Venable Tobacco Company Prizery and Receiving Room

The Confederate Soldiers Monument (popularly known as "The Boys Who Wore Gray") was a memorial to the soldiers from Durham County who fought for the Confederate States of America in the American Civil War. The statue was seriously damaged by protestors and removed from public view on August 14, 2017.

Venable Tobacco Company Warehouse is a historic tobacco storage warehouse located at Durham, Durham County, North Carolina. It consists of three storage units: Unit 1 and Unit 2 were built in 1905 and Unit 3 in the 1910s. It is a two-story, brick structure and is an example of "slow burn" masonry and wood factory construction. The warehouse is located adjacent to the Venable Tobacco Company Prizery and Receiving Room, which collectively are the only structures that remain of a larger complex.It was listed on the National Register of Historic Places in 1985.

First Presbyterian Church is a historic Presbyterian church in Durham, North Carolina. Located in the Downtown Durham Historic District, it is the oldest Presbyterian congregation in the city.

Downtown Durham Historic District is a national historic district located at Durham, Durham County, North Carolina. The district encompasses 97 contributing buildings and 1 contributing structure in the central business district of Durham. The buildings primarily date from the first four decades of the 20th century and include notable examples of Colonial Revival, Italianate, and Art Deco architecture. Notable buildings include the St. Philip's Episcopal Church (1907), Trinity Methodist Episcopal Church (1880-1881), First Baptist Church (1926-1927), Durham County Courthouse (1916), Durham Auditorium (Carolina Theatre, 1920s), Tempest Building (1894, 1905), National Guard Armory (1934-1937), United States Post Office (1934), Trust Building (1904), First National Bank Building (1913-1915), Mechanics and Farmers Bank (1921), Johnson Motor Company showroom (1927), Hill Building (1935), Snow Building (1933), and S. H. Kress store.It was listed on the National Register of Historic Places in 1977.On August 14, 2017 a 15-foot-high statue of an armed Confederate patriot was torn down in front of the 1916 Durham County Courthouse by demonstrators. The destruction of the statue followed the 2017 Unite the Right rally in Charlottesville, Virginia where one counter-demonstrator was killed.

Trinity United Methodist Church is a historic Methodist church in Durham, North Carolina.

The Durham Performing Arts Center (often called the DPAC) opened November 30, 2008 as the largest performing arts center in the Carolinas at a cost of $48 million. The DPAC hosts over 200 performances a year including touring Broadway productions, high-profile concert and comedy events, family shows and the American Dance Festival. Operated under the direction of Nederlander and Professional Facilities Management (PFM), DPAC has twice been listed as the #1 performing arts organization in the Triangle region by the Triangle Business Journal. Construction of the DPAC was part of a larger plan to redevelop downtown Durham by the Capitol Broadcasting Company, and includes other nearby properties such as the American Tobacco Historic District, the Durham Bulls Athletic Park, and the studios of the CBC-owned Fox 50 TV station. Listed three times in the top 50 in Pollstar magazine's worldwide theater attendance ranking, in 2011 DPAC was the #1 U.S. Theater in the listing with a capacity under 4,000 and #4 ranked Theater among all U.S. Theaters. On August 16, 2016, the venue surpassed 3 million visitors since its opening.

The Pinhook is an LGBTQ-owned music venue in Durham, North Carolina. It is located on the first floor of 117 West Main Street in the Downtown Durham Historic District.

St. Philip's Episcopal Church is a historic Episcopal church in Durham, North Carolina. It is the oldest remaining church building in the Downtown Durham Historic District and is listed on the register of the Historic Preservation Society of Durham.

The Old North Carolina Mutual Life Insurance Company Building, also known as the Mechanics and Farmers Bank Building, is an office building at 114-116 West Parrish Street in downtown Durham, North Carolina. It formerly served as the headquarters for the North Carolina Mutual Life Insurance Company, which was formerly one of the nation's largest companies founded and owned by African-Americans. The building was declared a National Historic Landmark in 1975.

The City View Building, also known as 123 West Main Street and formerly known as the First National Bank of Durham, is a historic skyscraper in the Downtown Historic District in Durham, North Carolina. Since 2001, it has housed the national headquarters of the Center for Community Self-Help.

One City Center is a 27-story mixed-use tower located at 110 Corcoran Street in Downtown Durham, North Carolina, in the United States. One City Center is the tallest building in downtown Durham, and the second tallest in Durham behind University Tower. Completed in 2018, One City Center is partially leased to Duke University and WeWork.

The Durham County Justice Center is a civic building in downtown Durham, North Carolina. The $120 million building opened to the public in February 2013. The building houses the Durham County Sheriff's Office, the Durham County District Attorney's Office, and has 20 courtrooms. The building is 318,533 square feet and was built to LEED Gold Standards. The Justice Center was built with sustainable materials and includes lawns on its roofs for insulation and to capture runoff. It is one of the tallest buildings in Durham and dominates the downtown skyline from NC 147.