Oyster Point Marina/Park

The South San Francisco Ferry Terminal is the only operating ferry terminal in San Mateo County, California. Boats are operated by San Francisco Bay Ferry and connect the city of South San Francisco to the Oakland Ferry Terminal in Jack London Square as well as Alameda, California. Construction began in 2009 and ferry service started on June 4, 2012. While ferry service between San Francisco and ports to the south existed as far south as San Jose/Alviso during the 1800s, most passengers to Peninsula destinations took the San Francisco and San Jose Railroad after it was completed in 1864 as part of the transcontinental railway.

The San Francisco Baking Institute (SFBI) is a private, unaccredited culinary school in South San Francisco, California founded by Michel Suas and his wife Evelyne Suas in 1996. The school hosts bread and pastry classes for professional and amateur bakers, as well as baking instructors.

The Western Pipe and Steel Company (WPS) was an American manufacturing company that is best remembered today for its construction of ships for the Maritime Commission in World War II. It also built ships for the U.S. Shipping Board in World War I and took part in the construction of the giant Grand Coulee Dam project in the 1930s.

Sangamo Therapeutics, Inc. (previously known as Sangamo Biosciences, Inc.) is an American biotechnology company based in Brisbane, California. It applies cell and gene therapy to combat haemophilia and other genetic diseases.

The Dakin Building is an architectural award-winning class A office building on the San Francisco Bay in Brisbane, California. Serving as a corporate headquarters building for several companies of national prominence, it was built from the profits of the Garfield character whose licensed products of the R. Dakin Company division of Applause Toys soared in sales in the late 1980s. Located on Sierra Point, it became a landmark in the San Francisco Bay Area for its distinctive design and was nicknamed the Luke Skywalker building for its dramatic posture overlooking the bay, in contrast to a neighboring office building with a dark, ominous appearance that was nicknamed the Darth Vader building.

Butler Road station was a train station in South San Francisco, California, in operation until July 1983 on the Peninsula Commute, a commuter rail service run by Southern Pacific between San Francisco and communities on the San Francisco Peninsula. The Butler Road train shelter was built in 1926.

Colma Creek is a small creek that flows to the San Francisco Bay from its source in the Crocker Hills portion of San Bruno Mountain State and County Park, north of San Mateo County's Guadalupe Canyon Parkway, with contribution from April Brook on San Bruno Mountain proper, south of the Parkway. It flows southwest and makes a 90 degree bend in Daly City to flow southeastward, through Daly City, Colma, and South San Francisco to the bay. Its small delta is between South San Francisco and the San Francisco International Airport.The creek has a tributary stream named Twelvemile Creek, which joins it from the southwest along Westborough Blvd. in South San Francisco.

South San Francisco station is a Caltrain station in South San Francisco, California. The station is on the east side of the Bayshore Freeway (U.S. 101), east and south of the curved Grand Avenue overpass, and north of where the freeway crosses over the tracks. Downtown South San Francisco is to the west, across the freeway. It previously underwent a substantial modernization and expansion project, completed in January 2022.

Coast Guard Air Station San Francisco is a United States Coast Guard Air Station located 13 miles south of downtown San Francisco, California at the San Francisco International Airport in an unincorporated area of San Mateo County. The air station sits adjacent to the airport which consists of its own ramp, one hangar, an administration building and several other support structures.

Brisbane School District is a school district in California. It consists of Lipman Middle School, Brisbane Elementary School, and Panorama Elementary School.

South San Francisco is a city in San Mateo County, California, United States, located on the San Francisco Peninsula in the San Francisco Bay Area. The city is colloquially known as "South City". The population was 63,632 at the 2010 census.

The South San Francisco Hillside Sign is a historic sign on a hillside overlooking the city of South San Francisco in San Mateo County, California. It was created in the 1920s and was listed on the National Register of Historic Places in 1996. The sign is the main feature of Sign Hill Park, a city park which provides 30 acres (12 ha) of open space, almost 2 miles (3.2 km) of hiking trails, and access to the letters of the sign itself.The sign spells out "SOUTH SAN FRANCISCO THE INDUSTRIAL CITY" in white-painted concrete letters and is visible to drivers on northbound U.S. 101 and flights to San Francisco International Airport.