Sproat Street/Adelaide Street station

Little Caesars Arena is a multi-purpose arena in Midtown Detroit. Opened on September 5, 2017, the arena, which cost $862.9 million to construct, replaced Joe Louis Arena and The Palace of Auburn Hills as the home of the Detroit Red Wings of the National Hockey League (NHL) and the Detroit Pistons of the National Basketball Association (NBA), respectively. The arena features a unique, clear plastic roofed concourse connecting it to offices and shops surrounding it. It was designed to be the flagship of a new $2.1 billion 650,000-square-foot (60,000 m2) sports and entertainment district, The District Detroit, with mixed-use neighborhoods with new residential and retail outlets located around the Cass Corridor, Ford Field, and Comerica Park. However, this has yet to materialize.

The Woodward Avenue Baptist Church was a Church located at 2464 Woodward Avenue in Detroit, Michigan. It was listed on the National Register of Historic Places in 1982, but was destroyed by fire in 1986 and delisted in 1988.

The Inn at 97 Winder is a luxurious historic Inn located at 97 Winder Street in Midtown Detroit, Michigan, within the Brush Park district. Originally known as the John Harvey House, it was listed on the National Register of Historic Places in 1991. The Detroit hotel is two blocks from Comerica Park and three blocks from Ford Field.

The Elisha Taylor House is a historic private house located at 59 Alfred Street in Midtown Detroit, Michigan, within the Brush Park district. The house was designated a Michigan State Historic Site in 1973 and listed on the National Register of Historic Places in 1975. Since 1981, it has served as a center for art and architectural study, known as the Art House.

The Hudson–Evans House (also known as the Joseph Lothian Hudson House or the Grace Whitney Evans House) is the private, single-family house located at 79 Alfred Street in Midtown Detroit, Michigan, within the Brush Park district.

St. John's Episcopal Church is an antebellum-era church located at 2326 Woodward Avenue (at the corner of Woodward and the Fisher Freeway service drive) in Downtown Detroit, Michigan. It is the oldest church still standing on Woodward Avenue, an area once called Piety Hill for its large number of religious buildings. The church was listed on the National Register of Historic Places in 1982 and designated a Michigan State Historic Site in 1987.

The Study Club fire killed 22 people and injured over 50 in a Detroit, Michigan dance hall on September 20, 1929.The club was located in the old theater district, at 65 East Vernor Highway, in Detroit. Until the fire, the Study Club operated as a speakeasy nightclub, where alcohol was being illegally sold during Prohibition. The fire is a historic case study of disasters in nightclubs, specifically dealing with hazards of flammable materials.

The First Unitarian Church of Detroit was located at 2870 Woodward Avenue in Midtown Detroit, Michigan. Built between 1889 and 1890, it was listed on the National Register of Historic Places in 1982. It was destroyed by fire on May 10, 2014.

The Bernard Ginsburg House is a single-family private residence located in Midtown Detroit, Michigan, within the Brush Park district. It was listed on the National Register of Historic Places in 1991.

The Ecumenical Theological Seminary is a private seminary in Detroit, Michigan. Founded in 1980 as the Ecumenical Theological Center, the seminary offers graduate degrees and certificates in religious studies. It is housed in a building built in 1889 to house the First Presbyterian Church; the seminary began leasing the building in 1992 and was donated the building, lands, and endowment in 2002.

The Park Avenue Hotel was a hotel in the Cass Corridor of Detroit, Michigan. It was listed on the National Register of Historic Places in 2006. It was also known as Salvation Army Harbor Light Center and is not to be confused with Park Avenue House, also once known as Park Avenue Hotel. The building was imploded on July 11, 2015.

Montcalm Street is a QLine streetcar station in Detroit, Michigan. The station opened for service on May 12, 2017, and is located at the northern end of Downtown Detroit. During the planning stage the station was known as Foxtown.