Irell & Manella Graduate School of Biological Sciences

City of Hope is a private, non-profit clinical research center, hospital and graduate school located in Duarte, California, United States. The center's main campus resides on 110 acres (45 ha) of land adjacent to the boundaries of Duarte and Irwindale, with a network of clinical practice locations throughout Southern California, satellite offices in Monrovia and Irwindale, and regional fundraising offices throughout the United States.City of Hope is best known as a cancer treatment center. It has been designated a Comprehensive Cancer Center by the National Cancer Institute. City of Hope has also been ranked one of the nation's Best Cancer Hospitals by U.S. News & World Report for over ten years and is a founding member of the National Comprehensive Cancer Network. City of Hope played a role in the development of synthetic human insulin in 1978. The center has performed 13,000 hematopoietic stem cell transplants as of 2016 with patient outcomes that consistently exceed national averages.

The Beckman Research Institute of City of Hope (BRI) is a not-for-profit medical research facility located at and partnering with the City of Hope National Medical Center in Duarte, California, United States. It is dedicated to studying normal and abnormal biological processes which may be related to cancer, diabetes, HIV/AIDS and other life-threatening diseases. Both basic and clinical research are carried out in cooperation with the City of Hope National Medical Center. The institute itself is organized into more than 20 departments and divisions. As of 2021, the director is Steven T. Rosen. The Beckman Research Institute also hosts the Irell & Manella Graduate School of Biological Sciences whose founding dean was Arthur Riggs.

Duarte/City of Hope station is an at-grade light rail station on the A Line of the Los Angeles Metro Rail system. It is located at the intersection of Duarte Road and Highland Avenue in Duarte, California, after which the station is named, along with the City of Hope National Medical Center located across the street from the station. This station opened on March 5, 2016, as part of Phase 2A of the Gold Line Foothill Extension Project.

Duarte High School is a public high school located in Duarte, California and is part of Duarte Unified School District. Duarte High School currently has 950 students enrolled. Their mascot is the falcon. It was recognized as a California Distinguished School in 2007 for its high test scores and academic achievement.Duarte High was recognized in Newsweek as one of the top public high schools in the United States. See below for detailed rankings.

Santa Fe Dam is a flood-control dam on the San Gabriel River located in Irwindale in Los Angeles County, California, United States. For most of the year, the 92-foot (28 m)-high dam and its reservoir lie empty, but can hold more than 45,000 acre-feet (56,000,000 m3) of water during major storms. During the dry season, the basin behind the dam is used for groundwater recharge, as well as various recreational activities.

Irwindale is a city in the San Gabriel Valley, in Los Angeles County, California. The population was 1,422 at the 2010 census, down from 1,446 at the 2000 census. The ZIP Codes serving the area are 91010, which is shared with Duarte, 91702, which is shared with Azusa, and 91706, which is shared with Baldwin Park. With relatively few residents, Irwindale consists mostly of rock quarries, which are the major revenue source for the city. The Irwindale Event Center is also located in the city, as is the Santa Fe Dam Recreation Area near the San Gabriel River, a plant of the Miller Brewing Company, and a plant of the Huy Fong Foods sriracha sauce company. The city became the new permanent site for the annual Renaissance Pleasure Faire of Southern California in 2005, after it moved from its previous home at the Glen Helen Regional Park in Devore. Irwindale, is a full-service city, it has local police and library services. There is a skate park, a teen center, a senior center, public gymnasium and a public pool. The majority of the housing is found on the southeastern portion of the city, near Arrow Highway and north of Cypress Street near Irwindale Avenue. There is also a tract of housing on the southeastern corner of Meridian St in the northwestern portion of the city, being distant from the rest of the housing.

Duarte () is a city in Los Angeles County, California, United States. As of the 2020 census, the city population was 21,727. It is bounded to the north by the San Gabriel Mountains, to the north and west by the cities of Bradbury and Monrovia, to the south by the city of Irwindale, and to the east by the cities of Irwindale and Azusa. Duarte is located on historic U.S. Route 66 which today follows Huntington Drive through the middle of the city. The town is named after Andrés Avelino Duarte, a Californio ranchero who founded the community.

Monrovia Airport, also called the Foothill Flying Field, was an American airport in Monrovia, California active from 1928 to 1952.

Bradbury is a city in the San Gabriel Valley region of Los Angeles County, California, United States. It is located in the foothills of the San Gabriel Mountains below Angeles National Forest. Bradbury is bordered by the city of Monrovia to the west and south, and Duarte to the south and east. The population was 1,048 at the 2010 census, up from 855 at the 2000 census. The city has three distinct areas—the Bradbury Estates, which is a gated community consisting of 5-acre (20,000 m2) minimum estates; Woodlyn Lane, which is also a gated community with minimum 2-acre (8,100 m2) lots; and the balance of the city, which is not gated, which has lots generally ranging in size from 7,500 square feet (700 m2) to 1-acre (4,000 m2). A significant portion of the properties in Bradbury Estates and Woodlyn Lane are zoned for horses, and several horse ranches still exist within these communities today.

The Renaissance Pleasure Faire of Southern California (RPFS) is a Renaissance faire that takes place at the Santa Fe Dam Recreation Area in Irwindale, California. It opened in the spring of 1963 and has been an annual event since then. Presently owned by Renaissance Entertainment Productions (REP), it is a commercial reenactment of a 1580s market faire at Port Deptford, a waterfront town in Elizabethan era England. The Faire is generally open from the first weekend of April through the weekend before Memorial Day.

The Irwindale Speedway & Event Center (a.k.a. Irwindale Speedway, Irwindale Dragstrip, or "The House of Drift") is a motorsports facility located in Irwindale, California, United States. It opened on March 27, 1999 under the official name Irwindale Speedway. Toyota purchased the naming rights to the facility in 2008, and from that time until 2011 it was also known as the Toyota Speedway at Irwindale.The speedway features banked, paved 1/2- and 1/3-mile oval tracks and a 1/8-mile drag strip. The property is primarily used for NASCAR races such as ARCA Menards Series West and Whelen All-American Series events. In late 2011, NASCAR announced it was dropping Toyota Speedway from its schedule. The company that managed the track, Irwindale Speedway LLC, filed Chapter 7 bankruptcy on February 13, 2012.In January 2013, it was announced that the track would be re-opening as the Irwindale Event Center, and would operate as a Whelen All-American Series venue for the 2013 season. For the past decade, the Formula D Championship Series had featured sold out events at the venue. In 2015, plans were made to demolish Irwindale Speedway and build an outlet mall on the site of the track. On August 9, 2017 it was officially announced that Jim Cohan, CEO of Team 211 Entertainment, who operated the track under the name of Irwindale Event Center, would cease operation. On December 29, 2017 it was announced that the track would not close in January 2018 as former Irwindale Late Model driver and track champion Tim Huddleston, along with K&N West team owner Bob Bruncatti, took over management of the speedway to have it remain open.

South Monrovia Island () is a census-designated place in Los Angeles County, California. It sits at an elevation of 384 feet (117 m). It is bounded to the west and north by Monrovia, to the east by Duarte, and to the south by Irwindale. The 2010 United States census reported that South Monrovia Island's population was 6,777.