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The Dayton Daily News Building is a historic structure located at the corner of 4th and Ludlow Streets in Dayton, Ohio. It was designed by architect Albert Pretzinger for Dayton Daily News founder James M. Cox. According to Cox's autobiography, he was turned down for a loan by a local banker who told him “Newspapers have never been known to earn money. Of course we can’t accommodate you.” After being turned down for a bank loan to start the paper, Cox asked Pretzinger to "build him a damn bank" so it was modeled after the Knickerbocker Trust building in New York City. Among the most significant components of the three-story building are those surrounding the entrance: three bays wide, the facade features a set of Corinthian columns, a set of fluted columns in the Doric order that form a grand frontispiece around the entrance, and a partial pediment with a cornice supported by cornucopiae. Its walls are built of a mixture of wood and granite.The building was erected between 1908 and 1910 and expanded in the 1920s, 1950s and 1970s. The 1908 building was remodeled in 1989. On November 30, 1978, it was added to the National Register of Historic Places. In April 2007, the newspaper's editorial and business offices moved to the former NCR Building 31 at 1611 S. Main St. on Dayton's south side, near the University of Dayton campus. The newer portions of the Dayton Daily News building were demolished in 2013. Only the 1908 building on the corner remains. The Schwind Building at 27 Ludlow, built in 1913, was imploded on August 17, 2013, as part of the demolition process.

The Commercial Building is a historic skyscraper in central Dayton, Ohio, United States. Constructed in the early twentieth century, it played an important part in the development of the western portion of downtown Dayton, and it is one of the most prominent surviving examples of the work of one of the most significant architects in the city's history. Located at the edge of what was once one of the city's leading commercial complexes, it has been named a historic site.

40 West 4th Centre is a 331 ft, 22-story office skyscraper located in Dayton, Ohio. Upon its completion in 1969, it was the tallest building in Dayton, but was surpassed by the Kettering Tower one year later. It is now the fourth tallest building. It was designed by architect Paul H. Deneau.

The Dayton Arcade is a collection of nine buildings in Dayton, Ohio. The Arcade is a historic, architecturally elegant complex in the heart of Dayton's central business district. Built between 1902 and 1904, it was conceived by Eugene J. Barney of the Barney & Smith Car Company and consists of nine interconnecting buildings topped by a glass-domed rotunda, 70 feet (21 m) high and 90 feet (27 m) in diameter (detailing around the dome includes oak leaves and acorns, grain, rams' heads, wild turkeys, and cornucopia), below which two balconied upper floors circle the central enclave. As president of the Arcade Company, Barney made sure the Arcade had the latest innovations, including elevators, a power plant and a cold-storage plant. The architect was Frank M. Andrews, known also as architect for many of NCR's factory buildings (notable for their use of progressive fenestration) and the American Building (originally Conover) at Third and Main Streets in Dayton.

The Benjamin F. Kuhns Building is a historic commercial building on Main Street in downtown Dayton, Ohio, United States. Distinguished by its little-modified late nineteenth-century architecture, it has been named a historic site. Built of brick covered with a slate roof, the Romanesque Revival building features elements of stone and terracotta. Its facade is divided into five bays, each of which features a large arch, while the street-facing southern side is functionally a larger form of the facade. The building was designed by Peters and Burns, a Dayton-based architectural company, and constructed under the direction of Dayton contractors Beaver and Butt. During the building's early years, it was home to companies such as the Manhattan Clothing Store and Oleman's Department Store, which maintained premises there in the 1890s and 1910s respectively. However, the building was not always used for commercial purposes; an arts school operated in the building during the 1888-1889 schoolyear. Among the building's interior features is a mail chute, which according to local lore is one of the earliest installed in any building nationwide.Benjamin Kuhns, the building's namesake, moved from Lancaster, Pennsylvania to Dayton in 1855 at the age of thirty. By his fiftieth birthday, Kuhns was a prominent industrialist, having taken a small Dayton firm and turned it into a prominent manufacturer of agricultural equipment. He was also a prominent philanthropist, having been one of the primary founders of Miami Valley Hospital.The Benjamin Kuhns Building was listed on the National Register of Historic Places in April 1978, qualifying because of its historically significant architecture. By the early twenty-first century, the Kuhns Building had undergone a highly successful redevelopment process, but like the Kettering Tower and several other downtown buildings, it experienced foreclosure in 2010 after the corporation that owned it fell behind on the mortgage and on property taxes. In 2019, it was sold by the city of Dayton to a developer.

