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The Skid Row City Limit Mural is an 18-by-50-foot (5.5 by 15.2 m) mural displayed on San Julian Street in Los Angeles, California. It features a map demarcating Skid Row's legally recognized boundaries alongside an official-looking sign, replete with city seal, reading "Skid Row City Limit, Population: Too Many." This is the initial installation of a mural project that will eventually cover the whole wall on the San Julian block just north of 6th Street (Closest address is 570 south San Julian street).Installed in compliance with the city's mural ordinance, the project was created and organized by Skid Row community activist General Jeff Page for his Issues and Solutions organization, with mural installation led by local street art crew Winston Death Squad. It was carried out solely with volunteer labor from Skid Row citizens and without the aid of any non-profit service organizations. The piece represents a reaction to the growing practice among commercial groups of referring to historic areas of Skid Row with alternative designations. An adjacent companion piece titled "Skid Row Map" emphasizes Skid Row's historic and official significance with a citation of the 2006 Jones v. City of Los Angeles court decision that specifies Skid Row's physical boundaries as between Main and Alameda streets to the west and east, and Third and Seventh streets to the north and south. Los Angeles City Councilman José Huizar's office has hailed the mural, saying, "It's community pride on the one hand, it's cleverly done and it creates conversation and debate, which often great public art does." In its annual street art review, LA Weekly named the Skid Row City Limit mural the city's best new street art mural of 2014.

Cole's Pacific Electric Buffet, also known as Cole's P.E. Buffet, is a restaurant and bar located at 118 East 6th Street in the Historic Core district of downtown Los Angeles, California, the oldest operating in Los Angeles at the same location since its founding. Cole's was founded in 1908 by Henry Cole on the ground floor of the Pacific Electric Building, which served as the main terminal for the Pacific Electric Railway. Cole's unique table tops were made from the varnished doors of retired Red Cars of the Pacific Electric Railway. The tables were removed as part of the renovation and were reportedly relocated to the developer's nearby corporate headquarters above Clifton's Cafeteria. The restaurant claims (along with Philippe's) that the first French dip sandwich was served at Cole's in the same year. Some have suggested that Philippe's is the original, as the sandwich was named "French" dip because of the original proprietor Philippe Mathieu's French heritage. However, according to carvers at Cole's, Henry Cole first dipped the French bread in jus at the request of a customer who had had recent dental work. The French bread was too hard and it hurt this customer's teeth, so Henry dipped the bread in order to soften it. Other customers, with perfectly good teeth, saw Henry dip the bread and requested that he do the same for them - and thus the French dip was born. Other theories exist, so debate is likely to continue. Henry Cole also operated Los Angeles's first check cashing service from the restaurant.Henry Cole was later arrested in 1942 by the Federal Government for fraud.Cole's was designated a Los Angeles Historic-Cultural Monument in 1989.The location resembles the bar from Who Framed Roger Rabbit, complete with reference to “French dip” on menu.

Fire Station No. 23 is a former fire station in Downtown Los Angeles. Built in 1910 as an operating fire station, it was also the Los Angeles Fire Department's headquarters until 1920 and the residence of every fire chief from 1910-1928. When it opened, it spawned a political firestorm due to the ornate interior and expensive imported materials, leading to its being called the "Taj Mahal" of firehouses. After 50 years of operation, the station was closed in 1960 as the department began replacing older stations with new facilities. Since the 1980s, Fire Station No. 23 has been a popular filming location. Motion pictures filmed at the station include the Ghostbusters movies, The Mask, Police Academy 2, Flatliners, Firehouse and National Security.

The historic Pacific Electric Building (also known as the Huntington Building, after the railway’s founder, Henry Huntington, or simply “6th & Main”), opened in 1905 in the core of Los Angeles as the main train station for the Pacific Electric Railway, as well as the company's headquarters; Main Street Station served passengers boarding trains for the south and east of Southern California. The building was designed by architect Thornton Fitzhugh. Though not the tallest in Los Angeles, its ten floors enclosed the greatest number of square feet in any building west of Chicago for many decades. Above the train station, covering the lower floors, were five floors of offices; and in the top three was the Jonathan Club, one of the city's leading businessmen's clubs introduced by magnates from the Northeast. After the “Great Merger” of Pacific Electric into Southern Pacific Railroad in 1911, the PE Building became the home of Southern Pacific in Los Angeles. In 1925, a second electric rail hub, the Subway Terminal, was opened near Pershing Square to serve the north and west.

