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The Center for Human Reproduction (CHR) is a fertility center located in New York City. It was founded by the obstetrician-gynecologist Norbert Gleicher in 1981.

The Upper East Side Historic District is a landmarked historic district on the Upper East Side of New York City's borough of Manhattan, first designated by the city in 1981. It was listed on the National Register of Historic Places in 1984. Its boundaries were expanded in 2010.The district includes all of the Fifth Avenue properties bordering Central Park from 59th to 78th Street; both sides of Madison Avenue from 61st Street to 77th Street; both sides of Park Avenue from just below 62nd street to 72nd Street; and portions of both sides of Lexington Avenue from 63rd Street to 75th Street.The district is home to a number of buildings individually listed on the National Register, including the Gertrude Rhinelander Waldo Mansion and the Sara Delano Roosevelt Memorial House, as well as edifices that are more recent additions like the Edmond J. Safra Synagogue — a 2003 building designed in an "artful synthesis of the composition, details and material palette of the Beaux-Arts style," to complement the historic buildings that surround it.

The Frick Collection is an art museum in New York City. Its permanent collection (normally at the Henry Clay Frick House, currently at the Frick Madison) features Old Master paintings and European fine and decorative arts, including works by Bellini, Fragonard, Goya, Holbein, Rembrandt, Titian, Turner, Velázquez, Vermeer, Thomas Gainsborough, and many others. The museum was founded by the industrialist Henry Clay Frick (1849–1919), and its collection has more than doubled in size since opening to the public in 1935. The Frick also houses the Frick Art Reference Library, a premier art history research center established in 1920 by Helen Clay Frick (1888–1984).

The Frick Art Reference Library Photoarchive is a study collection of more than one million photographic reproductions of works of art from the fourth to the mid-twentieth century by over 40,000 artists trained in the Western tradition located in the Frick Art Reference Library on the Upper East Side of Manhattan. It was founded in 1920 by Helen Clay Frick, the daughter of industrialist Henry Clay Frick, to facilitate object-oriented research. The documentation it offers records the essential elements of the biography of the work of art: the artist, title, present owner, as well as historical information such as changes of attribution, ownership and condition, all of which are essential for the study of the history of art.

The Frick Art Reference Library is the research arm of The Frick Collection. Its reference services have temporarily relocated to the Breuer building at 945 Madison Avenue, called Frick Madison, during the renovation of the Frick's historic buildings at 10 East 71st Street (between Madison and Fifth Avenue) in New York City. The library was founded in 1920 and it offers public access to materials on the study of art and art history in the Western tradition from the fourth to the mid-twentieth century. It is open to visitors 16 years of age or older and serves the greater art and art history research community through its membership in the New York Art Resources Consortium (which also includes the libraries of the Brooklyn Museum and The Museum of Modern Art). Within the library is the Center for the History of Collecting—a research organization that supports the study of the formation of collections of fine and decorative arts, both public and private, from Colonial times to the present through its fellowships, symposia, and publications.

The Arthur Curtiss James House was a mansion located on 39 East 69th Street in New York City. It was constructed for Arthur Curtiss James.

The C. Ledyard Blair House was a mansion on 2 East 70th Street, at the corner with Fifth Avenue, on the Upper East Side of Manhattan in New York City. It was constructed for banker C. Ledyard Blair and designed by Carrère & Hastings. The house was constructed from 1914 to 1917 and occupied almost 7,300 square feet (680 m2). It was sold and demolished in 1927 to make way for an apartment house.

The Henry Clay Frick House was the residence of the industrialist and art patron Henry Clay Frick in New York City. The mansion is located between 70th and 71st Street and Fifth Avenue on the Upper East Side of Manhattan. It was constructed in 1912–1914 by Thomas Hastings of Carrère and Hastings. It was transformed into a museum in the mid-1930s and houses the Frick Collection and the Frick Art Reference Library. The house and library were designated a National Historic Landmark in 2008 for their significance in the arts and architecture as a major repository of a Gilded Age art collection.

The George Blumenthal House was a mansion located on 50 East 70th Street in New York City. It was constructed for George Blumenthal.

The Smolin Gallery was an avant-garde art venue and gallery at 19 East 71st Street in New York City, at its peak in the 1960s. It was known for its involvement with installation art, performance art and experimental art, and was best known for the Allan Kaprow assemblage performance of September 11–12, 1962 entitled "Words", believed to be the first allowing the audience to participate in an art gallery context. Kaprow "used two continual rolls of cloth with words from poems, newspapers, comic and telephone books" during which the audience were asked to "tear off the words, staple them together, write notes, even attack and hack them". Verbal fragments were pasted on the walls from floor to ceiling. In April 1963, Lima and Tony Towle gave their first public recital at the gallery. In May 1963 the Smolin Gallery sponsored innovative Wolf Vostell events on TV. Do it yourself Dé-coll/age featured visitors to the gallery who were encouraged to use their own DIY liquids to create poster art on the walls and Wolf Vostells installation Television Décollage (6 TV Dé-coll/age) was shown. The gallery sponsored the Yam Festival and served as an information center during the event. The Yam Festival, held at George Segals farm, in New Brunswick was venue on May 19, 1963 to actions and Happenings by artists including Dick Higgins, Allan Kaprow, La Monte Young and Wolf Vostell who made the happening TV Burying. In 1965, Doris Totten Chase gave her first solo New York exhibition at the Smolin Gallery, featuring paintings on wood. She exhibited a series of small painted sculptures inset with hinged sections which opened to reveal additional painted sections.

St. James' Church is an Episcopal parish church located at the intersection of Madison Avenue and 71st Street on the Upper East Side of Manhattan, New York City. Founded in May 1810 as a summer chapel for New Yorkers with country homes north of the then city, it has grown into one of the largest Episcopal churches in New York City. In addition to worship, it has programs for children and young families, youth and young adults, as well as a music program and a devotion to mission and service in the community.In 2020, it reported 1,546 members, average attendance of 776, and $2,822,898 in plate and pledge income.

The Explorers Club is an American-based international multidisciplinary professional society with the goal of promoting scientific exploration and field study. The club was founded in New York City in 1904, and has served as a meeting point for explorers and scientists worldwide. The Explorers Club hosts an annual dinner to honor accomplishments in exploration, which is known for its adventurous, exotic cuisine.