16th & California and 16th & Stout stations

Downtown Denver is the main financial, commercial, business, and entertainment district in Denver, Colorado. There is over 23 million square feet (2,100,000 m2) of office space in downtown Denver, with 132,000 workers. The downtown area consists mostly of the neighborhoods of Union Station and Central Business District. LoDo and RiNo are notable districts within downtown. Some of the more popular specific attractions include the 16th Street pedestrian mall, Larimer Square, the re-emerging Theatre District near Curtis and 14th, and Civic Center Park. Surrounding neighborhoods include Capitol Hill and Uptown to the east, Highland to the west, Five Points to the north, and the Golden Triangle to the south.

The Denver Dry Goods Company Building is a historic department store building located in downtown Denver, Colorado. For a while, the store was claimed to be the largest department store west of Chicago. A description on one postcard from 1916 read: "The Largest Store in the Central West, 400 Feet long-Seven Acres Floor Area, 1,200 Employees, A $1,500,000 Stock, 15th to 16th on California Street Denver Colorado". The flagship store of The Denver Dry Goods Company, the retailer was part of Associated Dry Goods, and under ADG the downtown Denver store was renovated. Many Colorado residents fondly recall the stores' motto, "Where Colorado Shops With Confidence." The store was acquired by May Company as part of Associated Dry Goods Corp. in 1986. Originally built in 1889, the store was expanded in 1898, 1906 and 1924. It was converted to apartments in 1994.

United Western Financial Center is a 357 ft (109m) tall high-rise office building located at 700 17th Street in the city Denver, Colorado. It was completed in 1961 and has 24 floors. It is the 28th tallest building in Denver. It was designed by the architecture firm Raymond Harry Ervin & Associates in the modernist style.

The Boston Building, built in 1890, is a historic building in Denver, Colorado. It was designed by the firm Andrews, Jaques & Rantoul – the same architects who designed the nearby Equitable Building – and was dubbed the first "strictly modern office building" in Denver at time of its construction. Standing 9 stories tall (35 meters high), the building is located at 828 17th Street in Denver's historic district, on the corner of E. 17th St. and Champa. In 1978 the Boston Building received National Historic Landmark status under the Historic Resources of Downtown Denver Multiple Property Submission (Building Number: 5DV.108). The building has also been deemed a Denver historic landmark. In 1998, the building was renovated and joined with the Kistler Building to create one and two-bedroom apartment lofts. It is now also known as Bank Lofts.

The Bank Lofts is a building in Denver, Colorado. Constructed in 1921, the building is listed on the National Register of Historic Places.

Dominion Towers is an office complex in Denver, Colorado. It consists of two adjoining towers, and was built in 1982. The taller one, Dominion Towers South, is 384 feet (117 m) tall and has 28 floors. The buildings have pink granite facades and blue-tinted windows.

The First National Bank Building, also known as the American National Bank of Denver, Colorado was originally built as the headquarters building in 1911. Located at the corner of 17th and Stout Streets, it is now the Magnolia Hotel. It was listed on the National Register of Historic Places in 1996. In 2000, it became part of the Downtown Denver Historic District.

The Equitable Building is a historic commercial office building located in Denver, Colorado.

Johns Manville Plaza is a 404-foot-tall skyscraper (123 m) in Denver, Colorado. It was completed in 1978 and has 29 floors. The building was designed by Hellmuth, Obata and Kassabaum and built by Al Cohen Construction. It is owned by Crescent Real Estate Equities Company, and is the 16th tallest building in Denver. Reflective solar glass windows alternating with 5-foot-wide columns (1.5 m) makes up the outer walls. A plaza, basement, and loading dock are shared with 707 17th Street.

The Hyatt Regency Denver at the Colorado Convention Center is a 489 ft (149 m) tall skyscraper in Denver, Colorado. It was constructed from 2003 to 2005 and has 38 floors. It is the 8th tallest building in Denver. It is currently owned by Plant Holdings NA, Inc. and leased to Hyatt Corporation.

The Filbeck Building is a historic 1917 building in Denver, Colorado, designed by architect John J. Huddart. Located at 1527 Champa Street, it is next to the Roger & Son Mortuary/Yankee Dollar Building. It has been home to the Champa Bar, the Changing Scene Theater, and the Bovine Metropolis Theater.

The Joslin Dry Goods Company Building (also known as the Tramp Building or the Joslin Building) is a historic building in downtown Denver, Colorado.