Blackstone River Valley National Heritage Corridor

The George Clapp House is a historic house at 44 North Street in Grafton, Massachusetts. Built about 1835, it is the town's only significant example of high-style Greek Revival architecture, with temple treatment on both the front and one side. The house was listed on the National Register of Historic Places on August 21, 1997.

Grafton Public Library is located in Grafton, Massachusetts. The building was built in 1927 with money donated by Jerome Wheelock, a local inventor. The 2009 population estimate is over 17,700. GPL belongs to Massachusetts Library System (MLS) and Central/Western Massachusetts Automated Resource Sharing, Inc. (C/W MARS).

The Grafton Inn is a historic inn at 25 Grafton Common in Grafton, Massachusetts. The three-story wood-and-brick building was built in 1805 by Samuel Wood, with a design influenced by the work of Charles Bulfinch. The building was significantly enlarged c. 1865–75, doubling its size and adding the Italianate front porch. It is a wood-frame structure, with brick ends, a hip roof, and cupola-like belvedere.The inn was listed on the National Register of Historic Places in 1980, and was included in the Grafton Common Historic District in 1988. It is still in operation as a restaurant, bar, and seven-room inn.

The Grafton Common Historic District encompasses the historic village center of Grafton, Massachusetts. The center consists of a number of buildings arrayed around a roughly oval common, which were mostly built in the middle of the 19th century. Later development was significantly reduced because the area was bypassed by the railroads. The common was laid out in 1728, when the area was first settled by colonists, and is enclosed by an 1845 fence built out of granite posts and wooden rails. Prominent buildings surrounding the common include the 1863 Italianate Unitarian Church, the 1833 Greek Revival Congregational Church, and the 1805 Federal style Grafton Inn.The district was added to the National Register of Historic Places in 1988.

Grafton is a town in Worcester County, Massachusetts, United States. The population was 19,664 at the 2020 census. The town consists of the North Grafton, Grafton, and South Grafton geographic areas, each with a separate ZIP Code. Incorporated in 1735, the town is home to a Nipmuc village known as Hassanamisco Reservation, the Willard House and Clock Museum, Community Harvest Project, and the Tufts University Cummings School of Veterinary Medicine. Grafton operates the state's largest on-call fire department, with 74 members.

The Quinsigamond River is a river in central Massachusetts. It is a tributary of the Blackstone River and ultimately drains into Narragansett Bay. Although the Quinsigamond has many small tributaries and drains a sizable area, the river proper is only 5.6 miles (9.0 km) long. It flows roughly southwards from its origin at Lake Quinsigamond at Worcester's eastern edge, past North Grafton where Bummet Brook enters, through Lake Ripple northwest of Grafton, and into Fisherville Pond at Fisherville, where it merges into the Blackstone River.

Farnumsville Historic District is a historic district encompassing a historic mill village in Grafton, Massachusetts. It is located on the eastern bank of the Blackstone River, extending along Providence and Main Streets, roughly between Cross and Depot Streets, and radiating along those roads and adjacent streets. This area was one of Grafton's 19th century industrial mill villages, which was centered on the Farnum Mill, which first began operating in the second decade of the 19th century. The main mill building that survives dates to 1844, and the housing stock in the village is in a diversity of styles, built roughly between the 1820s and 1920s.The district was added to the National Register of Historic Places in 1996.

Grafton High School is a high school in Grafton, Massachusetts, United States. The school has an enrollment size of approximately 900 students in grades 9–12. The curriculum offers a wide variety of courses in areas of business and computer science, music, video game design, English, family consumer science, health, physical education, mathematics, science and technology, social studies, special education, visual and performing arts, world languages, community service, school service, and independent studies.

The Fisherville Historic District is a historic district encompassing one of the four 19th century industrial villages of Grafton, Massachusetts. The area's first industrial activity was in 1831–2, when Peter Farnum (who had a mill at Farnumsville) and business partners built a brick mill there. A densely packed residential area grew around the mill complex, which achieved its present configuration c. 1909. The largest period of growth in terms of residential housing was in the last two decades of the 19th century, when a significant number of Italianate and Queen Anne worker houses were built.The district was listed on the National Register of Historic Places in 1996.

The Willard House and Clock Museum is a museum located in North Grafton, Massachusetts, United States.

The Cummings School of Veterinary Medicine of Tufts University is a graduate school of veterinary medicine located in North Grafton, Massachusetts. The Cummings School is the only college of veterinary medicine in New England. The school is also part of the Higher Education Consortium of Central Massachusetts.

Grafton State Hospital was a psychiatric hospital in Grafton, Massachusetts that operated from 1901 to 1973. Today, the site has been redeveloped with Tufts University's Cummings School of Veterinary Medicine as a major occupant, along with the Grafton Job Corps office and various other State agencies.Because of its significance in the history of the treatment of the mentally ill and its layout and institutional architecture, the hospital area was accepted to the National Register of Historic Places in 1994.