The Lindsey Building is a historic commercial building in the downtown section of the city of Dayton, Ohio, United States. Built in the early twentieth century, the Lindsey has been named a historic site. Constructed of brick on a stone foundation, the Lindsey Building's architecture is typical of commercial buildings erected in the early twentieth century. Some of its more distinctive components are Neoclassical, including its three-part facade and some of its smaller details. Twelve stories tall, the building has been modified to include room for modern-styled shops on its first two floors; the main entrance is located in a recessed area to the right (from the perspective of someone inside the building) of the shop space. It was renovated to new apartments as part of the city block revitialation of the Dayton Arcade. Built for Theodore Lindsey, the Lindsey Building was constructed in 1917 at a time when Dayton was highly prosperous. During the late 1910s, the downtown was experiencing sustained growth, and numerous commercial buildings such as the Lindsey were being constructed. For much of its history, it has housed financial institutions, including the Miami Savings and Loan Company and the Mutual Home and Savings Association.In 1985, the Lindsey Building was listed on the National Register of Historic Places; by the early 2010s, it was one of approximately one hundred such locations in the city of Dayton. It qualified for designation in two separate ways: because of its architecture, and because of its place in local history, for it was deemed a leading example of the downtown's expansion in the early twentieth century.

Fifth Third Center is a high-rise office tower located in Downtown Dayton, Ohio.

Sacred Heart Catholic Church is a historic Catholic church building in downtown Dayton, Ohio, United States. Constructed at the end of the nineteenth century for a new parish, it closed in 1996, but was reopened in 2001 when a Vietnamese Catholic group began to use the church. This church building remains significant because of its grand architectural elements, which have led to its designation as a historic site.

The Graphic Arts Building is a historic commercial building on the edge of downtown Dayton, Ohio, United States. Built in the 1920s, it long housed the publishing house of a Protestant denomination, and it has been named a historic site.

The Edwin Smith House is an historic structure in Dayton, Ohio. It was added to the National Register of Historic Places on August 13, 1974. It is also known as the Dayton Bicycle Club and Craighead House.

The International Peace Museum (formerly the Dayton International Peace Museum) is a non-profit, peace museum located on historic Courthouse Square in downtown Dayton, Ohio, United States. The museum's mission is to promote, through education and collaboration, a more equitable, civil, and peaceful world. Its programs and exhibits are non-partisan, secular, and feature themes of conflict resolution, equity, social justice, tolerance, and protecting our natural world. It commemorates the 1995 Dayton Agreement that ended the war in Bosnia. It is "America's only brick-and-mortar peace museum." In addition to functioning as a traditional museum, the Peace Museum serves as an activities center for those who seek a community of peace. The Museum features permanent, temporary, and traveling exhibits that highlight the rich history of, and potential for, nonviolent solutions to conflict and sustainability in the natural world. The Museum hosts two to three guest exhibits annually. Located in the Courthouse Plaza Building on Dayton's Courthouse Square, the Peace Museum includes a library, an interactive children's room, a studio, the Jack Meagher Gallery, traveling and permanent collections, a stage, and small gift shop. The Museum holds events such as book discussions and live music, storytelling, and guest speakers.The museum is open from 10 A.M to 5 P.M Friday and Saturday for visitors and Tuesday -Thursday for scheduled school visits and group tours. The admission is $5, and it is free for members.

The Centre City Building (formerly known as the United Brethren Building) is an historic building at 36-44 South Main Street at the corner of East Fourth Street in downtown Dayton, Ohio. It was designed by Charles Herby and built in 1904 by the F.A. Requarth Co. for the sum of $305,000 as the headquarters of the Church of the United Brethren in Christ Christian denomination. Originally 14 stories, it was the tallest building in Dayton from 1904 until 1931. A seven-story tower portion was completed in 1924, capped by a chapel for the Church, making it 21 stories total. It is considered to have been Dayton's first skyscraper.It housed the general offices of the church, and of the succeeding Evangelical United Brethren Church. It also served as headquarters to the United Brethren Publishing House.It was sold in 1975, converted to a personal residence by its owner, then sat vacant by 2012.It was purchased in 2017 by Centre City Partners LP, with plans for a $46 million renovation to include residence apartments, office spaces and retail shops.This building was added to the National Register of Historic Places on December 10, 1993.On Saturday, January 11, 2020, a number of the building's windows were blown out by powerful storm winds, resulting in the temporary closure of the neighboring Wright Stop Plaza, the downtown hub for the Greater Dayton Regional Transit Authority. At the time, the building was up for sale for more than four million dollars.On November 10, 2020, a large pane of glass from the building fell onto a nearby sidewalk, forcing barriers to be erected. The building has been vacant since the mid-2000s, changing ownership a couple of times during that period. Dayton city manager Shelley Dickstein expressed that the building may see development following completion of the renovation of the Dayton Arcade.