Center for Cell and Gene Therapy

Houston Orthopedic and Spine Hospital is the number one rated hospital in Houston for surgery according to Consumer Reports. Located in Bellaire, Texas, it was originally Foundation Medical Hospital but then changed its name to Houston Orthopedic and Spine Hospital. The building next to the hospital is still called Foundation Medical Tower. Commonly known as HOSH, it is a specialized orthopedic hospital with some teaching involved. HOSH sometimes takes residents and allows them to view surgeries and learn about the profession. HOSH is one of the most well-recognized hospital in the city, state, and nation. Houston Orthopedic and Spine hospital has well-known physicians and services that provide the best in medical care.

Houston Methodist Hospital is the flagship quaternary care hospital of Houston Methodist academic medical center. Located in the Texas Medical Center in Houston, Texas, Houston Methodist Hospital was established in 1919 during the height of the Spanish influenza epidemic as an outreach ministry of Methodist Episcopal Church. Houston Methodist comprises eight hospitals, an academic institute, a primary care group, and more than 300 locations throughout greater Houston. The hospital has consistently ranked as "One of America's Best Hospitals" according to U.S. News & World Report. The hospital has earned worldwide recognition in multiple specialties including cardiovascular surgery, cancer, epilepsy treatment and organ transplantation.Houston Methodist System changed its official name to Houston Methodist in 2013.

The Texas Medical Center (TMC) is a 2.1-square-mile (5.4 km2) medical district and neighborhood in south-central Houston, Texas, United States, immediately south of the Museum District and west of Texas State Highway 288. Over 60 medical institutions, largely concentrated in a triangular area between Brays Bayou, Rice University, and Hermann Park, are members of the Texas Medical Center Corporation—a non-profit umbrella organization—which constitutes the largest medical complex in the world. The TMC has an extremely high density of clinical facilities for patient care, basic science, and translational research.The Texas Medical Center employs over 106,000 people, hosts 10 million patient encounters annually, and has a gross domestic product of US$25 billion. Over the decades, the TMC has expanded south of Brays Bayou towards NRG Park, and the organization has developed ambitious plans for a new "innovation campus" south of the river. The 4.93-square-mile (12.8 km2) Medical Center / Astrodome area, highly populated with medical workers, is home to over 20,000 people.The TMC is served by the METRORail Red Line, a north-south light rail route which connects the district to Downtown Houston and NRG Park.

The Texas Heart Institute is an independent, nonprofit organization that is improving cardiovascular health through trailblazing research, thought leadership, education, and patient care to forge a better future for those with cardiovascular disease—a future with an increased focus on preventive cardiology. Located within the Texas Medical Center in Houston, Texas, and founded in 1962 by renowned cardiac surgeon Dr. Denton A. Cooley, The Texas Heart Institute performed the first successful heart transplant and total artificial heart implant in the United States. Its physicians and surgeons remain recognized as worldwide leaders in the diagnosis and treatment of even the most complex cardiovascular conditions performing more than 118,800 open heart operations, 258,000 cardiac catheterizations, and 1,500 heart transplants, and The Texas Heart Institute at Baylor St. Luke’s Medical Center has been ranked among the top cardiovascular centers in the United States by U.S. News & World Report for more than 30 years.Today The Institute is led by Dr. Joseph G. Rogers, an internationally recognized cardiologist and highly published thought leader in heart transplantation and mechanically assisted circulation.

Baylor St. Luke's Medical Center (BSLMC) is the private adult teaching hospital of Baylor College of Medicine jointly owned with CHI St. Luke's Health. The medical staff at the hospital includes full-time Baylor faculty, as well as community physicians. The hospital was formerly known as St. Luke's Episcopal Hospital before its acquisition by Catholic Health Initiatives in 2013 and subsequent co-ownership agreement with Baylor in 2014. It is located on Bertner Avenue in the Texas Medical Center in Houston. The hospital is an 881-bed institution that is also a clinical partner of the Texas Heart Institute.

The University of Texas MD Anderson Cancer Center (colloquially MD Anderson Cancer Center) is a comprehensive cancer center in Houston, Texas. It is the largest cancer center in the U.S. and one of the original three comprehensive cancer centers in the country. It is both a degree-granting academic institution and a cancer treatment and research center located at the Texas Medical Center in Houston. It is affiliated with The University of Texas Health Science Center at Houston. According to Newsweek, MD Anderson Cancer Center is considered the best hospital in the world for oncology and related cancer treatment.

