San Isidoro y San Leandro Western Orthodox Catholic Church of the Hispanic Mozarabic Rite

The Lillian Wald Houses are a NYCHA housing project on the Lower East Side of Manhattan that honors the housing advocate of the same name. The cornerstone was laid on East Sixth Street and Avenue D in 1947 following a change in state financing laws for which Lillian Wald campaigned.Construction of the Houses led to the end of Manhattan Street, previously a shortcut between East Third and East Houston Streets.

Bullet Space is a legalized squat, artists’ collective and art gallery on the Lower East Side of New York City, founded in 1986 by Andrew and Paul Castrucci, among others. In 2009, it was legalized by the city.

New Explorations into Science, Technology and Math, abbreviated NEST+M, is a public school located on the Lower East Side of the Manhattan borough of New York City, New York, and is under the supervision of the New York City Department of Education, serving grades kindergarten through 12th grade (the only K-12 public school in Manhattan).The school exclusively enrolls New York City resident K–3 children scoring within the 97th, 98th, or 99th percentile and sixth-graders at the 95th percentile nationwide in standardized tests administered by the New York City Department of Education for their Gifted & Talented Program. It is one of only five such New York citywide programs where qualified elementary or middle school students from any school district in any borough may enroll, and also the only program with a dedicated facility (the other four programs share schools with the general education student population) and the only program serving grades K through 12. Prospective 9th and 10th-grade students apply through the NYC High School Application Process as well as their entrance exam. As of September 2017, Principal Mark Berkowitz eliminated the NEST+m entrance exam and published the new rubric on the NEST+m website. In April 2020, Principal Mark Berkowitz resigned and accepted a position as Principal at Pelham Memorial High School located in Pelham, NY. Meaghan Lynch became the interim acting principal on July 1, 2020.

Bracetti Plaza, or Mariana Bracetti Plaza, is a public housing development built and maintained by the New York City Housing Authority in Alphabet City, a section of the East Village neighborhood of Manhattan. The development is named after Mariana Bracetti (1825-1903), a legendary Puerto Rican woman who was known as the "Arms of Gold", and who was the first to craft the Boriquas Latin Cross, Puerto Rico's first flag. The flag was designed by Dr. Ramon Emeterio Betances, and is still a symbol of the Puerto Rican independence movement.Bracetti Plaza is a seven-story building on grounds measuring 1.02 acres (4,100 m2), at 251 East 3rd Street, or 290 East 4th Street. The development has 108 apartments housing approximately 312 people. Its neighborhood, the East Village, was formerly included in the Lower East Side, and is still considered the Lower East Side by some, but now the border is generally drawn at Houston Street. The block it sits in is bordered by Avenue B to the west, Avenue C to the east, East 3rd Street to the south, and East 4th Street to the north.Bracetti Plaza was completed on May 31, 1974. It is serviced by the New York City Police Department's Ninth Precinct, and is governed by Manhattan Community Board 3. As of 2010, no one is serving as the Resident Association President for Bracetti Plaza. If someone were, he or she would be a member of the Manhattan South District Citywide Council of Presidents.

Umbrella House is a former squat and a Housing Development Fund Corporation in New York City's East Village, at 21-23 Avenue C. The squat, formed in 1988, was known for its political engagement and high level of collective organization among its members. In 2010, the building officially became a housing cooperative.

Green Oasis Community Garden & Gilbert's Sculpture Garden, also known as Green Oasis Community Garden, is a 17,787 square foot community garden and sculpture garden at 372 East 8th Street, located in the East Village of Manhattan, New York City.

The Stone is a not-for-profit experimental music performance space located in the Greenwich Village neighborhood in New York City. It was founded in April 2005 by John Zorn, who serves as the artistic director. It was named for the late Irving Stone, an "inveterate concertgoer" in the New York City music community.

Carmen Pabón del Amanecer Jardín, also known as Carmen's Garden and El Bello Amanecer Boriqueño Garden, is a 4,635-square-foot (430.6 m2) community garden at 117 Avenue C, in the East Village of Manhattan, New York City. Carmen Pabón del Amanecer Jardín is named after Carmen Pabon, a Lower East Side poet and gardener who died in 2016 at the age of 95.

Jardin de la Esperanza or Esperanza Garden was a community garden started in 1978 by Alecia Torres, a resident of New York City's Lower East Side, who began clearing rubble and trash out of an empty lot on East 7th Street, close to Ave C. The garden, later on, became a community space for growing medicinal plants, tending chickens, and a safe space for children to play.

