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The Mountain Springs Hotel is listed on the National Register of Historic Places and is located in Ephrata, Pennsylvania, at the corner of East Main Street and Spring Garden Street. It was originally built in 1848 as a summer resort, capitalizing on its natural spring water, and hosted a variety of high-profile guests including several Presidents. The resort lost its popularity in the early 20th century and fell into disrepair, but was eventually purchased and converted into the first hospital in the Ephrata area—serving from 1937 through 1949. It remained under private ownership and became dilapidated over the following decades, culminating in its complete closure in 1988 and the auctioning of its contents in 1991. The following decade was met with a variety of redevelopment proposals, and in the years around the turn of the 21st century it was decided that the property would be redeveloped with another hotel. The majority of the Mountain Springs Hotel was demolished in 2004, retaining a portion of the Konigmacher mansion. Today, a Hampton Inn hotel and Applebee's restaurant occupy the site alongside the restored building from the original Mountain Springs Hotel.

Eby Shoe Corporation, also known as Fleet-Air Corporation, is a historic factory building complex located at Ephrata, Lancaster County, Pennsylvania. The property includes three contributing buildings to the listing. Building "A" was built about 1900, and is a four-story, gable roofed brick building with a two-story flat roofed addition. Building "B" was built in 1919-1920, and is a three-story, gable roofed brick building measuring 48 feet wide and 115 feet deep. Building "C" was built in 1923, and is a four-story, steel frame building with a brick exterior. It measures 48 feet wide and 180 feet deep. The Eby Shoe Corporation closed in 1985.It was listed on the National Register of Historic Places in 1989.

Ephrata Commercial Historic District is a national historic district located at Ephrata, Lancaster County, Pennsylvania. The district includes 36 contributing buildings in the central business district of Ephrata. It has notable examples of the Queen Anne and Italianate architectural styles and buildings designed by noted Lancaster architect C. Emlen Urban. The oldest building dates to 1808 and is the Eagle Hotel. Other notable buildings include the I.G. Sprecher & Sons Hardware (1911), Richard Heitler House (1820), J.W. Yost Liquor Store (c. 1880), Ephrata Railroad Station (1887-1889), U.S. Post Office (1937), Ephrata National Bank (1925), and Grant and Wenger Feed Mill (1924). Located in the district is the separately listed Mentzer Building.It was listed on the National Register of Historic Places in 2006.

Mentzer Building is a historic commercial building located at Ephrata, Lancaster County, Pennsylvania. It was built in 1889, and is a three-story, brick building in the Queen Anne style. The building has housed school classrooms, barbershops, an electric supply store, meeting rooms, and retail clothing sales shops. The porch and entrance have been restored based on historical photographs. It was listed on the National Register of Historic Places in 1985. It is located in the Ephrata Commercial Historic District.

Connell Mansion is a historic home located at Ephrata, Lancaster County, Pennsylvania. It was built about 1860, and is a three-story, brick dwelling with a low hipped slate roof and octagonal cupola. It has a two-story, rear section with a one-story extension, both with gable roofs. Also on the property are a contributing carriage house and frame privy.It was listed on the National Register of Historic Places in 1979.

Ephrata ( EF-rə-tə; Pennsylvania German: Effridaa) is a borough in Lancaster County, Pennsylvania, United States. It is located 42 miles (68 km) east of Harrisburg and about 60 miles (97 km) west-northwest of Philadelphia and is named after Ephrath, the former name for current-day Bethlehem. In its early history, Ephrata was a pleasure resort and an agricultural community. Ephrata's population has steadily grown over the last century. In 1900, 2,452 people lived there, and by 1940, the population had increased to 6,199. The population was 13,818 at the 2020 census. Ephrata is the most populous borough in Lancaster County. Ephrata's sister city is Eberbach, Germany, the city where its founders originated.

Ephrata Township is a township in northeastern Lancaster County, Pennsylvania, United States. The population was 10,391 at the 2020 census.

