Pliny and Adelia Fay House

The West Hill Historic District in Muscatine, Iowa is a historic district that was listed on the National Register of Historic Places in 2008. At that time, it included 258 contributing buildings, two contributing objects, two contributing sites, and 67 non-contributing buildings. The city of Muscatine was established as Bloomington in 1836. The original town was built on land that is generally flat along the Mississippi River. Residential areas were built on the surrounding hills, while commercial and industrial interests developed on the flatter land near the river. The West Hill Historic District is immediately to the west of the Downtown Commercial Historic District. The period of significance for West Hill begins in 1839 and ends in 1958. Some of the largest and oldest historic houses in Muscatine are located here, but it also includes smaller residences of the working and middle class. By 1915, 180 of the historic houses had been built. The rest were built from 1916 to 1958. Another eight houses were built between 1960 and 1995. A majority of the houses (80%) are two stories in height. Frame construction (70%) outnumbers brick construction (30%). The architectural styles that were prominent across the country are also found here and were built at the time they were popular.

J. C. B. Warde House is an historic residence located in Muscatine, Iowa, United States. It has been listed on the National Register of Historic Places since 1979. The house was included as a contributing property in the West Hill Historic District in 2008.

The Clark–Blackwell House is an historic residence located in Muscatine, Iowa, United States. It has been listed on the National Register of Historic Places since 1983. The house was included as a contributing property in the West Hill Historic District in 2008.

The Alexander Clark House is a historic house located in Muscatine, Iowa, United States. The house is associated with Alexander Clark (1826–1891), an African American civil rights pioneer and US Minister to Liberia. Clark was a 19th-century abolitionist who made his home in Muscatine for most of his adult life. He fought and won for the integration of public schools in Iowa when his daughter was forbidden to attend her neighborhood school. The case went to the Iowa Supreme Court, which resulted in the integration of all schools in the state. He was an associate of Frederick Douglass, helped to establish Iowa's only Colored regiment during the American Civil War, and the African Methodist Episcopal Church in Muscatine. Clark was named the Minister to Liberia in 1890 by President Benjamin Harrison, where he died a year later. The house was built in 1879 after a fire destroyed Clark's previous house. It was moved 200 feet (61 m) from its original location in 1975, The house was individually listed on the National Register of Historic Places in 1976. It was included as a contributing property in the West Hill Historic District in 2008.

The McKee Button Company is a historic building in Muscatine, Iowa, United States. The city was known as the Pearl Button Capital of the World because of the numerous firms that produced the buttons here through the 1960s. The Peerless Button Company was established by James McKee and his brother-in-law William Bliven in 1895. Two years later the company's name was changed to the McKee and Bliven Button Company. They built this building in 1907. The company has been known as the McKee Button Company since 1925. The building was listed on the National Register of Historic Places in 2020 and was purchased by Kent Corporation of Muscatine, Iowa.In March of 2022, Kent Corporation announced that they would begin transforming the McKee building into offices while focusing on preserving the building's history. They estimated the project would be complete in the spring of 2024.

Welch Apartments is an historic building located in downtown Muscatine, Iowa, United States. The Scott House hotel existed on this property prior to this building, which was constructed about 1900. The Italianate-style building contain 26 units with different floor plans. The main floor contains commercial space. The four-story structure measures 120 by 80 feet (37 by 24 m). The dominant feature of the exterior is the bay windows that protrude from the wall surface. The pressed-metal cornice unifies the building's composition. High parapet gables are located above the cornice. They are executed in the Flemish Renaissance style. The building has been listed on the National Register of Historic Places since 1979. It became a contributing property in the Downtown Commercial Historic District in 2006.

First Presbyterian Church is a Presbyterian Church (USA) church located in Muscatine, Iowa, United States. It, along with the attached Sunday School building, were listed on the National Register of Historic Places in 1977.

The Downtown Commercial Historic District in Muscatine, Iowa is a historic district that was listed on the National Register of Historic Places in 2006. At that time, it included 93 contributing buildings, one other contributing object, and 18 non-contributing buildings. The city of Muscatine was established as Bloomington in 1836. The original town was built on land that is generally flat along the Mississippi River. Residential areas were located on the surrounding hills. Commercial and industrial interests developed on the flatter land near the river. Muscatine's commercial and industrial center had developed in a 12-block area along Front Street, now Mississippi Drive, and 2nd Street between Pine Street and Mulberry Street by 1874. This area, represented by the Downtown Commercial Historic District, is the city's original commercial area. Within its boundaries is a large number of 19th-century commercial buildings, many of which were modified in the first half of the 20th century.

Muscatine ( muss-kə-TEEN) is a city in Muscatine County, Iowa, United States. The population was 23,797 at the time of the 2020 census, an increase from 22,697 in 2000. The county seat of Muscatine County, it is located along the Mississippi River. The local business association states that the name Muscatine is not used by any other community.Muscatine is the principal city of the Muscatine Micropolitan Statistical Area (2010 census population 54,132) as of 2011 the estimate was 54,184, which includes all of Muscatine and Louisa counties, making it the 283rd-largest micropolitan statistical area.

S. M. McKibben House is an historic residence, now office building, located in Muscatine, Iowa, United States. It has been listed on the National Register of Historic Places since 1974.

Trinity Episcopal Church is a parish church in the Diocese of Iowa. The church is located in Muscatine, Iowa, United States. It was individually listed on the National Register of Historic Places in 1974. In 2006 it was included as a contributing property in the Downtown Commercial Historic District.

The Muscatine County Courthouse in Muscatine, Iowa, United States, was built in 1909. It was listed on the National Register of Historic Places in 1981 as a part of the County Courthouses in Iowa Thematic Resource. The courthouse is the third building the county has used for court functions and county administration.