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Meade County High School (formerly Brandenburg High School) is a public high school in Brandenburg, Kentucky, United States. It was established in 1914, and is part of the Meade County Schools district. It serves the county, except for people living on Fort Knox; people living on Fort Knox are instead zoned to the Department of Defense Education Activity (DoDEA), which operates Fort Knox Middle High School.

Brandenburg United Methodist Church (formerly Brandenburg United Methodist Episcopal Church) is a historic church at 215 Broadway in Brandenburg, Kentucky. It was built in 1855 and added to the National Register of Historic Places in 1984.The church received a rear addition in 1893.

Brandenburg is a home rule-class city on the Ohio River in Meade County, Kentucky, in the United States. The city is 40 miles (64 km) southwest of Louisville. It is the seat of its county. The population was 2,894 at the 2020 census.

The Edward Yeakel House, at 116 Decatur St. in Brandenburg, Kentucky, was built around 1885 to 1890. It was listed on the National Register of Historic Places in 1984.It is Queen Anne in style. It is two-and-a-half-stories tall, and has a three-story tower. It was built for Edward Yeakel, a merchant in Brandenburg. It was bought in 1920 by a Dr. Baxter, who used it for a medical office and as a residence. The property was deemed "architecturally significant as the outstanding example of the Queen Anne style in Brandenburg."The listing included a second contributing building, which might be either a one-story root cellar built of limestone and brick, or a one-story frame carriage house.

The Jones-Willis House, at 321 Main St. in Brandenburg, Kentucky, was built around 1920. It was listed on the National Register of Historic Places in 1984.It is a concrete block house built by and for the Jones family who operated a concrete plant located next to the house. It was deemed "architecturally significant as the best representation of a concrete dwelling in Brandenburg. The dwelling exhibits qualities of excellent workmanship and design."

The Brandenburg Commercial District, on Main St. in Brandenburg, Kentucky, is a 3.5 acres (1.4 ha) historic district which was listed on the National Register of Historic Places in 1986. It included seven contributing buildings.It includes: Ace Theatre Dr. Blair Building Brandenburg Moose Lodge (formerly Applegate Ford Motor Company) F. W. Casperke Building Farmers' Deposit Bank Building Hotel Meade Meade County Messenger Building

The Meade County Jail, in Brandenburg, Kentucky, was built in 1906. It was listed on the National Register of Historic Places in 1984.It is a two-story common bond brick building with a two-story brick ell. It overlooks the Ohio River.It was the third jail of Meade County. The first was a log building built in 1826. The second was an 1854 brick building. Bricks from the second jail building were used in the construction of this 1906 building.Now known as Jailhouse Pizza, the building was featured in an episode of Ghost Hunters in 2016 and an episode of The Paranormal Journey in 2017.

Doe Run Inn is a restaurant/inn business two miles southeast of Brandenburg, Kentucky. It is within the Doe Run Creek Historic District, which was placed on the National Register of Historic Places on December 19, 1978. Squire Boone had discovered the creek, along with John McKinney, in 1778, and named it Doe Run Creek. It was so named due to the many deer in the vicinity. The creek had sulfur and salt licks, making it attractive for buffalo and elk. The mill was built between 1788 and 1790 by Jonathan Essery, and was originally known as Stevenson's Mill. It was made of local limestone and timbers that were hand-hewn. The walls are two feet thick. Thomas Lincoln worked as a stonemason on the newer section of the mill, which was constructed in 1800.Throughout its history as a mill, it was seldom profitable, due to so many competing mills. By 1900 it was being used as a barn. It became the Sulfur Wells Hotel in 1901 when W.D. Coleman purchased it. It attracted several tourists who sought the purported health benefits of the sulfur water. In 1947 the Haycrafts leased the Inn. It was renamed the Doe Run Inn in 1958 when it was leased by Curtis and Lucille Brown. The district includes an additional mill and three houses, one of which was a log cabin. Also within the district was Meade County's first hydro-electric plant.

Doe Valley is an unincorporated community and census-designated place (CDP) in Meade County, Kentucky, United States. Its population was 2,270 as of the 2020 census.Doe Valley was originally conceived as a planned residential community in 1965.

Matthew E. Welsh Bridge is a two-lane, single-pier cantilever bridge on the Ohio River. The bridge connects Kentucky Route 313 and Indiana State Road 135, as well as the communities of Brandenburg, Kentucky and Mauckport, Indiana. It is 3,098 ft (944 m) long and was built at a cost of 5.5 million dollars, financed mainly by the State of Indiana. The truss portion of the bridge is continuous across two 725 ft (221 m) spans. Construction of the bridge began in August 1964 and the bridge was opened to traffic on November 19, 1966. The bridge was named after Matthew E. Welsh, the 41st governor of Indiana. Although 90% of the bridge is within the Commonwealth of Kentucky, it is owned and maintained by the State of Indiana.

Mauckport is a town in Heth Township, Harrison County, Indiana, along the Ohio River. The population was 81 at the 2010 census.