Texas Children's Hospital is a nationally ranked, freestanding 973-bed, acute care women's and children's hospital located in Houston, Texas. It is the primary pediatric teaching hospital affiliated with Baylor College of Medicine and is located within the Texas Medical Center. The hospital provides comprehensive pediatric specialty and subspecialty care to infants, children, teens, and young adults aged 0–21 throughout Texas and features an ACS verified level I pediatric trauma center. Its regional pediatric intensive-care unit and neonatal intensive care units serve the Southern United States region and also has programs to serve children from around the world. With 973 beds, it is the largest children's hospital in the United States.In addition to its main site in the Texas Medical Center, Texas Children's Hospital has satellite campuses in the suburb of The Woodlands and at its West Campus near Houston's Energy Corridor neighborhood. Texas Children's also has a network of clinics throughout the Houston metropolitan area and maintains partnerships with sites across the world through the Texas Children's Global Health Network.Texas Children's Hospital is ranked as one of the best children's hospitals in the country and the world. The 2023-2024 edition of U.S. News & World Report ranked Texas Children's Hospital #3 amongst 200 pediatric hospitals in the nation, and it has been recognized on the U.S. News & World Report Honor Roll for fifteen consecutive years.

The Texas Medical Center (TMC) Library is a health sciences library located in the Texas Medical Center (TMC) in Houston, TX. The TMC Library is the only major medical and scientific library serving the entire 1,345 sq. acre Texas Medical Center (TMC) campus and its non-profit institutions. It offers librarian services, and provides biomedical information for education and research activities to take place, and study space for students for these schools to help maintain their accreditation. Additionally, for the past twenty-five years, the TMC Library has been the home site for the National Network of Libraries of Medicine – South Central Region (NN/LM SCR). Through a competitive bid process, the TMC Library has secured the contract from the National Library of Medicine, under the National Institutes of Health.

The University of Texas Police at Houston (UT Police at Houston) is a full-service Police Department that serves the communities of the University of Texas Health Science Center at Houston (UTHealth) and the M.D. Anderson Cancer Center. UT Police at Houston patrols the Texas Medical Center and has property in surrounding counties.

Wendel D. Ley Track and Holloway Field is a stadium in Houston, Texas. It is primarily used for track and field and soccer for the Rice University Owls. It is bounded by Main Street (southeast), University Boulevard (southwest), Reckling Park baseball field (west) and open athletic fields (north). The stadium sits on the location of Rice Field, Rice's old football stadium which opened in 1913 and was used until the opening of Rice Stadium in 1950. (Games in 1912 had been played at West End Park). The venue held less than 37,000 people for football. Today, it holds approximately 5,000 people. Part of the grandstand from the visitor's side of the old football stadium is used as the current grandstand, although the bleachers were removed. Today, there are about 100 permanent seats on the stone terracing. The soccer field was installed in 2000-2001 after Rice added women's soccer as a varsity sport. In October 2002, the stadium hosted a WUSA exhibition match between the Washington Freedom (featuring Mia Hamm) and the Atlanta Beat. The event set the current stadium record with more than 5,000 tickets sold. The stadium hosted another WUSA exhibition in 2003 and has hosted two conference soccer tournaments: the Western Athletic Conference Tournament in 2002 and the Conference USA Tournament (won by Rice) in 2005. The WAC Outdoor Track & Field Championships were held there in 2002 and again in 2004. Following Rice's move to Conference USA in 2005, the C-USA Outdoor Track & Field Championships were hosted at the facility in 2007. The stadium has also served as a practice venue for soccer teams visiting Houston, including the United States men's national team, Everton of the Premier League, the Colorado Rapids, the Republic of Ireland women's national football team, and the Argentina men's national football team. The stadium has also hosted a series of summer all-comer track and field meets for more than 20 years, and notable athletes including Carl Lewis, Michael Johnson, Joanna Hayes and Bryan Bronson have competed.

The Jane and Robert Cizik School of Nursing at the University of Texas Health Science Center in Houston (UTHealth) is an American nursing education institution. The school has graduated more than 12,000 nurses since its establishment in 1972. Its name was changed to the Jane and Robert Cizik School of Nursing at UTHealth in 2017 in recognition of a gift of $25 million that endowed scholarships, faculty chairs, and research in addition to a distinguished lecture series. Located in the Texas Medical Center, Cizik School of Nursing's building, which also serves as a student community center for the UTHealth campus, opened in October 2004 and was awarded LEED Gold certification by the U.S. Green Building Council in 2009.

The Houston Main Building (HMB) formerly the Prudential Building, was a skyscraper in the Texas Medical Center, Houston, Texas. It originally housed offices of the Prudential Insurance Company, before becoming a part of the MD Anderson Cancer Center. The building was demolished on January 8, 2012. It was designed by Kenneth Franzheim.