Joseph Holt Ingraham House

The Nathaniel Dyer House is an historic house at 168 York Street in Portland, Maine. Built in 1803, it is one of the city's oldest surviving brick houses, rare for the building material and for its scale, which is for a middle-class family of the period. The house was listed on the National Register of Historic Places in 1987.

The William Minott House is a historic house at 45 Park Street in Portland, Maine. It is one of Portland's few Federal period houses, notably surviving the city's devastating 1866 fire. It was listed on the National Register of Historic Places on July 10, 1979.

St. Dominic's Church is an historic Catholic church building in Portland, Maine. When it was dedicated on August 11, 1833, it became the first Roman Catholic church in the city and the third in the state. Parishioners generally resided in the historically Irish neighborhoods of Gorham's Corner, Munjoy Hill (Portland) and Knightville (South Portland). Prior to the closing of the parish in 1997, it had been at one time one of the largest Irish-American Catholic parishes north of Boston. In 2003, the building was transferred to the newly formed Maine Irish Heritage Center.

Victoria Mansion, also known as the Morse-Libby House or Morse-Libby Mansion, is a historic house in downtown Portland, Maine, United States. The brownstone exterior, elaborate interior design, opulent furnishings and early technological conveniences provide a detailed portrait of lavish living in nineteenth-century America. It was declared a National Historic Landmark in 1971 for its architectural significance as a particularly well-preserved Italianate mansion.

The Park Street Row, also known as Park Street Block, is a set of historic rowhouses at 88–114 Park Street, in Portland, Maine. Built in 1835, it is the largest known 19th-century rowhouse in the state, and is a local example of Greek Revival architecture. It was added to the National Register of Historic Places in 1972.

68 High Street, formerly the Children's Hospital, is a historic colonial revival building in Portland, Maine. Located on the eastern edge of Portland's West End, the building was built in 1909 and was designed by architect Frederick A. Tompson. According to news archives, Drs. Edville Gerhardt Abbott and Harold A. Pingree and Frank W. Lamb founded this worldwide famous children's hospital for disabled children with scoliosis together in 1908. It closed in 1948, with most of the 56 patients at the time being transferred to Maine General Hospital, which was later renamed the Maine Medical Center. It also served as an annex to the Mussey Mansion until the left part of that building was demolished in 1961. It was also owned by the University of Maine system. It housed the University of Maine School of Law from 1962? until 1972, after which was used by the University of Southern Maine as administrative offices. In 2010, Community Housing of Maine sought to develop the property and the adjacent empty lot into 35 units of affordable housing. It was listed on the National Register of Historic Places March 7, 2012.The Portland Children's Hospital is known for both, its engineering and its commitment to the wellbeing of children. Edville G. Abbott, M.D., as Surgeon in Chief of the Children's Hospital, fostered the "Abbott Treatment" for adjusting bend of the spine in children experiencing scoliosis in 1911. The Abbott Treatment was viewed as the norm of care for quite some time and keeps on being referred to in clinical diaries.

The Hamblen Development Historic District encompasses a modest collection of Greek Revival residential properties at 188–208 Danforth Street in Portland, Maine. They were built in 1835–36 as a speculative venture by members of the Hamblen family, and are a rare surviving cluster of development in the city from this period. The district was listed on the National Register of Historic Places in 1992.

The Hamblen Block or Hamblen's Row is a historic series of four row houses at 188-194 Danforth Street in Portland, Maine, USA, Built in 1835, it is one of the oldest such buildings in the state, and also a rare example, as comparatively few row houses were built anywhere in the state. The row houses were added to the National Register of Historic Places in 1983, and are a contributing property to the larger Hamblen Development Historic District.

The Portland Fire Museum is a fire museum in Portland, Maine. Located at 157 Spring Street in the former home of Fire Engine 4, the museum is operated by the Portland Veteran Firemen's Association (PVFA). It showcases the history of firefighting in Portland, including a number of retired firetrucks. The PVFA was originally located at the headquarters of Casco Engine 1 which was located at 19 South Street across from what is now the Cumberland County Civic Center. The building at 19 South Street was demolished during the building of the Spring Street arterial and the PVFA moved west to the 157 Spring Street location.

The Spring Street Historic District encompasses surviving elements of the 19th-century commercial and surviving residential areas of Portland, Maine. Encompassing a portion of the city's Arts District and an eastern portion of its West End, the district has a significant concentration of residential and commercial buildings that survived the city's devastating 1866 fire. The district was listed on the National Register of Historic Places in 1970.

ZU Bakery is a bakery located at 81 Clark Street in Portland, Maine that won a James Beard award in 2024.

The McLellan-Sweat Mansion (or The McLellan House) is a historic house museum on High Street in Portland, Maine. It forms the rear component of the Portland Museum of Art complex. Built in 1800–01, the house was designated a National Historic Landmark in 1970 as a well-preserved Federal style brick townhouse.