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The Humphrey Center, also known as Old Main, is an historic building located on the campus of Grand View University in Des Moines, Iowa, United States. It was listed on the National Register of Historic Places in 1978.

Grand View University is a private liberal arts university in Des Moines, Iowa. Founded in 1896 and affiliated with the Evangelical Lutheran Church in America, the university enrolls approximately 2,000 students and is accredited by the Higher Learning Commission.

The Rees Gabriel House is a historic building located in Des Moines, Iowa, United States. Gabriel was a dealer in building supplies. The basic designs for this house were drawn by C.E. Eastman and Co. and modified by Gabriel himself. The primary modifications include an extension of the turret to include an observation room in the attic, and several changes to the shape of the windows. The house is considered a good and well preserved example of the Queen Anne style. The 2½-story frame structure features an irregular plan, a hipped roof with intersecting gables and dormers, a round corner tower with a bell-shaped roof, and several porches. The house was listed on the National Register of Historic Places in 1978.

The Veneman's Bungalow Court Historic District, also known as Droukas Court, is located in Des Moines, Iowa, United States. It is the only example of a Post World War I “California bungalow court” in the city. The district has been listed on the National Register of Historic Places since 2000. It is part of The Bungalow and Square House Des Moines Residential Growth And Development, 1900-1942 MPS.

The College Corner Commercial Historic Business District, also known as the Highland Park Historic Business District at Euclid and Second, is located in the north-central section of Des Moines, Iowa, United States. It is located in the Highland Park neighborhood that also includes the Highland Park Historic Business District at Euclid and Sixth Avenues. The College Corner historic district has been listed on the National Register of Historic Places since 1998.

North High School, usually referred to simply as North, is a public secondary school located in Des Moines, Iowa. It is one of five secondary schools under the district of the Des Moines Public Schools. The school's mascot is a polar bear and the school competes in the Central Iowa Metro League conference.

The Des Moines Bus Station is an intercity bus station in the River Bend neighborhood of Des Moines, Iowa. The station, managed by Burlington Trailways, also serves Jefferson Lines. The current building was opened as a bus terminal in 2013.Des Moines has seen intercity bus transit since at least the early 1920s, when a union bus terminal operated on Sixth Avenue. In 1932, a new Union Bus Depot opened on Grand Avenue, while Burlington Bus Lines opened their own terminal in 1935 on Mulberry Street. The Burlington station was replaced in 1956 with a location on Locust Street. In 1972, a Greyhound Lines bus terminal opened on Keosauqua Way, which would be replaced by the current bus station on Second Avenue, which opened December 30, 2013.

The Riverview Park Plat Historic District is located in the north-central section of Des Moines, Iowa, United States. It has been listed on the National Register of Historic Places since 1996.

East High School, often locally referred to as East or East High, is a public secondary school located in Des Moines, Iowa, United States. East is the oldest high school in the Des Moines metro and is part of the Des Moines Public Schools. East is currently the seventh largest high school in the state by enrollment with 2,076 students.

On March 7, 2022, after 2:40 pm, a shooting occurred within the vicinity of East High School in Des Moines, Iowa, U.S, right before school was dismissed for the day. At least 35 gunshots were fired out of at least three vehicles. One 15-year-old boy was killed, and two female students were critically wounded. By the next few hours, six teenage males were arrested, ranging from ages 14 to 17, and charged with one count of first-degree murder and two counts of attempted murder: four charged in adult court, and two in juvenile court. Four more teens were eventually charged in connection to the shooting.The shooting was described by police as having gang overtones, having stemmed from an ongoing violent conflict between two rival Iowa Hispanic gangs.

The Home of Marshall's Horseradish, also known as the Marshall House, Stish House, and Marshall's Horseradish Farm, is a historic building located in Des Moines, Iowa, United States. The historic designation is made up of three resources: the two-story frame Queen Anne house, the garage, and the remains of the root cellar. They call attention to food processing for local consumption during the late 19th and early 20th-centuries. Marshall's is said to have been established as a business in 1872, and they cultivated, manufactured, and marketed horseradish condiments. The single-family house was completed in 1886. The property includes four residential lots and at one time was also the location of a small manufacturing facility (nonextant). At one time the family owned 160 acres (65 ha) around 2nd Place. While it is possible that some of that land was used to grow the horseradish, the exact location of their fields is not known for sure and the four residential lots are not large enough. The business came to an end in 1941, and the family sold the property to the city of Des Moines who built a greenhouse on the property. George Daysons, the city florist, and his wife lived in the house. The house, garage, and root cellar were listed together on the National Register of Historic Places in 1998.

The Oaklands Historic District is located in Des Moines, Iowa, United States. It was a late 19th-century residential area for upper and upper middle class residents of what was then a suburb of North Des Moines. It was also the first naturalistic suburban subdivision in the Des Moines area. The district has been listed on the National Register of Historic Places since 1996. It is part of the Towards a Greater Des Moines MPS.