Mark Twain Memorial Bridge

The Mark Twain Memorial Bridge was a cantilevered through truss bridge carrying US 36 over the Mississippi River. It was replaced in 2000 with the extension of I-72 and subsequently demolished.

The Mark Twain Boyhood Home & Museum is located on 206-208 Hill Street, Hannibal, Missouri, on the west bank of the Mississippi River in the United States. It was the home of Samuel Langhorne Clemens, better known as author Mark Twain, from 1844 to 1853. Clemens found the inspiration for many of his stories, including the white picket fence, while living here. It has been open to the public as a museum since 1912, and was designated a National Historic Landmark on December 29, 1962. It is located in the Mark Twain Historic District.

Mark Twain Historic District is a national historic district located at Hannibal, Marion County, Missouri. The district encompasses 20 contributing buildings in the central business district of Hannibal. It developed between about 1840 and 1936. Located in the district is the separately listed Mark Twain Boyhood Home. Other notable buildings include the Ice House Theatre (c. 1885), Randall House Antiques (c. 1845), Information Center (c. 1845), House of the Pilasters & Grant's Drug Store (1839-1844), "Becky Thatcher" House (c. 1840s), and the Mark Twain Memorial Lighthouse (1936). It was listed on the National Register of Historic Places in 1978.

North Main Street Historic District is a national historic district located at Hannibal, Marion County, Missouri. The district encompasses 27 contributing buildings in the central business district of Hannibal. It developed between about 1852 and 1935, and includes representative examples of Italianate and Beaux Arts architecture. Notable buildings include the Lone Building (1853), Brown's Drug Store (1858), Old Central Hotel (1868-1874), Old Schultz Furniture Store (c 1863), Original Farmers and Merchants Bank (1876), Jameson Hawkins Row (1852), Bernice Gano Tavern (c. 1935), and A. W. Lamb Building (c. 1870-1875).: 28–37  It was listed on the National Register of Historic Places in 1986.

Hock Building, also known as Standard Printing Company, Warehouse No. 8, is a historic commercial building located at Hannibal in Marion County, Missouri. It was built in 1872, and is a three-story brick structure, three bays wide and eight deep. It features arched windows with thick cast-iron moldings above and iron pilasters at the first floor storefront.: 42–43  It was added to the National Register of Historic Places in 1986.

Benjamin Horr House, also known as the Standard Printing Company, is a historic home located at Hannibal, Marion County, Missouri. It was built about 1855, and is a two-story, vernacular Greek Revival style brick structure. It has a front gable roof with cornice. It is the earliest surviving building to have been used for education in Hannibal, having once housed a private school run by the family of one of Mark Twain's former schoolteachers.: 40–41  It was added to the National Register of Historic Places in 1986.

Standard Printing Company, also known as the Hayward Grocery Company, is a historic commercial building located at Hannibal, Marion County, Missouri. It was built in 1879, and is a three-story, nine bay by ten bay, Italianate style brick structure. It features segmental arched windows, a lavish bracketed and modillioned cornice, and a storefront with intact cornice and iron pilasters.: 38–39  It was added to the National Register of Historic Places in 1986.

Broadway District is a national historic district located at Hannibal, Marion County, Missouri. The district encompasses 28 contributing buildings in the central business district of Hannibal. It developed between about 1866 and 1934, and includes representative examples of Italianate, Classical Revival, and Art Deco architecture. Notable buildings include the Lakenan Building (c. 1866), Kresge Building (1931), Second Farmers and Merchants Bank (c. 1910), Sproul-Cash Store (1901), Hannibal Trust Company (1909-1910), Hickman Block (c. 1865), and Robinson Brothers (c. 1894).: 18–27  It was listed on the National Register of Historic Places in 1986.

Davidson Building was a historic commercial building located at Hannibal, Marion County, Missouri. It was built between 1903 and 1905, and was a two-story Romanesque Revival style building. It had a three-bay rock-faced ashlar facade and party walls. It featured arched windows with radiating voussoirs.: 44–45  It has been demolished. It was added to the National Register of Historic Places in 1986.

Maple Avenue Historic District is a national historic district located at Hannibal, Marion County, Missouri. The district encompasses 148 contributing buildings in a predominantly residential section of Hannibal. It developed between about 1850 and 1950, and includes representative examples of Federal, Italianate, Late Victorian, Colonial Revival, and Bungalow / American Craftsman architecture. Located in the district are the separately listed Ebert-Dulany House, Rockcliffe Mansion, and Eighth and Center Streets Baptist Church. Other notable buildings include Central School by William B. Ittner, Pilgrim Congregational Church, McKnight House, Cliffside, Hogg House, the McVeigh House, the Mclntyre House, the Settles House, and the Clayton House. It was listed on the National Register of Historic Places in 2002.

Central Park Historic District is a national historic district located at Hannibal, Marion County, Missouri. The district encompasses 261 contributing buildings, 1 contributing site, and 4 contributing structures in a predominantly residential section of Hannibal. It developed between about 1840 and 1939, and includes representative examples of Romanesque Revival, Late Victorian, and Art Deco architecture. Located in the district are the separately listed Federal Building, Hannibal Old Police Station and Jail, and Eighth and Center Streets Baptist Church. Other notable contributing resources include Central Park with a war memorial monument and a life-size bronze statue of William Henry Hatch (1833-1894), City Hall (1909), old Missouri Guaranty Building (1894), Price Apartments (1904), YMCA (1910), Masonic Temple (1882), Park Methodist Church (1881, 1906), Retards Row (1855), Elks Building (1925), Holmes Building (c. 1904), Security Building (1912), Kerchival-Iakenan-Lathrop House, Admiral Coontz Birthplace, Inmaculate Conception Chapel (1854), Episcopalian Trinity Church (1860), and William C. Henn House (1937). It was listed on the National Register of Historic Places in 1982.

Mark Twain Hotel is a historic hotel building located at Hannibal, Marion County, Missouri. It was designed by Barnett, Haynes & Barnett and built in 1905. It is a four-story, Renaissance Revival style steel-frame structure with a granite foundation and beige pressed-brick exterior. The annex was built in 1918. It features semicircular arches over the main door and adjacent windows.: 50–51  It was then added to the National Register of Historic Places in 1986.