Greek National Road 65

Gallikos railway station (Greek: Σιδηροδρομικός Σταθμός Γαλλικός, romanized: Sidirodromikós stathmós Gallikos) is a railway station that servers the community of Gallikos, in Kilkis in East Macedonia and Thrace, Greece. The station is located just east of the settlement but still within the settlement limits. The station (as of 2021) is unstaffed, with the station buildings abandoned and left to decay.

Gallikos (Greek: Γαλλικός) is a village and a former municipality in the Kilkis regional unit, Greece. Since the 2011 local government reform it is part of the municipality Kilkis, of which it is a municipal unit. The municipal unit has an area of 149.054 km2. Population 6,343 (2011). The seat of the municipality was in the village of Kampanis. The municipality Gallikos was created after 13 small villages in the area south of the city of Kilkis merged in the late 1990s when the Greek government implemented its Kapodistrias project to fuse - and thus limit the number of - local authorities in the country.

Nea Santa (Greek: Νέα Σάντα, old name Volovot until 1926), is a small town in Kilkis regional unit, in the Central Macedonia region of Greece. It has a population of 1,693 (2011 census). The community Nea Santa (pop. 2,144 in 2011) consists of the villages Nea Santa and Panteleimon. Nea Santa is south of the city of Kilkis in the Kilkis municipality. The town was re-settled by Greek refugees from the Pontus in the 1920s, and was named after the Santa region of the Pontus (now Dumanlı). Nea Santa is close to a small industrial area providing home to few companies in the areas of textiles, plastics, processed food and industrial machinery. The 71st Airmobile Brigade "Pontos" is also located there.

Petroto (Greek: Πετρωτό, [petro'to]) is a village of the Oraiokastro municipality. The village was part of the municipality of Kallithea before the 2011 local government reform. Petroto is a part of the community of Mesaio.The 2011 census recorded 289 inhabitants in the village.

Monolofo (Greek: Μονόλοφο, [mo'nolofo]) is a village of the Oraiokastro municipality. Before the 2011 local government reform it was part of the municipality of Kallithea. The 2011 census recorded 370 inhabitants in the village. Monolofo is a part of the community of Mesaio.

Mesaio (Greek: Μεσαίο) is a village and a community of the Oraiokastro municipality. Before the 2011 local government reform it was part of the municipality of Kallithea, of which it was a municipal district. The 2011 census recorded 533 inhabitants in the village and 1,192 in the community. The community of Mesaio covers an area of 27.896 km2.

Nea Filadelfeia railway station (Greek: Σιδηροδρομικός Σταθμός Νέας Φιλαδέλφειας, romanized: Sidirodromikós stathmós Nea Filadelfeia) is a railway station that servers the community of Nea Filadelfeia, in Thessaloniki regional unit in Central Macedonia, Greece. The station is located just east of the settlement but still within the settlement limits. The station (as of 2021) is unstaffed, with the station buildings abandoned and left to decay.

Clitae or Klitai (Ancient Greek: Κλῖται) was a town of ancient Macedonia, the site of the Roman breakthrough of the Macedonian line during the Roman conquest of Macedonia. Some have identified the town as the Chaetae (Χαῖται) – "Κλ" being mistaken for "Χα" – in Ptolemy.In the Delphic Theorodochoi inscription (230 BC), published by André Plassart, there is a mention of a man who was named Phaneas Solonos (Ancient Greek: Φανέας Σόλωνος) from Clitae.Clitae is mentioned by Pliny the Elder as a centre of natron production from the ancient lake Chalastra (Ancient Greek: Χαλάστρα), which is identified as the salt lake now known as Pikrolimni. The chalestraion nitron (Ancient Greek: χαλεστραῖον [νίτρον]) produced in Clitae and used in Graeco-Roman glassmaking is mentioned by Plato in the Republic (430a) and praised for its high quality by Pliny.Combined with the identification of lake Chalastra with Pikrolimni and glassware found in the vicinity, the ruins of Clitae are considered to lie in a site near the modern village Xylokeratia of Kilkis prefecture, Greece.

Nea Filadelfeia (Greek: Νέα Φιλαδέλφεια), known before 1927 as Naresh (Greek: Νάρες), is a village and a community of the Oraiokastro municipality. Before the 2011 local government reform it was part of the municipality of Kallithea, of which it was a municipal district. The 2011 census recorded 923 inhabitants in the village. The community of Nea Filadelfeia covers an area of 12.624 km2.