Nickel Diner is a Los Angeles, California, restaurant known for its versions of diner food including dishes a maple-glaze bacon doughnut, baked eggs, steak sandwich, and catfish.

The Union Rescue Mission, commonly abbreviated as the URM, is a Christian homeless shelter in the Skid Row neighborhood of Los Angeles, California. It is the oldest in the city and the largest private homeless shelter in the United States. The organization behind the URM is a 501(c)(3) nonprofit that was established in 1891.

The Weingart Center for the Homeless is a comprehensive human services center for homeless men and women living in Skid Row, Los Angeles. It provides on-site short and long-term services including transitional residential housing, medical & mental health, permanent supportive housing, substance abuse recovery, education, workforce development, long term case management. The Weingart Center is a 501(c)(3) non-profit.The Weingart Center for the Homeless has five facilities in one block, plus a walk-in access center, totaling 170,000 sq. ft. the Weingart Center serves 6000 homeless people and provides 253,000 meals annually. The Weingart Center is located at 566 South San Pedro Street in the building that was once the El Rey Hotel, designed in 1923 by architect Charles F. Whittlesey.

The Garment Capitol Building is a historic building in Los Angeles. Its developer was Florence Casler. It was designed in the Gothic Revival architectural style by William Douglas Lee, and it was completed in 1926. It has been listed on the National Register of Historic Places since March 8, 2010. It was acquired by developer Naty Saidoff in 2012, who invested US$20 million to restore it.

On February 19, 2013, the body of Canadian tourist Elisa Lam (born as Lam Ho-yi; Chinese: 藍可兒) was recovered from a large cistern atop the Stay on Main hotel in Downtown Los Angeles, where she had been a guest. She was last seen alive on January 31 and was reported missing by her parents on February 8. Her body was discovered by a hotel maintenance worker investigating complaints of flooding and low water pressure. Interest in Lam's disappearance increased on February 13 when the Los Angeles Police Department released security camera footage of her behaving erratically in a hotel elevator on the day she was last seen alive. The video went viral. While an autopsy performed on February 21 was inconclusive in determining the manner of Lam's death, the Los Angeles County Coroner's office subsequently ruled the death an accident with bipolar disorder being a significant contributing factor. Guests at the Stay on Main sued the hotel over the incident and Lam's parents filed a separate suit later that year; the latter was dismissed in 2015. Some of the early Internet interest noted what were considered to be unusual similarities between Lam's death and the 2002 horror film Dark Water. The case has since been referenced in international popular culture and been the subject of several creative works.

The Hotel Rosslyn Annex is a historic building in Los Angeles, California built in 1923 at the corner of 5th and Main streets. The structure was designed by the firm Parkinson & Parkinson in the Beaux Arts style and listed on the National Register of Historic Places in 2013.The building is across the street from the original 800-room Rosslyn Hotel built in 1914. Designed as a twin, both were topped by mammoth glowing signs featuring the names surrounded by a heart, the shape acknowledging the Hart brothers who owned the hotels.The 264-unit Hotel Rosslyn Annex was renovated in 2015 to house a mix of homeless veteran, low-income and market-rate tenants.

The Regent Theatre is a live music venue and historic former movie theater in the Downtown section of Los Angeles, California. Opened as the National Theatre in 1914, it is the oldest remaining theater building on South Main Street. Following its initial status as a first-run filmhouse, it began screening second-run programming in the 1920s amidst a widespread decline of the vicinity's entertainment scene in favor of the newer Broadway Theater District. After serving as a grindhouse, the Regent was later converted to an adult movie theater before shuttering in 2000. Upon the completion of renovations, the facility was reopened as a concert venue in 2014; Live Nation became the operator in 2019.

Textile Center Building is a 12-story Gothic Revival and Italian Renaissance Revival architectural styled brick building located in the Los Angeles Fashion District. Designed by William Douglas Lee in the Gothic Revival style, the building opened in 1926 as a center for garment manufacturing. It has since been converted to condominiums.