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WNCT (1070 kHz) is an AM radio station broadcasting a beach music format, as "Beach, Boogie and Blues". Licensed to Greenville, North Carolina, United States, the station serves the Greenville-New Bern area. The station is currently owned by Curtis Media Group Inc.

John Paul II Catholic High School (JPII), located in Greenville, North Carolina is a four-year private coeducational college-preparatory Catholic high school.

ECU Health EastCare is the critical care mobile air and ground transport of ECU Health at ECU Health Medical Center. It serves 31 counties in Eastern North Carolina. It is sponsored by ECU Health Medical Center and The Brody School of Medicine at East Carolina University. ECU Medical Center is the only level 1 trauma center east of Raleigh. EastCare's five full-time air ambulances constitute the largest air medical program in North Carolina and can serve a radius of 230 nautical miles (430 km; 260 mi) around Greenville without refueling.Joanna Adams is the current Medical Director for ECU Health EastCare and Trey Labrecque is the Program Director.ECU Health EastCare can be dispatched for a number of causes, including: trauma, burn, neonatal, high risk pregnancy, hyperbaric medicine, stroke and myocardial infarction. ECU Health EastCare is most often sent for cardiac patients, followed by trauma, pediatric and neonatal patients. EastCare boasts an excellent safety record. It's only major mishap occurred on January 8, 1987. In January 2012, Vidant Medical Transport changed its name from EastCare as part of a system wide renaming initiative. In October 2014, Vidant Medical Transport became Vidant EastCare. In May 2022, Vidant EastCare became ECU Health EastCare.

The College of Allied Health Sciences is a college at East Carolina University. The school comprises all allied health majors except those offered by the College of Nursing.

ECU Health Medical Center (previously Pitt County Memorial Hospital and Vidant Medical Center) is a hospital located in Greenville, North Carolina. It is the primary teaching hospital for East Carolina University's Brody School of Medicine and is the flagship medical center for ECU Health. ECU Health is a Level 1 Trauma Center, one of 6 in the state of North Carolina. It is the only level I trauma center east of Raleigh, and thus is the hub of medical care for a broad and complicated rural region of over 2 million people. ECU Health Medical Center is the largest employer in Eastern North Carolina and 20th overall in the state.ECU Health Medical Center was licensed for 974 beds in fiscal year 2020. Of the 974 beds, 847 are general beds, 75 are rehab beds, and 52 are psychiatric beds. The hospital has 37 operating rooms: 26 rooms are Shared Inpatient/Ambulatory Surgery; four rooms are C-Section; three rooms are Other Inpatient; four rooms are Endoscopy.The facility was originally known as Pitt Community Hospital and was located near downtown Greenville. In 1934, it changed to Pitt General Hospital, and then again to Pitt County Memorial Hospital (PCMH) in 1949. The hospital moved to West Greenville in 1951, and then to its current location in 1977. On August 17, 2011, it was announced PCMH would change its name to UHS Medical Center. The change failed to occur on the planned October 1, 2011. The UHS brand was taken, so the hospital system instead finally changed its name to Vidant Medical Center. At the time, Vidant Health claimed that Vidant is derived from the root "Vi" that is associated with "life" in Latin, and in fact "Vida" literally means "life" in Spanish. On January 3, 2022, Vidant Health Announced that it would be rebranding as ECU Health, but it would take several months for the changes to become noticeable.

The Brody School of Medicine at East Carolina University (BSOM) is a public medical school located in Greenville, North Carolina, United States. It offers a Doctor of Medicine program, combined Doctor of Medicine / Master of Public Health and Doctor of Medicine / Master of Business Administration programs, and standalone Doctor of Philosophy and Master of Public Health programs. Brody is a national leader in family medicine, ranking No. 1 in North Carolina and No. 2 nationally in the percentage of graduates who choose careers in family medicine, based on the 2017 American Academy of Family Physicians report on MD-granting medical schools. Brody ranks in the top 10 percent of U.S. medical schools for graduating physicians who practice in the state, practice primary care and practice in rural and underserved areas. Brody graduates currently practice in 83 of North Carolina's 100 counties. The Brody School of Medicine was first appropriated funds from the General Assembly in 1974. Under the leadership of former Chancellor Leo Warren Jenkins, the first class of 28 students enrolled in 1977. The school's primary mission is "to increase the supply of primary care physicians to serve the state, to enhance the access of minority and disadvantaged students in obtaining a medical education and to improve health status of citizens in eastern North Carolina." Under the leadership of Dean Michael Waldrum and Executive Dean Jason Higginson, today Brody School of Medicine has a student body of about 470 students and around 450 faculty members and researchers. BSOM organizes research through more than a dozen research centers and institutes, receiving around US $30 million annually in externally funded grants and contracts. BSOM is ranked as a "top medical school" by U.S. News & World Report in primary care, rural medicine, and family medicine.

Spencer Harris House, also known as the William T. Harris Homeplace, is a historic home located near Falkland, Pitt County, North Carolina. It was built about 1855, and is a two-story, three-bay, double pile Greek Revival style frame dwelling. It is sheathed in weatherboard siding, has a low hipped roof, and rests on a brick pier foundation.It was listed on the National Register of Historic Places in 2005.

Pitt County Schools is a school system located in Pitt County, North Carolina. The central office is located in Greenville. It operates one pre-kindergarten school, 16 elementary schools, six K–8, seven middle schools and six high schools.

Guy Smith Stadium is a sports stadium in Greenville, North Carolina. It is primarily used for baseball and is the home of the Greenville Yard Gnomes, a collegiate summer baseball team in the Coastal Plain League. Guy Smith Stadium was built by the Works Project Administration for $50,000 in 1939 (equivalent to $1,052,000 in 2022). The ballpark is located within Guy Smith Park at 1051 Moye Boulevard. In 2022, the baseball field at the stadium was officially named Ronald “RV” Vincent Field for the long-time JH Rose High School baseball coach who is the all-time winningest coach in North Carolina high school baseball history.The Greenville Greenies played minor league baseball at the stadium as members of the Coastal Plain League (Class D) (1939–1941, 1946–1951). The Greenville Yard Gnomes will start playing collegiate summer baseball at the stadium in the current Coastal Plain League with the 2024 season. Stadium renovations for the 2024 season, at a cost of $1 million, include new seats, additional restroom facilities and concessions, a new hitting tunnel, and a new batting cage.

Greenwreath, also known as the Foreman House, is a historic home located near Greenville, Pitt County, North Carolina. It was built around 1780, and is a 2+1⁄2-story, five bay frame dwelling with beaded siding and a exterior end chimneys. It was built in stages starting with a hall and parlor two room house in 1780, then extended to add a new front room around 1791 forming an L-configuration, and extended again with the federal 2+1⁄2-story structure being built in front of the original house around 1820 and attached to it so that the original house now forms a rear shed wing. Also on the property are the contributing tenant house, outbuilding, and a small Victorian-period brick ice house.It was added to the National Register of Historic Places in 1982.

Oakmont, also known as the William Albion Dunn House, is a historic home located at Greenville, Pitt County, North Carolina. It was designed by the architectural firm Benton & Benton and built in 1930. It is a two-story, five bay Colonial Revival frame dwelling with projecting frame wings, a screened porch and porte cochere and an open porch and rear sun room. Also on the property are the contributing garage (c. 1931), playhouse (c. 1931), and house site.It was added to the National Register of Historic Places in 2001.

South Central High School is a public high school in Winterville, North Carolina. It is the sixth high school in Pitt County's school system.