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Dr. Henry Skelton House is a historic house at 889 South Main Street in Southington, Connecticut. Built about 1748, it is a well-preserved example of colonial Georgian architecture. It was listed on the National Register of Historic Places in 1989.

The Hurwood Company is a historic industrial complex at 379 Summer Street in Southington, Connecticut. Built beginning sometime before 1884, this complex of mainly brick buildings is typical of the town's industrial landscape of the late 19th and early 20th centuries, and was where solid-headed screwdrivers were first manufactured. The complex was listed on the National Register of Historic Places in 1988.

The Pultz & Walkley Company, also known more recently as The Five Star Company, is a historic industrial complex at 120 West Main Street in the Plantsville village of Southington, Connecticut. Founded in the 1870s, Pultz & Walkley was a major producer of paper bags. The multi-building complex is one of the town's better-preserved industrial properties, and was listed on the National Register of Historic Places in 1988.

The Blakeslee Forging Company is a historic industrial complex at 100 West Main Street in the Plantsville area of Southington, Connecticut. The surviving six buildings, dating to about 1910 or later, were developed for a company founded in 1877 that specialized in drop forging. The buildings are well preserved structures typifying industrial buildings found in Southington from that era. The complex was listed on the National Register of Historic Places in 1988.

Plantsville is a neighborhood in the town of Southington, Hartford County, Connecticut. It is centered at the merger between South Main Street (road from the Milldale section) and West Main Street (road from the Marion section). As of the 2000 Census there were 10,387 people living in the Zip Code Tabulation Area for zip code 06479, which is assigned the postal city name Plantsville. The Zip Code Tabulation Area includes the entire southwestern corner of the town of Southington, including Marion and Milldale. Beginning in 2015 Plantsville (not including Marion and Milldale) was listed as a census-designated place.

The Meriden Avenue–Oakland Road Historic District is a National Register of Historic Places district covering a residential section of Southington, Connecticut, located south of the center of town. At the time of the listing, in 1988, there were 113 buildings within the boundaries of the district, of which all but 22 are considered contributing. The period of significance for the district is 1860–1936. A residence built after 1936, or altered substantially qualifies as building as non-contributing. Only one building is deemed non-contributing due to extensive modelling.

Immaculate Conception Parish - designated for Polish immigrants in Southington, Connecticut, United States. Founded on September 19, 1915. It is one of the Polish-American Roman Catholic parishes in New England in the Archdiocese of Hartford.

The Southington Public Library is the public library serving Southington, Connecticut. It is located at 255 Main Street in a modern facility erected in 1974. Its first building, constructed in 1902 and located at 239 Main Street, now houses the Southington Historical Center. That building, a fine local example of Classical Revival architecture, was listed on the National Register of Historic Places in 1989.

The Dr. J. Porter House is a historic house at 391 Belleview Avenue in Southington, Connecticut. Estimated to have been built about 1728, it is one of the town's few surviving 18th-century houses. It was home from 1754 home to one of the town's largest landowners. It was listed on the National Register of Historic Places in 1989.

The Atwater Manufacturing Company is a historic industrial property at 335 Atwater Street in Southington, Connecticut. The company, founded in 1867 and now known as Rex Forge, has long been one of Southington's major industrial employers. The ten extant buildings of the complex date as far back as 1912, and are an important element of the town's industrial past. The property was listed on the National Register of Historic Places in 1988.

The H. D. Smith Company Building (also known as the American Standard Company Building) is a historic industrial building at 24 West Street in Plantsville, Connecticut. With a construction history dating to 1882, it is one of the more architecturally interesting examples of Southington's industrial architecture, and was home to H. D. Smith & Co. from construction to the 1920s. It was listed on the National Register of Historic Places in 1977.

The Clark Brothers Factory No. 1 was a historic industrial complex at 1331 South Main Street in the Milldale area of Southington, Connecticut. Developed beginning in the 1850s, it was one of the nation's largest sources of carriage bolts. The complex listed on the National Register of Historic Places in 1988 consisted of a group of brick buildings dating to 1893 and later. It has since been entirely demolished, and the land stands vacant and overgrown.