1072 West Peachtree Street

On May 3, 2023, a mass shooting occurred at a Northside Hospital facility in Midtown Atlanta, Georgia, United States. Five people were shot, one fatally and three critically, before a male suspect, Deion Patterson, fled the scene. He was apprehended eight hours later and charged with one count of murder and four counts of aggravated assault.

The Turner Broadcasting tower was a 314.3-meter (1,031 ft) free-standing lattice tower in Atlanta, Georgia. It was located next to the Downtown Connector between Spring, West Peachtree, 10th and 12th Streets in Midtown. The tower had a triangular cross-section and was built on the site of a previous four-sided broadcast tower built for WAGA-TV 5 and to serve WJRJ-TV which was founded by Rice Broadcasting Inc. which was owned by a local Atlanta entrepreneur, Jack M. Rice, Jr. It is the tallest freestanding structure to ever be voluntarily removed in the United States and second tallest in the world.

Williams Street Productions, LLC, d/b/a Williams Street and formerly known as Ghost Planet Industries, is an American animation and live action television production studio owned by the Warner Bros. Television Studios division of Warner Bros., a unit of Warner Bros. Discovery. The studio is the in-house production arm of Adult Swim (the programming block on Cartoon Network). Mike Lazzo and Keith Crofford oversaw operations for the building for most of its existence. On December 16, 2019, co-founder Lazzo retired from the company, with business partner and co-founder Crofford retiring the following year. Michael Ouweleen was named president in 2020.

Regions Plaza is a 24-floor office high-rise located at 1180 West Peachtree Street in Atlanta, Georgia. The building was completed in 2001 and renovated in 2014. The building currently serves as the Georgia headquarters for Regions Financial Corporation. The building is located on the corner of 14th Street and West Peachtree Street which is the latitude line that defines the center of Midtown. Its parking garage entrance is located at 1217 Spring Street. Prior to 2013, the building was known as Atlantic Center Plaza.

One Atlantic Center, also known as IBM Tower, is a skyscraper located in Midtown Atlanta, Georgia. It is the third tallest building in Atlanta.

The Federal Reserve Bank of Atlanta, (informally referred to as the Atlanta Fed and the Bank), is the sixth district of the 12 Federal Reserve Banks of the United States and is headquartered in midtown Atlanta, Georgia. The Atlanta Fed covers the U.S. states of Alabama, Florida, and Georgia, the eastern two-thirds of Tennessee, the southern portion of Louisiana, and southern Mississippi as part of the Federal Reserve System. Along with its Atlanta headquarters, the Banks operates five branches with the sixth district, which are located in Birmingham, Jacksonville, Miami, Nashville, and New Orleans. These branches provide cash to banks, savings and loans, and other depository institutions; transfer money electronically; and clear millions of checks.In addition to supporting the U.S. financial system, the Atlanta Fed carries out the supervision and regulation of the banks operating within the sixth district. It also is a source of research and expertise for public and private decision makers within the district. In recent years, researchers within the Atlanta Fed have innovated new tools to gauge the health of the macro U.S. economy, the two most notable are GDPNow and Wage Growth Tracker.The Atlanta Fed is currently led by Dr. Raphael Bostic, who was appointed in 2017 and is a member of the Federal Open Market Committee (FOMC), the committee that makes key decisions about interest rates and the growth of the United States money supply.

My Sister's Room (MSR) is a lesbian bar in Atlanta, Georgia. It is one of the few remaining lesbian bars in the nation. It was opened in 1996 by Susan Musselwhite and has been lesbian-owned and operated bar since 1996. Pictures of My Sister's Room in the 1990s are in Emory University's permanent photo collection.MSR originally was located in the Midtown area of Atlanta. It then moved to the popular lesbian Atlanta suburb Decatur, Georgia from 1997-2006 until the building was sold to build condos and they moved to the bar district of East Atlanta Village. In 2011 the bar was sold to Jen-Chase Daniels and Jami Siden. In the summer of 2015, My Sister's Room moved back to a larger space in the most LGBT-friendly part of Midtown Atlanta, also referred to as the "gayborhood". It is currently a two-story dance venue.MSR established the Pensacola Memorial Weekend Pride event "Sexacola" that caters to lesbian party goers.

