Klaus von Nichtssagend Gallery

339 Grand Street, also addressed as 57 Ludlow Street, located at the corner of Ludlow Street in the Lower East Side neighborhood of Manhattan, New York City was completed in c. 1831–1833 in the Federal style as one of five row houses constructed by John Jacob Astor on property he purchased in 1806. The early tenants of the building were several dry goods merchants. The rear addition on Ludlow Street was built c.1855. The front of the house has been a storefront since at least 1884.The house, a rare example of a surviving Federal-style house in Manhattan, is the only one of the five row houses built by Astor that is still largely intact. It features "a front facade with Flemish bond brickwork, high peaked roof and dormer", and the rear retains its "flat roof, stone lintels and sills, and cornice." The house is 3.5 stories in height in the front – three in the rear – and is 17 feet (5.2 m) wide.The house was designated a New York City landmark by the New York City Landmarks Preservation Commission on October 29, 2013.

Gertel's Bakery was a kosher bake shop on New York's Lower East Side. Located at 53 Hester Street, Gertel's Bakery operated from 1914 until the retail store closed on June 21, 2007. It merged with Delancey Bakery and its successor operates as Gertel's Uptown, 101 Steuben Street, Brooklyn, NY, providing wholesale business only.

Shin Gallery is an encyclopedic art gallery owned by Hong Gyu Shin. It specializes in modern and contemporary art and hosts museum-quality exhibitions. It is located on the Lower East Side of Manhattan, New York, and opened in 2013. In 2014, an immersive project space was opened next to the gallery. In 2017 Shin Gallery expanded to include three different gallery spaces on Orchard Street. In 2020 Shin Haus was launched, a program with the aim of discovering up-and-coming artists. Shin Gallery also specializes in rediscovering overlooked artists, traditionally marginalized due to their ethnicity and gender. Work is also done with a variety of venues including national heritage sites, hotels, and public spaces further demonstrating its international agenda.

Kossar's Bialys (Kossar's Bialystoker Kuchen Bakery) located at 367 Grand Street (and Essex Street), on the Lower East Side in Manhattan, New York City, is the oldest bialy bakery in the United States.

Foley Gallery is a contemporary art gallery in Manhattan, New York City, owned by Michael Foley. Since opening in 2004, Foley Gallery has moved from the Chelsea neighborhood to the Lower East Side in 2014. Among the artists Foley represents are Joseph Desler Costa, Wyatt Gallery, Sage Sohier, Martin Klimas, Simon Schubert, Henry Leutwyler and Ina Jang. Foley has previously shown work by Rosalind Solomon, Polixeni Papapetrou, Rachell Sumpter and Hank Willis Thomas.

The Ludlow Street Jail was New York City's Federal prison, located on Ludlow Street and Broome Street in Manhattan. Some prisoners, such as soldiers, were held there temporarily awaiting extradition to other jurisdictions, but most of the inmates were debtors imprisoned by their creditors. Seward Park Campus now sits on the site of the jail.The jail was completed in June 1862 constructed of Philadelphia brick ornamented with New Jersey freestone trimmings. The facility contained 87 cells, each about 100 square feet. Long, barred windows provided light and air that was ahead of its time.

Orchard was an artist-run exhibition and event space located at 47 Orchard Street in New York's Lower East Side from 2005-2008. The gallery was run as a for-profit limited liability corporation founded for the project. The partners included artists, filmmakers, critics, art historians, and curators. Orchard was among early contemporary art projects and galleries that moved onto Orchard and generally the Lower East Side below Delancey Street along with Miguel Abreu Gallery, Reena Spaulings, and Scorched Earth. Brandon Joseph noted, "the Orchard 'project' treaded a fine—and perhaps ultimately impossible—line between self-reflexivity and (to use a barbaric neologism) self-complicity, which could veer at times into self-promotion." Orchard's program focused on, "thematically, conceptually and politically driven group exhibitions and projects," according to the space's website.Orchard restaged or produced unrealized projects by Michael Asher, Andrea Fraser with Allan McCollum, Dan Graham, and Lawrence Weiner. Orchard has also presented historical works by Daniel Buren, Luis Camnitzer, Juan Downey, Hans Haacke, Roberto Jacoby, Adrian Piper, Anthony McCall and Martha Rosler, as well as new works by Martin Beck, Merlin Carpenter, Nicolás Guagnini, Jutta Koether, Josiah McElheny, Lucy McKenzie, Blake Rayne, Stephan Pascher, Jeff Preiss, R. H. Quaytman, Karin Schneider, and Jason Simon, among others.

Miguel Abreu Gallery is a contemporary art gallery with two locations in New York City.

Guss' Pickles was founded by a Polish immigrant, Isidor Guss. Guss arrived in New York in 1910, and like hundreds of thousands of other Jewish immigrants, settled in the Lower East Side. Clustered in the "pickle district" of Essex and Ludlow streets, early 20th century pickle vendors gave birth to what would be known as "New York style" pickles. Guss at first worked for L. Hollander and Sons, before opening his own store. At the time, the neighborhood was teeming with 80 other pickle shops. However, immigration restrictions, a ban on pushcarts and the steady economic decline of the Lower East Side felled almost all of these shops. Guss' Pickles withstood the economic difficulty and now remains as the last store from the days of the Essex Street empire. In 1979, Harry Baker and his partner Burt Blitz took over Guss' Pickles. Through the 1980s and into the 2000s, Baker and his son Tim ran the store. .Guss' Pickles was featured in the film Crossing Delancey. Guss' Pickles ships gallon size nationwide at their official web-site GussPickles.com. In June 2017 Guss' Pickles opened a new store in Brooklyn inside the Dekalb Market Hall.

Catinca Tabacaru Gallery is a contemporary art gallery in New York City opened in May 2014. Catinca Tabacaru Gallery, Harare, the Gallery's second location was founded in August 2017 in partnership with Dzimbanhete Arts Interactions.

Dirt Candy is a vegetarian restaurant in the Lower East Side neighborhood of Manhattan in New York City. Chef and owner Amanda Cohen opened the restaurant in a small East Village space in 2008, and moved to its present location in 2015. It has received critical attention for its creative dishes which often focus on a single vegetable.

Grand Street was a local station on the demolished IRT Second Avenue Line in Manhattan, New York City. It had two levels. The lower level had two tracks and two side platforms and the upper level had one track that served the express trains. The next stop to the north was Rivington Street. The next stop to the south was Canal Street. The station closed on June 13, 1942.