Wyoming is a frame historic house located in Clinton in Prince George's County, Maryland, United States. It consists of three separate and distinct sections: the main block built in the third quarter of the 18th century, a ca. 1800 kitchen, and a connecting two-bay section of c. 1850. The house is a well-preserved example of Maryland's gambrel-roofed colonial architecture, and is more specifically noteworthy as an excellent example of southern Maryland tidewater architecture. With the exception of Mt. Pleasant, the house may have the oldest boxwood in the county planted on its grounds.Wyoming is also significant historically as the ancestral home of the Marburys, a family which produced many of Maryland's political, professional, and judicial leaders through the 18th, 19th, and 20th centuries. The house has been continuously owned by members of the family from its construction c. 1750 until 1973. A small Marbury family cemetery is located south of the main house in a grove of trees. This includes a large obelisk dedicated to Catharine Taylor Marbury, the wife of Fendall Marbury, who died in 1866. Wyoming is also notable for its great planting of boxwood, forming a walkway leading to the front of the house.Wyoming was part of an original land grant known as Appledore, patented by Robert Middleton in 1688. Appledore is seen as #9 on the map of Tracts of the Lower Piscataway Hundred before April 23, 1696. The name "Wyoming", according to the Marbury family history, was chosen by a daughter of the family (Cora Marbury) after a favorite poem, "Gertrude of Wyoming", written by Thomas Campbell in 1809. The poem deals with a famous Indian massacre in the Wyoming Valley of Pennsylvania, and was a favorite of Cora's.