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Moesa District, often referred to as Moesano, is a former administrative district in the canton of Graubünden, Switzerland. It had an official language of Italian, a population of 8,125 in 2015, and an area of 473.74 km2 (182.91 sq mi), corresponding to the Mesolcina valley along the eponymous Moesa River. On 1 January 2015 the former municipalities of Arvigo, Braggio, Selma and Cauco merged to form the new municipality of Calanca. The Moesa District was replaced with the Moesa Region on 1 January 2017 as part of a reorganization of the canton.

The Moesa Region is one of the eleven administrative districts in the Canton of the Grisons (or in German: Graubünden) in Switzerland. It had an area of 473.74 square kilometers (182.91 sq mi) and a population of 8,770 (as of 31 December 2020).. It was created on 1 January 2017 as part of a reorganization of the Canton. The region borders with the Viamala Region to the north, with Italy to the east (Lombardy: Province of Sondrio and of Como) and with the Canton of Ticino (districts of Bellinzona to the southwest, Riviera and Blenio) to the west.

Pala Castle (Italian: Torre di Pala) is a tower in the municipality of San Vittore of the Canton of Graubünden in Switzerland. It is a Swiss heritage site of national significance.

San Vittore is a municipality in the Moesa Region in the Swiss canton of Grisons (Graubünden).

Castaneda is a municipality in the Moesa Region in the Swiss canton of the Grisons.

Grono is a municipality in the Moesa Region in the Italian speaking part of the Swiss canton of Grisons. On 1 January 2017 the former municipalities of Leggia and Verdabbio merged into the municipality of Grono.

Leggia is a former municipality in the district of Moesa in the Swiss canton of Graubünden. On 1 January 2017, the former municipalities of Leggia and Verdabbio merged into the municipality of Grono.

Buseno is a municipality in the Moesa Region in the Swiss canton of Graubünden.

Torre Fiorenzana is a castle in the municipality of Grono of the Canton of Graubünden in Switzerland. It is a Swiss heritage site of national significance.

Santa Maria in Calanca Castle (Italian: Torre di Sta. Maria) is a tower in the municipality of Santa Maria in Calanca of the Canton of Graubünden in Switzerland. It, along with the neighboring Church of the Assumption of St. Mary, are both Swiss heritage sites of national significance.

Verdabbio is a former municipality in the district of Moesa in the Swiss canton of Graubünden. On 1 January 2017 the former municipalities of Leggia and Verdabbio merged into the municipality of Grono.

Santa Maria in Calanca is a municipality in the Moesa Region in the Swiss canton of the Grisons.