MD Anderson Cancer Center

The University of Texas Police at Houston (UT Police at Houston) is a full-service Police Department that serves the communities of the University of Texas Health Science Center at Houston (UTHealth) and the M.D. Anderson Cancer Center. UT Police at Houston patrols the Texas Medical Center and has property in surrounding counties.

The Texas Medical Center (TMC) is a 2.1-square-mile (5.4 km2) medical district and neighborhood in south-central Houston, Texas, United States, immediately south of the Museum District and west of Texas State Highway 288. Over 60 medical institutions, largely concentrated in a triangular area between Brays Bayou, Rice University, and Hermann Park, are members of the Texas Medical Center Corporation—a non-profit umbrella organization—which constitutes the largest medical complex in the world. The TMC has an extremely high density of clinical facilities for patient care, basic science, and translational research.The Texas Medical Center employs over 106,000 people, hosts 10 million patient encounters annually, and has a gross domestic product of US$25 billion. Over the decades, the TMC has expanded south of Brays Bayou towards NRG Park, and the organization has developed ambitious plans for a new "innovation campus" south of the river. The 4.93-square-mile (12.8 km2) Medical Center / Astrodome area, highly populated with medical workers, is home to over 20,000 people.The TMC is served by the METRORail Red Line, a north-south light rail route which connects the district to Downtown Houston and NRG Park.

The Texas Heart Institute is an independent, nonprofit organization that is improving cardiovascular health through trailblazing research, thought leadership, education, and patient care to forge a better future for those with cardiovascular disease—a future with an increased focus on preventive cardiology. Located within the Texas Medical Center in Houston, Texas, and founded in 1962 by renowned cardiac surgeon Dr. Denton A. Cooley, The Texas Heart Institute performed the first successful heart transplant and total artificial heart implant in the United States. Its physicians and surgeons remain recognized as worldwide leaders in the diagnosis and treatment of even the most complex cardiovascular conditions performing more than 118,800 open heart operations, 258,000 cardiac catheterizations, and 1,500 heart transplants, and The Texas Heart Institute at Baylor St. Luke’s Medical Center has been ranked among the top cardiovascular centers in the United States by U.S. News & World Report for more than 30 years.Today The Institute is led by Dr. Joseph G. Rogers, an internationally recognized cardiologist and highly published thought leader in heart transplantation and mechanically assisted circulation.

The Jane and Robert Cizik School of Nursing at the University of Texas Health Science Center in Houston (UTHealth) is an American nursing education institution. The school has graduated more than 12,000 nurses since its establishment in 1972. Its name was changed to the Jane and Robert Cizik School of Nursing at UTHealth in 2017 in recognition of a gift of $25 million that endowed scholarships, faculty chairs, and research in addition to a distinguished lecture series. Located in the Texas Medical Center, Cizik School of Nursing's building, which also serves as a student community center for the UTHealth campus, opened in October 2004 and was awarded LEED Gold certification by the U.S. Green Building Council in 2009.

Baylor St. Luke's Medical Center (BSLMC) is the private adult teaching hospital of Baylor College of Medicine jointly owned with CHI St. Luke's Health. The medical staff at the hospital includes full-time Baylor faculty, as well as community physicians. The hospital was formerly known as St. Luke's Episcopal Hospital before its acquisition by Catholic Health Initiatives in 2013 and subsequent co-ownership agreement with Baylor in 2014. It is located on Bertner Avenue in the Texas Medical Center in Houston. The hospital is an 881-bed institution that is also a clinical partner of the Texas Heart Institute.

The Center for Cell and Gene Therapy is a translational research institute within Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital, all of which are located in the Texas Medical Center in Houston, Texas. The center's mission is to develop novel therapies for a range of diseases through collaboration between basic research laboratories and clinical departments. The center was founded by Dr. Malcolm K. Brenner in 1998 and includes six major parts. The current director is Dr. Helen E. Heslop, physician-scientist who specializes in translational research. The Center for Cell and Gene Therapy conducts research into numerous diseases, including but not limited to pediatric cancers, diabetes, HIV, glioma and cardiovascular disease. The center has laboratory space in both Baylor College of Medicine and Texas Children's Hospital, and clinical units in Texas Children's and Methodist Hospitals.The Texas Children's Hospital is home to the center's Translational Research Labs and Good Manufacturing Practice (GMP) Laboratories. The Center for Cell and Gene Therapy has the largest academic GMP facility in the world, with 8,600 square feet of Class 10,000 (ISO7) cleanroom space. The GMP Gene Vector Lab produces clinical grade vectors for use in Phase I/II trials, while the GMP Clinical Research Lab prepares patient components for clinical trials. The Gene Vector Lab was one of only three National Gene Vector Laboratories until that entity was replaced by the National Gene Vector Biorepository in 2008. The Research Lab is a member of the Production Assistance for Cell Therapies (PACT).The Stem Cell Transplantation Program has two units. The pediatric unit has more than 16,000 square feet on the eighth floor of Texas Children's Hospital's West Tower. The 30,000-square foot adult unit is in The Methodist Hospital's Main Tower.

