Franciscan Health Lafayette Central

Park Mary Historic District is a national historic district located at Lafayette, Tippecanoe County, Indiana. The district encompasses 106 contributing buildings and 1 contributing structure in a predominantly residential section of Lafayette. It developed between about 1853 and 1950 and includes representative examples of Italianate, Queen Anne, and Bungalow / American Craftsman style architecture. Notable contributing buildings include the Thomas Hull House (1870), Fry House (1873), Perrin House (1868), Fletmeyer House (1881), Keipner House (1885), Behm House (1858), Greagor House (1873), Ulrick House, John and William Levering House (1858), Sawyer House (1868), Lafayette Christian Reformed Church (1929), Lincoln School (1923), and Lafayette Armory (1927).It was listed on the National Register of Historic Places in 2001.

Perrin Historic District is a national historic district located at Lafayette, Tippecanoe County, Indiana. The district encompasses 173 contributing buildings and 2 contributing structures in a predominantly residential section of Lafayette. It developed between about 1869 and 1923 and includes representative examples of Italianate, Queen Anne, Colonial Revival, Stick Style / Eastlake movement, and Bungalow / American Craftsman style architecture. Notable contributing buildings include the James Perrin House (1869, c. 1890), John Heinmiller House (c. 1885), James H. Cable House (c. 1898), Adam Herzog House (1878), Coleman-Gude House (1875), Frank Bernhardt House (1873), August Fisher Cottage (c. 1910), John Beck House (1887), an William H. Sarles Bungalow (1923).It was listed on the National Register of Historic Places in 1979.

Waldron–Beck House and Carriage House is a historic home and carriage house located at Lafayette, Tippecanoe County, Indiana. The house was built in 1877, and is a two-story, irregularly shaped Italianate style brick dwelling, with a rear service wing. It sits on a stone foundation and has a multi-hipped roof with bracketed cornice. It features a three-sided, two-story projecting bay. The carriage house is a two-story, three bay brick building. It has a hipped roof with cupola and a bracketed cornice.: 2–3 It was listed on the National Register of Historic Places in 1984.

Jefferson Historic District is a national historic district located at Lafayette, Tippecanoe County, Indiana. The district encompasses 161 contributing buildings, 2 contributing sites, and 22 contributing structures in a predominantly residential section of Lafayette. It developed between about 1853 and 1951 and includes representative examples of Italianate, Greek Revival, and Bungalow / American Craftsman style architecture. Notable contributing resources include the Deutsche Evangelische Kirche (1905), Isador Metzger House (c. 1866), Hubert Gilmartin House (c. 1868), B.F. Biggs Pump Factory Building (1872, 1885–1894), Deutsche Methodist Kirche (1885), Herman & Mary Fletemeyer House (c. 1897), Mohr House (c. 1865), Warrenberg-Reule Double House (c. 1878), Alfred Gaddis House (c. 1865), Wabash Valley House (1862), Haywood Tag Company Building (1928), and Jefferson High School (1927).It was listed on the National Register of Historic Places in 2001.

Saint James Lutheran Church and School located in Lafayette, Indiana was founded in 1850 by German immigrants, is a member of the Lutheran Church–Missouri Synod and is a Confessional Lutheran congregation with approximately 800 active members. Average weekly worship attendance is approximately 550 at four services. The school associated with the church was also founded in 1850, and is the oldest school in Tippecanoe County. The school serves children from age 2 through grade 8. Current enrollment is approximately 225. Saint James Lutheran School is accredited by the state of Indiana, and National Lutheran School Accreditation.

The Pottlitzer House at 801 Brown St. is in the historic Centennial Neighborhood in Lafayette, Indiana. This Pottlitzer house was constructed in 1893 by Leo and Minnie Pottlitzer. It is a mixture of Colonial Revival, Chateau and Queen Anne styles. When constructed it cost $9000, about $260,000 in today's value. The finials and oversized gables with low relief sculptures are indicative of the eclectic style popular in the late 19th century. The most notable feature, the tall spires on the roof, are the only known extant residential example of this style in Lafayette. The Pottlitzer House caught on fire in early 2015, severely damaging the rear of the structure.

James H. Ward House is a historic home located at Lafayette, Tippecanoe County, Indiana. It was built about 1875, and is a two-story Italianate / Second Empire style brick dwelling, with a 3+1⁄2-story mansard roofed tower. It features deep overhanging eaves with corner brackets, asymmetrical massing, and an ornate semi-hexagonal, two-story projecting bay. Also on the property is a contributing carriage house.: 2 It was listed on the National Register of Historic Places in 1988.

Enterprise Hotel, also known as Gasthaus Alt Heidelberg, is a historic hotel building located at Lafayette, Tippecanoe County, Indiana. It was built in 1895, and is a three-story, five-bay, rectangular, Italianate style brick building, with rear additions. It measures 42 feet wide and 32 feet deep. It is historically significant as a European style tavern / inn.: 2–3 It was listed on the National Register of Historic Places in 1984.

The Diocese of Lafayette in Indiana (Latin: Dioecesis Lafayettensis in Indiana) is a Latin Church ecclesiastical territory, or diocese, of the Catholic Church in central Indiana in the United States. The current bishop is Timothy L. Doherty. The Diocese of Lafayette in Indiana is a suffragan diocese in the ecclesiastical province of the metropolitan Archdiocese of Indianapolis.

The Cathedral of Saint Mary of the Immaculate Conception is the cathedral of the Roman Catholic Diocese of Lafayette in Indiana. It is located at 1207 Columbia Street in Lafayette, Indiana. It is also a contributing property in the St. Mary Historic District.

St. Mary Historic District is a national historic district located at Lafayette, Tippecanoe County, Indiana. In 1864, St. Mary's Catholic Church relocated from its original site at Fifth and Brown Streets to Columbia Street. With the move, many of the congregation also moved to this area. The Church became both a religious and social center for the neighborhood. Many of the homes date from the 1860s and 1870s and include fine examples of the Italianate, Greek Revival and Queen Anne styles as well as vernacular house types. Most of the people who built in this area were Lafayette businessmen. At 1202 Columbia Street James Ball, a local wholesale grocer left his name stamped into the front steps. Across the street is the James H. Ward House, who along with his brother, William, owned a local carpet and wallpaper business.James Murdock House moved onto Columbia Street in approximately 1891 after he left Michigan City, where he had been the warden of the state prison He was the operator of a grocery and produce business and in bridge and road construction. The home was sold to Ferdinand Dryfus who, with his brother Leopold, ran the Dryfus Packing and Provision Company.All structures are historically ‘Notable’ or ‘Outstanding’ examples within the Historic District. An ‘O’ rating signifies that the structure had enough historic or architectural significance to be considered for individual listing in the National Register of Historic Places. The ‘N’ rating signifies that the structure is above average and may, with further investigation be eligible for an individual listing. The contributing structures meet the basic inventory qualifications, but fails to meet individual merit, but in combination with other closely placed similar structures warrants inclusion in an historic district.

William Potter House, also known as the Potter House, is a historic home located at Lafayette, Tippecanoe County, Indiana. It was built in 1855, and is a two-story, Greek Revival style brick dwelling, with a front gable roof. A rear addition was added about 1880. The entrance features Doric order columns and opposing pilasters.: 2 It was listed on the National Register of Historic Places in 1983.