Ten Peachtree Place is a high-rise class A office building in midtown Atlanta, Georgia. The building was designed by Michael Graves and completed in 1989. It currently serves as the headquarters for Southern Company Gas. The building is notable for its 30 ft (9.1 m) high arch and red granite exterior that contrasts with the building's dark windows.

Symphony Center was a proposed concert hall in Atlanta, Georgia that would have been the new home of the Atlanta Symphony Orchestra. The site for the new structure was to be in Midtown on 14th Street just south of the current Symphony Hall in the Woodruff Arts Center. Architect Santiago Calatrava was selected to design the facility and delivered a design that would serve as a "postcard" for the city. The design was unveiled in 2005, but was cancelled in 2008 due to funding issues. The ASO now plans to build a new hall at the Woodruff Arts Center, at 15th Street and Peachtree Street.In May 2014, the Woodruff Arts Center sold the property to a group of New York City-based developers, and it is currently the site of the Opus Place development.

The GLG Grand building is a 186-meter (609-foot) tall skyscraper in Midtown Atlanta. The Art Deco-inspired, pyramid-capped tower is 53 stories tall and was finished in 1992. The bottom third of it is the Four Seasons Hotel Atlanta, which includes 244 guest rooms and is the only 5-star hotel in Midtown. It is the eleventh-tallest skyscraper in Atlanta. The building was designed by Rabun Hogan Ota Rasche Architects, and built by Beers Construction of Atlanta. The GLG Grand building is notable for several reasons. First, it was Atlanta's first mixed-use skyscraper, incorporating hotel, office and condominiums into one building. Several skyscrapers of the same type are on the drawing boards, but they have yet to break ground. Second, it was a dismal failure for its developer, G. Lars Gullstedt (1935-2015) of Sweden, who made headlines in Atlanta in 1991 by buying up huge parcels of run-down land in Midtown and proposing a massive multi-block mixed-use development to be called "GLG Park Plaza." The GLG Grand, which took its name from Gullstedt's initials, was an unrelated development of Gullstedt's on 14th Street, several blocks north. The building opened in 1992 to a depressed real estate market, and its condominiums and office space sat largely vacant. Gullstedt, who was also a developer in Sweden, was forced into bankruptcy there, and lost control of all of his Atlanta holdings including this building. Only later, in the mid-2000s, did his former Midtown parcels begin to be developed, coming just before the economic downturn of the financial crisis of 2007–2008. The hotel in the building was originally called the GLG Grand Hotel, then the Occidental Grand Hotel, before becoming the Four Seasons Hotel Atlanta in the late 1990s.

Four Seasons Hotel Atlanta is a hotel in Atlanta, Georgia, United States. It is part of Toronto-based Four Seasons Hotels and Resorts. The hotel is located in the Midtown Atlanta, and occupies the lower third of the GLG Grand building.

Midtown is an underground metro station in Atlanta, Georgia, serving the Red and Gold lines of the Metropolitan Atlanta Rapid Transit Authority (MARTA) rail system. Located in Midtown Atlanta, 5,644 daily fares were collected at the gates as of 2013. It provides access to the Midtown business and financial district, The Federal Reserve Bank of Atlanta, Margaret Mitchell House, Georgia Tech, and Piedmont Park. It provides connecting bus service to Cumberland Mall, Georgia Tech, Emory University, Emory Decatur Hospital, Grady Memorial Hospital, The District at Howell Mill, Atlanta Medical Center, Ansley Mall, Lindbergh Center, Atlanta Botanical Garden, and Turner Broadcasting headquarters.