West Virginia Northern Community College

Wheeling station is a U.S. historic train station located at Wheeling, Ohio County, West Virginia. It was built in 1907–1908, and is a four-story, rectangular brick and limestone building in the Beaux-Arts-style. It measures 250 feet long by 89 feet, 6 inches, deep. It features mansard roofs, built of concrete and covered with Spanish tile painted pink. Passenger service ceased in 1961. The building was remodeled in 1976 to house the West Virginia Northern Community College.It was listed on the National Register of Historic Places in 1996 as the Wheeling Baltimore and Ohio Railroad Passenger Station.

West Virginia Independence Hall is a historic government building at 1528 Market Street in downtown Wheeling, West Virginia, United States. It was built in 1860 under the supervision of architect Ammi B. Young for the federal government as a custom house, post office and courthouse. It is architecturally significant for its innovative uses of wrought iron as a framing material, and is historically significant for its role in the American Civil War. It housed the Wheeling Convention (1861), as well as the West Virginia Constitutional Convention (1863), which resulted in the separation of Unionist West Virginia from Confederate Virginia. This made it the only state to secede from a Confederate state during the war. The building was originally built as the custom house for the Western District of Virginia, and later became the center of government for the Restored Government of Virginia from 1861 to 1863, with Francis H. Pierpont serving as its governor. It was declared a National Historic Landmark in 1988. The building is now a state-run museum, housing exhibits on West Virginia history.

The Riverside Iron Works Office Building is a historic commercial building at 1507–09 Main Street in Wheeling, West Virginia. It is a four-story masonry structure, triangular in shape, and built out of light-colored brick with stone trim elements. The first three floors, built in 1896, are Richardsonian Romanesque in style, with rusticated stone elements on the ground floor at the rounded corner, and round-arch settings for doors and windows. The fourth floor, simpler in style, was added about 1907. It was built for the Riverside Iron Works, Wheeling's leading steel manufacturers at the time, and served as its headquarters until 1898, when the company was acquired by National Tube Company. In form, it is a flatiron building. The building was listed on the National Register of Historic Places for Ohio County in 2015.

Wheeling Warehouse Historic District is a national historic district located at Wheeling, Ohio County, West Virginia. The district includes 20 contributing buildings and 11 contributing structures. They are warehouses and commercial style buildings and structures between Main Street and the Ohio River. All of the buildings date to the late-19th and early-20th century. The warehouses are mostly two- and three-story masonry buildings. The two-story commercial buildings have storefronts on the first floor and residential units above. Notable buildings and structures include the Pump Store (1933), Wheeling Stamping Plant (1932), Allied Plate Glass (c. 1920), Warwick China (c. 1887), Boury Warehouse (c. 1894), Ott-Heiskell Company (c. 1871), Edward Wagner Wholesale Grocers building (1915), the Moderne style former Greyhound Bus Station, and Main Street Bridge (1891).It was listed on the National Register of Historic Places in 2002, with a boundary increase in 2022.

Ohio Valley Medical Center (OVMC) was a 200-bed health care facility in Wheeling, West Virginia. It was founded in 1890 as City Hospital. Ohio Valley General Hospital School of Nursing was established on campus in 1892, and was the first school of nursing in the state of West Virginia. OVMC was affiliated with the West Virginia School of Osteopathic Medicine, and had an osteopathic medicine residency program. The residency program offered residencies in internal medicine, emergency medicine, and traditional internal/emergency medicine fields. OVMC was also home to the OVMC School of Radiologic Technology, a two-year hospital based education program. The hospital closed permanently in September 2019.

First opening its doors in 1904, Victoria Theater is the oldest operating theater in West Virginia. Located in the registered historic market district of the city of Wheeling, the Victoria is a ~800 seat Victorian style theater with many Beaux-Arts design influences. In 1934, the Victoria Theater served, for a short period, as home to the WWVA Jamboree (later renamed "Jamboree USA"), the second-longest running radio program in the U.S.The Victoria Theater is also known as the Victoria Vaudeville Theater. It is located at Market Street between 12th and 14th streets in downtown Wheeling, West Virginia. The theater today serves as a venue for live acts, including an Elvis impersonator, country, bluegrass, rock, and gospel music. Magician Dennis Regling also performs regularly at the Victoria.

The Cathedral of Saint Joseph of Wheeling or Saint Joseph's Cathedral is the seat of the bishop of the Catholic Diocese of Wheeling-Charleston. In addition to being the seat of the bishop, the cathedral is home to the oldest congregation in the city of Wheeling, West Virginia. The cathedral is a contributing property to the East Wheeling Historic District on the National Register of Historic Places.The current pastor of the cathedral is the bishop of the Diocese of Wheeling-Charleston, the Most Reverend Mark E. Brennan. The current priest in residence is Father Justin Golna.

Robert W. Hazlett House is a historic home located at Wheeling, Ohio County, West Virginia. It was built in 1887, and is a three-story Second Empire style brick residence measuring 30 feet (9.1 m) wide and 112 feet (34 m) deep. It features a central hooded bay and a polychrome slate-covered mansard roof. The interior has many Queen Anne style details. In 1991, it housed Friends of Wheeling, Inc., a private, non-profit, historic preservation organization and four apartments.It was listed on the National Register of Historic Places in 1991.

WesBanco Arena (originally Wheeling Civic Center) is a multi-purpose arena located in Wheeling, West Virginia. It was built in 1977 at a cost of $7 million. It is home to the Wheeling Nailers ice hockey team, the West Virginia Miners indoor football team, the Mountain East Conference basketball tournament and the Ohio Valley Athletic Conference wrestling tournament.

Central Catholic High School is a parochial, Roman Catholic high school in Wheeling, West Virginia. It is part of the Roman Catholic Diocese of Wheeling-Charleston. Central Catholic High School has been educating young men and women since 1865. The school is a part of the Diocese of Wheeling-Charleston campus, which includes the Cathedral of St. Joseph, the diocesan offices, and the chancery. At the end of the 2016–2017 school year, Bishop Donahue Memorial High School closed and merged into Central Catholic.

Cathedral Parish School, also known as Wheeling Catholic Elementary and Diocese of Wheeling-Charleston Chancery, was a historic elementary school building located at Wheeling, Ohio County, West Virginia. It was built in 1896–1897, to service the St. Joseph Cathedral parish. A gymnasium addition was built in 1939. It is a three-story brick building, with an elevated first floor. It sits on a sandstone base. It features a center square tower with a pyramidal roof and Late Gothic Revival details.It was listed on the National Register of Historic Places in 1997. It is located in the East Wheeling Historic District.

The siege of Fort Henry was an attack on American militiamen during the American Revolutionary War near the Virginia outpost known as Fort Henry by a mixed band of Indians in September 1777. The fort, named for Virginia Governor Patrick Henry, was at first defended by only a small number of militia, as rumors of the Indian attack had moved faster than the Indians, and a number of militia companies had left the fort. The American settlers were successful in repulsing the Indian attack.