Rochester City School No. 24

Highland Hospital is located in Rochester, New York, and is an affiliate of the University of Rochester Medical Center (URMC), which is part of the University of Rochester. Founded in 1889, the hospital is involved in specialties such as bariatric surgery, joint replacement, geriatric care, women's services and maternity. The organization has 261 beds and 2,400 employees.

Linden–South Historic District is a national historic district located in the South Wedge neighborhood of Rochester in Monroe County, New York. The district consists of 136 contributing buildings, including 82 residential buildings, 53 outbuildings, and one church. The houses were constructed between 1872 and 1913 in a variety of vernacular interpretations of popular architectural styles including Gothic Revival, Italianate, Queen Anne, and Colonial Revival styles. The houses are 2 1/2-stories, are of frame or brick construction, and were designed by local architects employed by the developer Ellwanger & Barry. Among the more prominent are Andrew Jackson Warner and Claude Bragdon. The church is the former South Avenue Baptist Church, now Holy Spirit Greek Orthodox Church, built in 1909–1910 in a Late Gothic Revival style. Also in the district is a three-story, Queen Anne style mixed use building, with commercial space on the first floor and residential units above, located at 785 South Avenue (c. 1890).The area was developed by George Ellwanger and his partner Patrick Barry after they entered the real estate business in 1856. The district is located on the oldest part of the Ellwanger & Barry nursery, which they subdivided into residential lots and developed between 1872 and 1913.It was listed on the National Register of Historic Places in 2009.

The Cinema Theater is a motion picture theater in Rochester, New York. Opened as a neighborhood motion picture theater in 1914, it is one of the oldest continuously operated motion picture theaters in the United States. The theater is located at the corner of South Clinton Avenue and South Goodman Street in Rochester.

A statue of Frederick Douglass sculpted by Sidney W. Edwards, sometimes called the Frederick Douglass Monument, was installed in Rochester, New York in 1899 after it was commissioned by the African-American activist John W. Thompson. According to Visualising Slavery: Art Across the African Diaspora, it was the first statue in the United States that memorialized a specific African-American person.Originally located by the Rochester station, the statue was moved in 1941 to Highland Bowl, a natural amphitheater in Highland Park. The statue was relocated again in October 2019, becoming the centerpiece of a new Frederick Douglass Memorial Plaza. The base is surrounded by plaques bearing words from Douglass's speeches.

South Wedge is a historic district and neighborhood in southeast Rochester, New York, in a predominantly residential section of the city. The district includes a variety of buildings constructed between the 1840s and 1920s, mainly two-story detached family residences. The architecture is primarily vernacular with a few examples of high-style Italianate and Queen Anne style residences, and the separately listed Saint Andrew's Episcopal Church and Nazareth House. Other notable buildings include St. Boniface Church, School 13, School 28, and Engine Company No. 8.It was listed on the National Register of Historic Places in 2013.

David Hagaman House is a historic home located at Rochester in Monroe County, New York. It was constructed about 1840 and is a typical example of vernacular Greek Revival style rural domestic architecture in Western New York. The main block is a 2+1⁄2-story brick structure with a gable roof.It was listed on the National Register of Historic Places in 1994.

Meigs–Goodman is a former Rochester Industrial and Rapid Transit Railway station located in Rochester, New York. It was closed in 1956 along with the rest of the line.This station was built between Meigs Street and Goodman Street South in a cutting that had once been the bed of the Erie Canal and is now a section of the Eastern Expressway.

Highland Park, also known as Highland Botanical Park, is an arboretum in Rochester, New York, United States. Its administrative office is located at 171 Reservoir Avenue in Rochester. The park is one of several in Rochester originally designed by Frederick Law Olmsted, including Genesee Valley Park, Maplewood Park, and Seneca Park, which is now a zoo.

Mt. Hope–Highland Historic District is a national historic district located at Rochester in Monroe County, New York. Its encompassed by the neighborhoods of Mount Hope and Highland Park. It has a diverse range of architectural styles. The district was the exclusive domain of the Ellwanger and Barry Botanic Gardens and Mt. Hope Cemetery throughout the mid- and late-19th century. It retains its elegant and spacious character of park land. Its features The district is punctuated with notable architect-designed buildings combined with more tightly knit early 20th century subdivision along the district's fringes. Among the notable buildings are the Warner Castle (1854), a 22-room mansion that is home to the Rochester Garden Center. The Mt. Hope Cemetery includes a little Gothic chapel designed by Andrew Jackson Warner. The cemetery is also known for its beautiful landscaping and picturesque views. It was listed on the National Register of Historic Places in 1974.

James Monroe High School is a public high school in Rochester, operated by the Rochester City School District.

Nazareth House, also known as St. Andrew's Parish House, is a historic building in Rochester, Monroe County, New York, United States. It is a three-story, brick institutional building built in 1893 and enlarged in 1911. The original section is a three-story, five-bay, red brick structure in the Neoclassical style. The building was once used for social and education services, but was renovated in the early 1980s into six apartments.It was listed on the National Register of Historic Places in 1984. It is located in the South Wedge Historic District.

School Without Walls, located in Rochester, New York, United States, is a high school for students in grades 9-12, and is an example of an alternative school.