Peter and Catherine Reyer Farmhouse is a historic home located at Ephrata Township, Lancaster County, Pennsylvania. It was built in 1792, and is a two-story, four bay by two bay, limestone Germanic dwelling. It was remodeled about 1875, into a Pennsylvania style farmhouse.It was listed on the National Register of Historic Places in 1996.

The Hibshman Farm, also known as the Schantz Farm, is an historic home and farm complex which is located in Ephrata Township, Lancaster County, Pennsylvania. It was listed on the National Register of Historic Places in 1980.

The Bitzer's Mill Covered Bridge is a covered bridge that spans the Conestoga River in Lancaster County, Pennsylvania, United States. It is the oldest bridge in the county still in use. A county-owned and maintained bridge, its official designation is the Big Conestoga #2 Bridge. The bridge is also called Martin's Mill Bridge, Eberly's Cider Mill Covered Bridge, and Fiand's/Fiantz's Covered Bridge. The bridge has a single span, wooden, double Burr arch trusses design with the addition of steel hanger rods. The deck is made from oak planks. Added later, secondary steel I-beams support the bridge from underneath. The bridge is painted red on the outside, the traditional color of Lancaster County covered bridges. The inside of the bridge is not painted. Both approaches to the bridge are painted in the traditional white color. As of July 2006, the bridge has some damage to its sides including some missing or broken panels. The bridge, which has a 10 foot 6 inch height restriction, was damaged again on November 20, 2023, this time by a 13 feet 4 inches tall semi-trailer which got stuck in the bridge and allegedly caused further damage by attempting to back out after being stuck.The bridge's WGCB Number is 38-36-04. In 1980 it was added to the National Register of Historic Places as structure number 80003516. It is located at 40°8′25.8″N 76°9′7.2″W (40.1405, -76.1520) near the junction of U.S. Route 222 and U.S. Route 322 southeast of Ephrata in West Earl Township. The bridge can be reached by going approximately 1.5 miles (2.4 km) south from U.S. Route 322 on Cabin Drive which becomes Conestoga Creek Road. A left onto Cider Mill Road leads straight to the bridge, which is visible from the intersection.

Cocalico Creek is a 27.2-mile-long (43.8 km) tributary of the Conestoga River in Lebanon and Lancaster counties in Pennsylvania in the United States. The source is at an elevation of 1,320 feet (400 m) near Stricklerstown in Millcreek Township, Lebanon County. The mouth is the confluence with the Conestoga River at an elevation of 278 feet (85 m) at Talmage in West Earl Township, Lancaster County.The name of the creek comes from the Lenape, meaning "snake dens". It comes from the Lenape word Gookcalicunk (pronounced "Gook Cal-eek Unk), which means "Snake Sleep Place" in English. The Lenape considered modern East Cocalico, West Cocalico, Clay, Warwick, Elizabeth, and Penn townships in Lancaster County, Mill Creek Township in Lebanon County, and the Middle Creek Wildlife Management Area as part of Gookcalicunk. Cocalico Creek flows south for 10 miles (16 km), then southwest 16 miles (26 km). The Cocalico Creek watershed has a total area of 140 square miles (360 km2) and is part of the larger Chesapeake Bay drainage basin via the Susquehanna River.

The Bucher's Mill Covered Bridge or Butcher's Mill Covered Bridge is a covered bridge that spans Cocalico Creek in Lancaster County, Pennsylvania, United States. After the Landis Mill Covered Bridge, it is the second shortest covered bridge in the county. A county-owned and maintained bridge, its official designation is the Cocalico #2 Bridge. The bridge has a single span, wooden, double Burr arch trusses design with the addition of steel hanger rods. The deck is made from oak planks. It is painted red, the traditional color of Lancaster County covered bridges, on both the inside and outside. Both approaches to the bridge are painted in the traditional white color. The bridge's WGCB Number is 38-36-12. In 1980 it was added to the National Register of Historic Places as structure number 80003514. It is located at 40°12′28.2″N 76°8′4.8″W (40.20783, -76.134667) to the northeast of Ephrata, Pennsylvania off Pennsylvania Route 272 on Cocalico Creek Road.