Lake Pikrolimni (Greek: Πικρολίμνη 'bitter lake') is an endorheic, alkaline salt lake in Kilkis prefecture, Greece. It is located on the border of the Kilkis and Thessaloniki regional units, about 40 km northwest of Thessaloniki. The lake is hypersaline, has rather shallow waters (0.5–0.7 m) and a shoreline of about 8.5 km. The water surface area shows significant seasonal variation (3.2–4.5 km2) due to evaporation in the summer months, with an average value of 3.7 km2.Pikrolimni is the only salt lake in Greece and constitutes a biotope with rare halophytic vegetation surrounded by common reeds, which is home to various common and endangered bird species. The habitat has been listed since 1996 as a Natura 2000 site of community interest and special protection area, while also protected by the Ramsar convention.The lake was known in ancient times as Chalastra (Ancient Greek: Χαλάστρα), a famous source of natron and trona for Graeco-Roman glassmaking. In modern times it has been a site of pelo- and balneotherapy, with a spa specialising in such treatments using the lake's briny water and characteristic black mud.

Gallicum or Gallikon was a town of Crestonia in ancient Macedonia. It was situated 16 Roman miles from Thessalonica on the Roman road to Stobi.Its site is located near modern Kolchis, Kilkis, 4,5 km south of Kilkis.

Pikrolimni (Greek: Πικρολίμνη) is a former municipality in the Kilkis regional unit, Greece. Since the Kallikratis Plan for local government reform was implemented in 2011, Pikrolimni is administrated as part and constitutes a municipal unit of the municipality of Kilkis. The municipal unit has an area of 164.06 km2, and its population in the 2011 census was 5,442, down from 7,395 in 2001. The seat of the municipality was Mikrokampos. The namesake of the region, as well as its most famous attraction, is the salt lake Pikrolimni which has been historically important as a source of natron in antiquity and recognised to this day for its pelo- and balneotherapeutic properties. The current municipal unit (and former municipality) is subdivided into the following municipal departments: Mikrokampos, containing the village Mikrokampos (Μικρόκαμπος, population as of 2011: 731), earlier called Ali Hodzhalar from which chieftains of the Greek Struggle for Macedonia Ioannis Koutsokostas and Evlampios Vyziinos hailed. Anthofyto, containing the village Anthofyto (Ανθόφυτο, population as of 2011: 272), earlier name Sari Pazar, near which a prehistoric toumba and settlement named "Anthofyto A" has been discovered. Mavroneri, containing villages:Mavroneri (Μαυρονέρι, population as of 2011: 535), originally the Turkish-inhabited Kara Bunar, repopulated in 1928 by Greek refugees from Asia Minor after the population exchange as a result of the Treaty of Lausanne. Ano Apostoloi (Άνω Απόστολοι, population as of 2011: 267), earlier name just Apostoloi or Paliokklisia (15th century AD), near the ancient Macedonian town of Morrylos, home of a cult of Asclepius. Mesoi Apostoloi (Μέσοι Απόστολοι, population as of 2011: 113), founded in 1924 near Apostoloi by Greek refugees from Asia Minor and the Pontus.Neo Agioneri, containing the village Neo Agioneri (Νέο Αγιονέρι, population as of 2011: 1176), also known as Nea Varlantza/Verlatza, founded in 1926 by Cappadocian Greek refugees from Cappadocia. Neo Gynaikokastro, containing villages:Neo Gynaikokastro (Νέο Γυναικόκαστρο, population as of 2011: 578), older names Avret Hisar and Nea Dimitra, in the vicinity of the 14th century castle built by Andronikos III Palaiologos and since 1926 populated by Greek refugees from Eastern Thrace (Çatalca district) and the Caucasus. Vakoufi (Βακούφι, population as of 2011: 16), first officially listed as a settlement in 1940. Kato Apostoloi (Κάτω Απόστολοι, population as of 2011: 408), locally also called Thrakiotiko, founded in 1922 near Apostoloi by Greek refugees from Eastern Thrace (hence the local name). Kokartza (Κοκάρτζα, population as of 2011: 48), populated in 1928 by Greek refugees from Asia Minor.Palaio Agioneri, containing the village Palaio Agioneri (Παλαιό Αγιονέρι, population as of 2011: 886), earlier name just Agioneri or Verlatza, repopulated in the early 1920s by Pontic Greek refugees mainly from the Caucasus. Xylokeratia, containing villages:Xylokeratia (Ξυλοκερατιά, population as of 2011: 273), older name Hadzhilar, located near the ruins of the ancient city Clitae (centre of ancient natron production from lake Pikrolimni) and by the early 20th centruty inhabited by Bulgarians and Turks before the population exchanges in the aftermath of the Balkan and Greco-Turkish wars; afterwards repopulated by Greek refugees mostly from Eastern Rumelia (southern Bulgaria). Mpakeika (Μπακαίικα, population as of 2011: 25), near a different prehistotic settlement (location Lofos Karditsa), first officially listed as a settlement in 1961. Pikrolimni (Πικρολίμνη, population as of 2011: 25), previously known as Gyolbash, originally Bulgarian-inhabited until repopulated by Greek refugees from Asia Minor, Eastern Thrace and the Pontus as a result of population exchange.