The Kentucky Center

The Kenyon Building was the first skyscraper in Louisville, Kentucky, standing six stories tall. It was located on Fifth Street, between Main and Market Streets. The building was razed in 1974 and would eventually become the site of the Humana Building. It was designed in the Chicago school style with Richardsonian Romanesque elements, and opened in 1886. The architect was Mason Maury.

The Humana Building, also known as the Humana Tower, is a 1985 skyscraper in downtown Louisville, Kentucky, located at 500 West Main Street and headquarters of the Humana Corporation. It was built by The Auchter Company.

Riverfront Plaza/Belvedere is a public area on the Ohio River in Downtown Louisville, Kentucky. Although proposed as early as 1930, the project did not get off the ground until $13.5 million in funding was secured in 1969 to revitalize the downtown area (through which Interstate 64 had just been built). On April 27, 1973, the Riverfront Plaza/Belvedere was dedicated. Running between Third and Sixth streets, it consisted of a large parking garage and the interstate, and a grassy 7-acre (28,000 m2) park built atop. The grassy park section on the western end was the Belvedere, and the Riverfront Plaza to the east included other attractions: fountains, shelters and an ice-skating rink, as well as buildings such as the Galt House, One Riverfront Plaza and the American Life Building. The Galt House, as well as The Kentucky Center for the Performing Arts, are incorporated into the plaza with walkway access. It includes a glass elevator with access to three levels of the structure. After several lawsuits alleging that corrosive materials had damaged cars in the parking garage, a $3.8 million renovation began in 1996. The above-ground portions were renovated in 1998 to provide a wider walkway to Fifth Street, as well as less visible concrete and a concert stage. The Belvedere is adjacent to Louisville Waterfront Park, which opened in the late 1990s, with stairs and an elevator leading down to the wharf between the two. The plaza is the east terminus of the Louisville Riverwalk.

PNC Tower is a skyscraper in Downtown Louisville, Kentucky, and located at 101 South Fifth Street. It was completed in 1972 and was originally named First National Tower.

The Muhammad Ali Center is a non-profit museum and cultural center dedicated to boxer Muhammad Ali in Louisville, Kentucky. Ali, a native of Louisville, and his wife Lonnie Ali founded the museum in 2005.The six-story, 96,750 sq ft (8,988 m2) museum is located in the city's West Main District. It opened on November 19, 2005, at a cost of $80 million. It also includes a 40,000 sq ft (3,700 m2) two-level amphitheater and a plaza. On April 4, 2013, a new pedestrian bridge opened, helping residents and visitors connect from the Muhammad Ali Center's plaza to the Belvedere, the Waterfront, and other downtown attractions. The 170-foot-long walkway is nine feet wide, with exterior metal panels that complement the Ali Center plaza's design.

The German Bank Building, known also as Louisville Home Federal Building, is a historic building in Downtown Louisville, Kentucky, United States. It is located on the corner of Fifth and Market streets. The two-story structure was built in 1914 in a Beaux-Arts style with a limestone facade. In 1918, the name of the building was changed to Louisville National Bank. This was during World War I when many institutions changed names to avoid association with Germany.The building was listed on the National Register of Historic Places in 1984, for its architecture.

The Columbia Building, originally named the Commerce Building, was Louisville, Kentucky's second skyscraper, designed by Cornelius Curtin and completed in 1890 at a cost of $1 million. It was located at the northwest corner of Fourth and Main streets and built of pressed red brick in the Romanesque Revival style. It was built just five years after the world's first skyscraper, the Home Insurance Building in Chicago. It had 10 stories and a height of 162 feet.The Columbia was first called the Commercial Club Building, and was the tallest building in Louisville for over a decade. It was demolished in 1966 as a part of a downtown redevelopment plan, and a 24-story highrise, now called the BB&T Building, was built on the site in 1972.

The Galt House Hotel is a 25-story, 1,300-room hotel in Louisville, Kentucky, established in 1972. It is named for a nearby historic hotel erected in 1835 and demolished in 1921. The Galt House is the city's only hotel on the Ohio River.

The Jefferson County Courthouse Annex in Louisville, Kentucky was designed by Kenneth McDonald Sr. and built in 1900. It was listed on the National Register of Historic Places in 1980.It is a four-story steel construction building with a brick veneer, joined to the Greek Revival Jefferson County Courthouse building by a bridge on the 2nd, 3rd, and 4th floors, over a narrow street.It was designed by architect Kenneth McDonald Sr. It was described in its NRHP nomination as "stylistically a handsome complement" to the Jefferson County Courthouse.The Jefferson County Courthouse was previously listed, in 1972.

Central Station was a major train station in Louisville, Kentucky. Built in the Richardsonian Romanesque style, it served several railroad companies until the mid-20th century. It was situated at North 7th Street and West River Road, near the Ohio River waterfront, and it was also known as the 7th Street Depot. By 1969, only the Chesapeake and Ohio Railway's George Washington remained at the station. That train last called at the station in April 1971. Central Station was demolished in 1972 to make way for Interstate 64.The other major station in Louisville was Union Station. There, passenger trains of the Chicago, Indianapolis and Louisville Railroad (Monon), Louisville and Nashville Railroad and Pennsylvania Railroad were served.

Fort Nelson, built in 1781 by troops under George Rogers Clark including Captain Richard Chenoweth, was the second on-shore fort on the Ohio River in the area of what is now downtown Louisville, Kentucky. Fort-on-Shore, the downriver and first on-shore fort, had proved to be insufficient barely three years after it was established. In response to continuing attacks from Native Americans and the threat of British attacks during the Revolutionary War, Fort Nelson was constructed between what is currently Main Street and the river, with its main gate near Seventh Street. It was named after Thomas Nelson Jr., then the governor of Virginia. (Kentucky was part of Virginia at the time.) The fort was used as a courthouse and jail until one was built. The fort was garrisoned until the building of Fort Finney across the river at the site of what is today Jeffersonville, Indiana about 1784. In the fort's place today stands Fort Nelson Park, a pocket park housing a granite monument commemorating the fort.

The Louisville Metro Hall is the center of Louisville, Kentucky's government. It currently houses the Mayor's Office and the Jefferson County Clerk's Office for marriage licensing, delinquent tax filings, and the deeds room. The building was placed on the National Register of Historic Places in 1972. Construction began in 1837, and both the City of Louisville and Jefferson County governments starting using it in 1842.