Hard Rock Hotel & Casino Biloxi

The Magnolia Hotel was built in 1847 to serve as a lodging establishment. It is thought to be the oldest surviving hotel on the Mississippi Gulf Coast. The hotel was added to the National Register of Historic Places in 1973, and was designated a Mississippi Landmark in 1985.

The U.S. Post Office, Courthouse, and Customhouse in Biloxi, Mississippi, also known as Biloxi City Hall, was built in 1908. It was designed by James Knox Taylor in Classical Revival style. It served as a courthouse and as a post office, and was listed on the National Register of Historic Places in 1978, when it was being used as Biloxi's city hall. It served the United States District Court for the Southern District of Mississippi during 1908–1959. Its first floor was renovated in 1960 and 1964 to be used as City Hall.

Redding House is a historic house in Biloxi, Mississippi, U.S.. It was built in 1908 for Charles Redding, a local businessman. It was designed in the Classical Revival architectural style. It has been listed on the National Register of Historic Places since May 18, 1984.

Beau Rivage is a waterfront casino resort in Biloxi, Mississippi, USA. It is owned by Vici Properties and operated by MGM Resorts International. The Beau Rivage hotel is the tallest building in Mississippi. The term 'Beau Rivage' is French for 'beautiful shore'; the original, well-known hotels of that name are the Beau-Rivage Geneva and Beau-Rivage Palace, both in Francophone Switzerland.

The Cathedral of the Nativity of the Blessed Virgin Mary, at 870 West Howard Avenue in Biloxi, Mississippi, is the seat of the Roman Catholic Diocese of Biloxi. It was designed by Theodore Brune and built by J.F. Barnes & Company of Greenville, Mississippi in 1902. The cathedral was added to the National Register of Historic Places in 1984. Brune was a German-American architect who designed several churches on the Gulf Coast of Louisiana. The Gothic design for the Blessed Virgin Mother Catholic Church on West Howard Avenue was constructed after the original church was destroyed by the Great Biloxi Fire of November 1900 on the same site. Stained glass windows were donated to the church by Julia Dulion Lopez (1857-1918) in memory of her late husband in early 1906. The windows were built by Reis and Reis of Munich, Germany and installed by Frederick Thornley of New York.

MGM Park is a baseball park in Biloxi, Mississippi. The home of the Double-A Biloxi Shuckers of the Southern League, it opened on June 6, 2015, and can seat up to 6,067 people. The stadium was the site of the 2019 Southern League All-Star Game. Though primarily a venue for Minor League Baseball, it has been the home of the Conference USA baseball tournament since 2017. Concerts have also been held at the venue.

First Baptist Church is a Baptist church located in Biloxi, Mississippi. It is affiliated with the Southern Baptist Convention.

Biloxi station is a closed and unstaffed Amtrak intercity train station in Biloxi, Mississippi. There is no station building; there is only a covered platform. The station is across the street from the Biloxi Transit Center, which serves Coast Transit Authority and Greyhound buses. Amtrak service to Biloxi began with the Gulf Coast Limited, which operated between 1984 and 1985. The stop was reactivated on March 31, 1993 in service on the Sunset Limited. Damage to the rail line resulting from Hurricane Katrina in 2005 caused Amtrak to suspend service east of New Orleans, including at Biloxi.

The Tivoli Hotel was built in 1926-27 as a 6-story, T-shaped brick building in Second Renaissance Revival architectural style. The hotel was added to the National Register of Historic Places in 1984. In 2005, the structure was badly damaged during Hurricane Katrina and was subsequently demolished.

Tullis-Toledano Manor, also known as, the Toledano-Philbrick-Tullis House, was a red-clay brick mansion on the Mississippi Gulf Coast in Biloxi. It was considered an example of Greek Revival architecture. The mansion was added to the National Register of Historic Places in 1976 and was destroyed by Hurricane Katrina in 2005.

The Ohr–O'Keefe Museum Of Art is a non-profit art museum located in Biloxi, Mississippi, dedicated to the ceramics of George E. Ohr, the self-proclaimed "Mad Potter of Biloxi". The museum is named for ceramic artist George E. Ohr (1857–1918), as well as Annette O'Keefe, late wife of former Biloxi mayor Jeremiah Joseph O'Keefe III, who was instrumental in donating money and raising funds for the completion of the museum campus.

The Pleasant Reed House was a sidehall shotgun house in Biloxi, Mississippi on the National Register of Historic Places. It was built by Pleasant Reed (1854–1932), a former slave on a Mississippi farm who moved with his family to coastal Biloxi after the American Civil War. Reed, as a freedman, worked as a laborer and carpenter and earned the money to build his own house for his rapidly growing family. The house was saved by the Biloxi chapter of the Delta Sigma Theta sorority and added to the National Register in 1979. In 2003, the House was moved to the new Frank Gehry-designed campus of the Ohr-O'Keefe Museum Of Art, where it was restored and opened to the public for tours. On August 29, 2005, the House was destroyed by Hurricane Katrina. However, the original archival materials and photographs were saved by museum curators, and the museum's board of trustees voted to rebuild the Pleasant Reed House. The Pleasant Reed Interpretive Center, a replica of the original house, opened to the public on September 29, 2008. The center features exhibits on local African American history.