Iglesia San Agustín, Chile

The Teatro Municipal, National Opera of Chile is the most important stage theatre and opera house in Santiago, Chile.

The casa matriz del Banco de Chile is a building in downtown Santiago, Chile, which houses the headquarters of the Banco de Chile. It is located at 251 Paseo Ahumada street, between Huérfanos y Agustinas streets. The building was declared as a National Monument of Chile in 2016, within the category of Historic Monuments.

Casa Colorada (English: Red House) is a colonial house built located in Santiago, Chile. It was built in 1769, by Joseph de la Vega for Mateo de Toro y Zambrano, and currently houses the Museo de Santiago (English: Museum of Santiago). The house has a clay-tiled roof, balconied windows, and deep-red walls, and consists of two storeys.Visitors walk through the homes two large patios to get the Museo de Santiago, which occupies five of Casa Colorada's rooms. The museum explores Santiago's history from the Pre-Columbian era to contemporary times.

The Edificio Comercial Edwards is a cast-iron building used for retail, which is located at the corner of Merced and Paseo Estado streets, on the southeast side of the Plaza de Armas of Santiago. It was designed by Eugenio Joannon and prefabricated in France in 1892, for later being assembled in Chile.In 1902, Agustín Edwards Mac-Clure acquired the property to transfer it to his brother Raúl, who sold the building to Agustín Gómez. The property was awarded to the Banco Español in 1909 and sold to the Archdiocese of Santiago in 1910. In the 1930s, the building changed hands once again to the Mutual de la Armada, and in 1942 the property was purchased by Etelvino Villanueva, to lease retail space on its first floor. In 1972 the building was declared a Monumento Histórico, and in 1986 went on to form part of the Zona Típica (Heritage District) of the historic downtown of Santiago.

Miguel de Cervantes University (Spanish: Universidad Miguel de Cervantes) is a private university located in Santiago de Chile and was established on 1996. This university had around 853 students in 2010. It is accredited by Chile's National Accreditation Commission (CNA-Chile).Founded in 1996, it was officially recognized as a university on November 27, 1997, by Exempt Decree No. 1169 of the Ministry of Education. Its only campus is located at calle Mac Iver 370, Santiago commune near Metro stations Santa Lucia (Line 1), Bellas Artes and Plaza de Armas (Line 5). It is located within the historic center of the city. The university became autonomous on January 15, 2009.Miguel de Cervantes University is one of eight Chilean universities that are not accredited by the National Accreditation Commission (CNA-Chile). Moreover, it is in 56th and last place in América Economía magazine's 2012 ranking of Chilean universities. It is not mentioned in the El Mercurio 2006 ranking of universities and QS World University Rankings 2012. It is ranked 69th in Chile (15596th worldwide) in the "Webometrics Ranking of World Universities" conducted by the Cybermetrics Lab, a research group belonging to the Spain's Consejo Superior de Investigaciones CientíficasThe university currently offers seven programs leading to a master's degree and three in the areas of Commercial Engineering, Social Work and Political Science. The university has 113 faculty members.

Portal Fernández Concha is a historic mixed-use building in Santiago, Chile. Built in 1871 as a commercial building including a hotel, it forms the south side of the central Plaza de Armas. It was registered on 3 December 1986 as a national monument as part of the zona típico consisting of the square, the former National Congress building and nearby buildings.

The Iglesia de las Agustinas is a Catholic church, located in downtown Santiago, Chile. The church was declared as a National Monument in 1977.

The San Francisco Church (Spanish: Iglesia de San Francisco) is a Franciscan church on Avenida Libertador General Bernardo O'Higgins, in the downtown of Santiago de Chile. The church, along with the adjacent convent, is one of the oldest colonial-era buildings in the country. It has been resistant to about 15 earthquakes of magnitude over 7.

Edificio Ariztía is a building located at 52 Nueva York Street in downtown Santiago, Chile, on a wedge-shaped city block. It was completed in 1921 and is considered the first "skyscraper" in Santiago. The building, constructed in reinforced concrete, was the first office building in Santiago with an elevator.

Museo Colonial (English: Colonial Museum) is a historical, cultural and religious museum located in Santiago, Chile. The museum explores the colonial period of Chile and South America, with a collection of paintings, sculpture, furniture and other objects. Many of the pieces are religious, and were created in Peru, the former colonial capital. The museum also features a genealogical tree of the Franciscan Order which is "gigantic" in size and includes 644 miniature portraits.The museum is housed in the convent adjacent to San Francisco Church.

The Edificio Ex Hotel Mundial is a former hotel building in Santiago, Chile. Located on a triangular lot, the building was commissioned by La Mundial Insurance Company and built in 1920–1923. In 1935, the building was offered for rental and operated as a hotel until 1975.It is close to the Iglesia de las Agustinas. The building shares a similar architectural style with the building housing the Santiago Stock Exchange and the Club de la Unión, all of which are located in the same area as the Edificio Ariztía, which is bordered by the Paseo Ahumada to the east and the Alameda Avenue to the south. The main corner of the building features a cylindrical structure, which is adorned with pilasters and topped with a cupola.

Universidad de Chile (in Spanish: University of Chile) station is a transfer station between the Line 1 and Line 3 of the Santiago Metro. It is an underground station located between La Moneda and Santa Lucía stations on the same line. It is located at the junction of Avenida Libertador General Bernardo O'Higgins, also known as "Alameda", and Paseo Ahumada in the commune of Santiago. The Line 1 station was opened on 31 March 1977 as part of the extension of the line from La Moneda to Salvador. The Line 3 station was opened on 22 January 2019 as part of the inaugural section of the line, from Los Libertadores to Fernando Castillo Velasco.