The World was a large nightclub in New York City, which operated from the early 1980's until 1991 at 254 East 2nd Street, in Manhattan's East Village neighborhood. The venue, which included a secondary establishment called "The It Club," was housed in a former catering hall and theater. The World attracted a clientele that was economically, racially, and sexually diverse, and included artists, celebrities, and fashion designers, such as Keith Haring, Afrika Bambaataa, Madonna, Brooke Shields, Prince, Stephen Sprouse, RuPaul, and Carolina Herrera, together with banjee boys and members of voguing housesAn early incubator of New York's house music and club kid scenes, the World helped launch the careers of several prominent nightlife figures, including Michael Alig, DJ Larry Tee, DJ David Morales, DJ Frankie Knuckles, DJ Kip Lavinger, DJ Zoe B, the Lady Bunny, and Dean Johnson, whose Tuesday night "Rock and Roll Fag Bar" party gave rise to New York's gay rock and roll scene. Several big-name music acts also made cameo appearances at The World, including David Bowie, the Beastie Boys, The Ramones, Echo & the Bunnymen, Madness, Big Audio Dynamite, Sinéad O'Connor, Public Enemy, Neil Young, The Sugarcubes, Salt-N-Pepa, and Pink Floyd. The World was also used as one of the filming locations for Devo's 1988 music video for the song "Disco Dancer" The World operated largely outside the law, and opened and closed unpredictably. It ceased operations permanently in 1991, when its owner was found dead on the premises. The building that housed The World was subsequently demolished and replaced with an apartment building.

Slugs' Saloon was a jazz club at 242 East 3rd Street, between Avenue B and C in Manhattan's East Village, operating from the mid-1960s to 1972. The location, in what was then a run-down part of New York City, first hosted a Ukrainian restaurant and bar, and later a bar that served as a meeting point for drug dealers. In 1964, Robert Schoenholt and Jerry Schultz opened it as a club and initially called it "Slugs' Saloon", the "slugs" being a reference to the "three-centered beings" and "terrestrial three-brained beings" mentioned in the book Beelzebub's Tales to His Grandson by George Gurdjieff. Due to New York City regulations, the word "saloon" had to be dropped from the name. The venue was called "Slugs' in the Far East", due to its easterly location in the East Village. The interior of the club was longer than it was wide and the bandstand all the way in the back. It could fit 75 people but often held twice that. The bar was on the left side as one entered the venue. The wooden sign that hung outside the venue was carved by James Jackson. During the mid-1960s it slowly started attracting regular jazz performances, developing a reputation as a musician's bar. In this period it became closely associated with free-jazz musician Sun Ra: from March 1966 through late 1967, Sun Ra and his Arkestra (billed as "Sun Ra and His Astro-Infinity Music") played regular gigs every Monday, and continued to play the venue irregularly thereafter. By the late 1960s the club had grown a vibrant scene in its out-of-the-way location, with performances from prominent jazz musicians including Sonny Rollins, Albert Ayler and Ornette Coleman, among many others. Some of these performances were recorded, often surreptitiously, and appear on officially released or on bootleg albums. Audiences included a number of well-known artists and musicians, ranging from Larry Rivers to Paul H. Brown to Bob Thompson and Salvador Dalí. The venue saw the death of Lee Morgan on February 19, 1972, when he was shot at the bar by his common-law wife Helen Moore. The general demise of the neighborhood and his hard lifestyle as a club owner led Jerry Schulz to leave, and the club shut down in late 1972.

Hamilton Fish Park is a public park in the Lower East Side neighborhood of Manhattan in New York City. The park encompasses two blocks bounded by Houston, Pitt, Sheriff, and Stanton Streets. It contains a playground, basketball courts, and an outdoor swimming complex with general swimming and wading pools. Hamilton Fish Park also includes a Beaux-Arts recreation center designed by Carrère and Hastings. It is maintained by the New York City Department of Parks and Recreation (NYC Parks). Hamilton Fish Park, named after former New York governor Hamilton Fish, was planned during the late 19th century to alleviate overcrowded living conditions in the Lower East Side. The park and recreation building opened in 1900 as a landscaped park designed by Carrère and Hastings. The original design was reconfigured to accommodate more active recreation uses. The pool was built during a Works Progress Administration project in 1935–1936. The recreation center was made a New York City designated landmark in 1982, and the park was restored in the 1990s.