The UTHealth School of Public Health is one of six component institutions of the University of Texas Health Science Center at Houston. The Texas Legislature authorized the creation of a school of public health in 1947, but did not appropriate funds for the school until 1967. The first class was admitted in the fall of 1969, doubled in the second year and doubled again in the third year, with continued growth over the years since. UTHealth brings together the School of Public Health, with the Medical School, the School of Nursing, the School of Dentistry, the Graduate School of Biomedical Sciences, the School of Biomedical Informatics, and the UT Harris County Psychiatric Center.The school's main campus is located in Houston's famed Texas Medical Center. It originally occupied rented and borrowed space in the Medical Center but today it occupies its own building plus regional campuses in San Antonio, El Paso, Dallas, Brownsville, and Austin.

Houston Orthopedic and Spine Hospital is the number one rated hospital in Houston for surgery according to Consumer Reports. Located in Bellaire, Texas, it was originally Foundation Medical Hospital but then changed its name to Houston Orthopedic and Spine Hospital. The building next to the hospital is still called Foundation Medical Tower. Commonly known as HOSH, it is a specialized orthopedic hospital with some teaching involved. HOSH sometimes takes residents and allows them to view surgeries and learn about the profession. HOSH is one of the most well-recognized hospital in the city, state, and nation. Houston Orthopedic and Spine hospital has well-known physicians and services that provide the best in medical care.

Houston Methodist Hospital is the flagship quaternary care hospital of Houston Methodist academic medical center. Located in the Texas Medical Center in Houston, Texas, Houston Methodist Hospital was established in 1919 during the height of the Spanish influenza epidemic as an outreach ministry of Methodist Episcopal Church. Houston Methodist comprises eight hospitals, an academic institute, a primary care group, and more than 300 locations throughout greater Houston. The hospital has consistently ranked as "One of America's Best Hospitals" according to U.S. News & World Report. The hospital has earned worldwide recognition in multiple specialties including cardiovascular surgery, cancer, epilepsy treatment and organ transplantation.Houston Methodist System changed its official name to Houston Methodist in 2013.

TIRR Memorial Hermann (the four initials stand for "The Institute for Rehabilitation and Research") is a 134-bed rehabilitation hospital, rehabilitation and research center, outpatient medical clinic and network of outpatient rehabilitation centers in Houston, Texas that offers physical rehabilitation to patients following traumatic brain or spinal injury or to those suffering from neurologic illnesses.TIRR Memorial Hermann's main campus offers inpatient rehabilitation in the Texas Medical Center in Houston, Texas. There are 5 outpatient rehabilitation locations in the greater Houston area, including Kirby Glen, Memorial City, Greater Heights, Sugar Land, and The Woodlands. TIRR Memorial Hermann is a teaching hospital for Baylor College of Medicine and University of Texas Health Science Center at Houston.

Texas Children's Hospital is a nationally ranked, freestanding 973-bed, acute care women's and children's hospital located in Houston, Texas. It is the primary pediatric teaching hospital affiliated with Baylor College of Medicine and is located within the Texas Medical Center. The hospital provides comprehensive pediatric specialty and subspecialty care to infants, children, teens, and young adults aged 0–21 throughout Texas and features an ACS verified level I pediatric trauma center. Its regional pediatric intensive-care unit and neonatal intensive care units serve the Southern United States region and also has programs to serve children from around the world. With 973 beds, it is the largest children's hospital in the United States.In addition to its main site in the Texas Medical Center, Texas Children's Hospital has satellite campuses in the suburb of The Woodlands and at its West Campus near Houston's Energy Corridor neighborhood. Texas Children's also has a network of clinics throughout the Houston metropolitan area and maintains partnerships with sites across the world through the Texas Children's Global Health Network.Texas Children's Hospital is ranked as one of the best children's hospitals in the country and the world. The 2023-2024 edition of U.S. News & World Report ranked Texas Children's Hospital #3 amongst 200 pediatric hospitals in the nation, and it has been recognized on the U.S. News & World Report Honor Roll for fifteen consecutive years.

The Houston Main Building (HMB) formerly the Prudential Building, was a skyscraper in the Texas Medical Center, Houston, Texas. It originally housed offices of the Prudential Insurance Company, before becoming a part of the MD Anderson Cancer Center. The building was demolished on January 8, 2012. It was designed by Kenneth Franzheim.