structures, and a contributing object, as well as 65 non-contributing buildings.The district consists primarily of one- and two-story commercial buildings built between 1880 and the 1940s.It has a number of buildings dating back to the 1880s. For the historic district the Thomasville Main Street Program helped raise over $44 million for the district.The district includes: Thomas County Courthouse, 225 North Broad Street, separately NRHP-listed Thomasville Depot, separately NRHP-listed (three contributing buildings; within the 2004 increase) B'nai Israel Synagogue, separately NRHP-listed (within the 2004 increase) Hollybrook Building - Brokerage Exchange built in 1882 Lapham-Patterson House Thomasville Cultural Center

The Thomas County Courthouse is an historic government building built in 1858 and located on North Broad Street in Thomasville, Georgia, the seat of Thomas County. It was designed by architect John Wind.It was added to the National Register of Historic Places on June 22, 1970. It is also a contributing building in the NRHP-listed Thomasville Commercial Historic District.

The Hardy Bryan House, also known as Cater House, in Thomasville, Georgia, was built in c.1833. It is a well-preserved example of an antebellum plantation house. It was listed on the National Register of Historic Places in 1970. It is also a contributing building in the National Register-listed Dawson Street Residential Historic District. It is a two-and-a-half-story Plantation Style house with a two-story portico supported by four square columns. As of 1970, all of its windows were 16 over 16, many with their original glass.

The Big Oak is a large live oak (Quercus virginiana) located in Thomasville, Georgia, in the United States at the corner of Crawford Street and Monroe Street. The Big Oak is one of many historic landmarks located in Thomasville. The Big Oak was one of the earliest trees registered with the Live Oak Society. Registered by P.C. Andrews in 1936, the Big Oak was the forty-ninth live oak registered. At the time of registration, the Big Oak's girth was 21 feet 6 inches.

The Thomasville Depot in Thomasville, Georgia was built in 1914. It was listed on the National Register of Historic Places in 1988. The station served the Atlantic Coast Line Railroad. In later years it served the ACL's successor, the Seaboard Coast Line, and also Amtrak. Trains included the South Wind (Illinois Central Chicago–Miami train, running over ACL, later, SCL lines) and Amtrak's Floridian (also Chicago–Miami). The station also served a side branch of the ACL's (later, SCL) Champion originating in Montgomery, Alabama and heading northeast to New York City. Passenger service ended with the demise of the Floridian in 1979. The depot building has two stories and some Mission/Spanish Revival styling. The listing included the depot building, a train platform shed, and a Railway Express Agency (REA) building.The three buildings are also contributing buildings in the Thomasville Commercial Historic District.

The Dawson Street Residential Historic District, in Thomasville, Georgia, is a 200-acre (0.81 km2) historic district which was listed on the National Register of Historic Places in 1984. It then included 380 contributing buildings and three contributing sites. It is located to the north of the city's commercial center and its courthouse square. As well as houses, the district includes several churches, two historic cemeteries (one for whites and one for blacks), a historic city park, and pecan orchards associated with some of the houses.It includes two properties already separately-listed on the National Register: Hardy Bryan House (or Carter House), 312 North Broad Street, a Greek Revival house built by a carpenter/builder which is believed to be one of the earliest surviving houses in Thomasville; Lapham-Patterson House (1885), 626 North Dawson Street, a National Historic Landmark.Also notable in the district are: several rare examples of single pen houses on Broad Street and Lutten Lane Hardeway House (1856), 526 North Dawson Street) designed by builder/architect John Wind 312 North Dawson Street (1905), a "concrete stone" structure built as the administration building for Young's Female Academy.

The Lapham–Patterson House is a historic site at 626 North Dawson Street in Thomasville, Georgia. The house, built between 1884-85 as a winter cottage for businessman C.W. Lapham of Chicago, is a significant example of Victorian architecture. It has a number of architectural details, such as fishscale shingles, an intricately designed porch, long-leaf pine inlaid floors, and a double-flue chimney. Inside, the house was well-appointed with a gas lighting system, hot and cold running water, indoor plumbing, and modern closets. Its most significant feature is its completely intentional lack of symmetry. None of the windows, doors, or closets are square. The house is a Georgia Historic Site and is also a National Historic Landmark, designated in 1973 for its architecture. It is also a contributing building in the National Register-listed Dawson Street Residential Historic District. The three-story structure has a mellow-yellow exterior with brick-red roof and chimneys. At the core of the house is a hexagonal-shaped room. There are at least 50 exits; Mr. Lapham had been in the Great Chicago Fire and subsequently became paranoid about being trapped in a burning building. The house was deliberately constructed slightly askew to take advantage of sunlight entering the third floor during the Spring and Fall Equinoxes. Within is a gentlemen's parlor with a small stage featuring a stained-glass window in the center. In the fretwork outside the room over the balcony are animal and amorphous shapes cut into the wood. In the center is a cutout of what is presumably the head of Mrs. O'Leary's cow. During the Spring and Fall Equinoxes the patterns are projected by sunlight onto the floor through the glass. The total effect is that, in the center of the stained glass window's colorful pattern on the floor, the shadow of the cow's head can be seen. Mr. Lapham was a Quaker.

The Dewey City Historic District is a 110 acres (45 ha) historic district in Thomasville, Georgia which was listed on the National Register of Historic Places in 2008. It is an intact historically African-American neighborhood.It then included 110 contributing buildings, a structure, and a contributing site. It also included 100 non-contributing buildings and 35 non-contributing sites, and a non-contributing object.

The Wright House is a historic house located at 415 Fletcher St. in Thomasville, Georgia.