Blackstone River and Canal Heritage State Park

Rogersons Village Historic District is a historic mill village in Uxbridge, Massachusetts, United States.

The R. Farnum House is an historic house located at 22 Oak Street, in Uxbridge, Massachusetts. This 2+1⁄2 story wood-frame house was built c. 1875–80, and is a well-preserved local example of Gothic Revival styling. It has an elaborately decorated front porch, and bargeboard decoration and a pierced apron in the main gable end. The gable details are repeated in gable ends on the north side of the house. Nothing is known about R. Farnum, who was probably from the locally numerous Farnums who settled the area in the 18th century.On October 7, 1983, it was added to the National Register of Historic Places.

The North Uxbridge School, also known as the Virginia A. Blanchard School, is an historic school building at 87 East Hartford Avenue in Uxbridge, Massachusetts. Built in 1873 and enlarged in 1900, it served as a public school until 2002. It was listed on the National Register of Historic Places in 1983 for its architectural and community significance. It is slated in 2015 to be converted into affordable housing.

The Richard Sayles House is an historic house at 80 Mendon Street, in Uxbridge, Massachusetts. It is a distinctive local example of Federal period architecture executed in granite. It is further notable has the home from about 1859 onward of Richard Sayles, a local mill worker, executive, and later owner. It was added to the National Register of Historic Places on October 7, 1983.

Wheelockville is a village in the town (township) of Uxbridge, Massachusetts, United States. Part of the village centering on Mendon and Henry streets is listed on the National Register of Historic Places as the Wheelockville Historic District. Wheelockville appears on the Blackstone U.S. Geological Survey Map. The Village receives municipal services from Uxbridge, for fire, police, EMS, School district, public works, and other services. Worcester's Judicial District includes Uxbridge District Court. The geography of Wheelockville includes several other distinct mill villages, including: Hecla and Elmdale.

The Israel Southwick House is an historic house located at 76 Mendon Street (at its northwest corner with Oak Street), in Uxbridge, Massachusetts. The 2+1⁄2 story wood-frame house was built c. 1860–65, and is a good local example of Italianate styling, with Queen Anne elements added c. 1890. The main facade is three bays, with a center entry that has an elaborate colonnaded porch with a gable front roof. Above the entry is a Palladian window with a small half-round window surmounting the central of three relatively narrow windows. There is a gable-roof dormer with three windows above. To the left of the entry is a single story porch that has been enclosed, and a rounded corner porch extends to the right of the entry.On October 7, 1983, it was added to the National Register of Historic Places, where it is listed at 70 Mendon Street.

The Wheelockville District is an historic district located at Mendon and Henry streets in the village of Wheelockville in Uxbridge, Massachusetts. It encompasses a collection of modest Federal and Greek Revival period worker housing, built primarily to house families of workers at the nearby Waucantuck Mill Complex. The oldest houses in the area were built c. 1825–35, and include cottages built by the mill owners. A second phase of growth between about 1860 and 1885 resulted in the construction of a number of buildings with vernacular Victorian elements, as well as the somewhat more ornate Italianate Wheelock House at 173 Mendon Street, which was built for a manager at another Uxbridge mill. The district runs roughly along Mendon Street (Massachusetts Route 16) from Hecla Street to the junction of Mendon and Henry Streets, and then along those two streets for about six houses.The district was listed on the National Register of Historic Places in 1984.

The Charles Capron House is an historic house at 2 Capron Street in Uxbridge, Massachusetts. Built in 1874, it is an locally distinguished example of Gothic Revival architecture. It is also notable for its association with Charles Capron, a local mill owner. The house was listed on the National Register of Historic Places in 1983.

The Cornet John Farnum Jr. House, built circa 1710, is one of the oldest homes in the historic Blackstone Valley town of Uxbridge, Massachusetts. On May 7, 1980, it was added to the National Register of Historic Places.

The Benjamin Adams House is a historic house located at 85 North Main Street, in Uxbridge, Massachusetts. Probably built before 1792, it is a good quality example of Federal period architecture, built for a prominent local lawyer and businessman. On October 7, 1983, it was listed on the National Register of Historic Places.

The William Hayward House is an historic house located at 77 North Main Street, in Uxbridge, Massachusetts. This 2+1⁄2 story wood-frame house was built in 1876 for William Hayward, a banker and business partner of the locally prominent mill owner Moses Taft. The house is an excellent local example of Italianate styling, although its elaborate porch is a later c. 1900 modification. The property also has a period carriage house in good condition and has been occupied by the George and Louise Kurzon family for 100 years.On October 7, 1983, it was added to the National Register of Historic Places.

The Uxbridge Free Public Library is the public library in Uxbridge, Massachusetts. It opened in 1875. The first library in the town of Uxbridge was the Uxbridge Social and Instructive Library (1775–1812), managed by George Southwick at his store in the Quaker City section of South Uxbridge. The sixth was the Uxbridge Agricultural Society (1859–1864). Most of these small libraries were subscription libraries that required dues and assessments. In 1874, the Uxbridge voters elected six trustees to set up a free library. They met on April 18, 1874 to organize the Uxbridge Free Public Library. It opened in the FW Barnes jewellery store on South Main Street on January 20, 1875. After five years, the free library moved into the Town Hall. On June 20, 1894. the library's new home, the Thayer Memorial building, was dedicated . Edward Carrington Thayer, a local business man and banker, had built it and donated it to the town in memory of his parents, Joseph and Chloe Taft Thayer The Thayer Memorial building was designed by Fuller & Delano of Worcester as architects and the building contract to Urgel Jacques of Worcester. Thayer spent $28,000 for the building, $4,000 for the land and $1,500 for furnishings, for a total of $33,500. The Thayer Memorial building still houses the Uxbridge Free Public Library.