St. Joseph's Hospital Health Center (Syracuse, New York)

St. Joseph's Health is a not-for-profit hospital network in upstate New York. It is anchored by St. Joseph's Hospital is a 451-bed medical facility in Syracuse. The hospital is one of a growing number with "a separate psychiatric emergency department;" theirs has 10 beds and it opened in 2007.

The Louis Will House is a "high-style" Queen Anne style house at 714 N. McBride St. in Syracuse, New York. It was listed on the National Register of Historic Places on November 10, 2009. It was the home of Louis Will, Progressive Party mayor of Syracuse during 1914–16. He was owner of a candle-making business.The exterior of the house is built of brick on a sandstone foundation. Terra-cotta features decorate various parts of the house. A porch with turned wood elements wraps from the west facing front of the house around the south side. The most significant feature of the house is its stained glass windows, which are believed to be early works of the Tiffany studios in New York City. Oddly, the architect is unknown, despite original plans for the house being available. It faces on McBride Park and stands out as the pre-eminent home of the area.

The Church of St. John the Evangelist was a church in the Roman Catholic Diocese of Syracuse on 215 North State Street from 1855 to its closure in June 2010. Since 2014 the church building has housed the Samaritan Center, Syracuse's largest soup kitchen.

The Church of the Saviour (Syracuse) is a chapel in the Episcopal Diocese of Central New York. It is an Anglo-Catholic Episcopal parish noteworthy for its historically significant architecture and decor, which took shape in the late nineteenth and early twentieth centuries. The Church of the Saviour was first organized in Syracuse, New York in 1848 as St. James Church. It was only the second church established in the state of New York to have entirely free pews. After a series of fires, the building was replaced in 1891 with one designed by Syracuse architect Asa L. Merrick. Seven years later, after a bankruptcy auction, the parish was reorganized as the Church of the Saviour. Finally, after yet another fire, in 1912, the building interior was redesigned by the firm of Ralph Adams Cram, one the country's leading exponents of Gothic Revival architecture and proponent of Anglo-Catholic worship. The interior of the Church of the Saviour features a rood beam carved in 1913 by Johannes Kirchmayer of Boston; an altar of Caen stone and Carrara marble, by the firm of J. and R. Lamb, dedicated in 1915; and a 2,000-pipe organ built by the M. P. Möller Company in 1962. The organ was built according to an unusual design created by the musicologist Ernest F. White, the Möller Company's tonal director, who also served as the Church of the Saviour's organist and musical director in 1962–1963. The building also contains a lady chapel and a wooden columbarium. Sunday Eucharistic services at the Church of the Saviour are conducted according to rite I of the Book of Common Prayer, similar to the form of the liturgy used in Episcopal churches in the United States before 1979.

Odd Fellows Lodge and Temple, also known as the Lincoln Lodge, is a historic Odd Fellows Lodge located near Downtown Syracuse, Onondaga County, New York. It was built in 1887, and is a three-story, Romanesque Revival style brick building. It features decorative brickwork and was expanded before 1892. It housed a public library on the first floor, lodge related dwellings on the second floor, and the Odd Fellows meeting hall on the third. It was originally a German-speaking Lodge and vacated the building in 1945.: 5 It was listed on the National Register of Historic Places in 2014.

First English Lutheran Church was founded in 1879 Syracuse, New York. The building was designed by Archimedes Russell and built in 1911. It is significant for its mission-inspired architecture. The church's mission statement says that it is "a safe, spiritual haven for sharing the truth and love of the gospel of Jesus Christ" and that they "welcome all people regardless of race, creed, color or sexual orientation for worship and community services," that they "respect the needs of a changing world, maintain a history of our Lutheran roots and heritage, recognize our God given talents, especially the gift of music, grow as we reach out to serve our neighbors, friends of FEL, as well as each other," and that they "hope, trust and pray that we might fulfill God's mission to share our many blessings."The building was added to the National Register of Historic Places in 1998.

Little Italy Syracuse is an ethnic enclave in Syracuse, New York that contains several bakeries, cafés, pizzerias, restaurants, beauty salons, shops, bars and nightclubs. The main street in the neighborhood is North Salina Street. Italian immigrants began to settle in the Northside of Syracuse in the early 1880s, however, the neighborhood was not officially designated as Little Italy until 2003.

The Third National Bank, also known as the Community Chest Building, is located on James Street in Syracuse, New York. It was designed by architect Archimedes Russell in 1885. It is significant for its architecture and for its role in commerce in Syracuse in the late eighteenth century. It was added to the National Register of Historic Places in 1972.

The Erie Canal Museum is a historical museum about the Erie Canal located in Syracuse, New York. The museum was founded in 1962 and is a private, non-profit corporation. It is housed in the Syracuse Weighlock Building dating from 1850. The Syracuse Weighlock Building was in operation as a weighlock from 1850 to 1883. In 1883 the canal decided to stop charging tolls. The weighlock building was essentially used as a big, elaborate scale to weigh the boats traveling on the Erie Canal and determine how much each boat would pay for a toll. Today the museum includes not only artifacts from the Erie Canal, but also a gallery of present canal life. It is the mission of the museum to help people to learn the rich history of the Erie Canal and that it is not just a thing of the past, but still very much exists today in different forms. The museum's Weighlock Building was listed on the National Register of Historic Places in 1971.

Syracuse Savings Bank Building, also known as Bank of America building, is a historic building in Syracuse, New York designed by Joseph Lyman Silsbee. It was built in 1875 adjacent to the Erie Canal, and, at 170 feet tall, was the tallest building in Syracuse. It opened in 1876 as Syracuse Savings Bank. Its passenger elevator, the first in Syracuse, was a curiosity that drew visitors.

Leavenworth Apartments is a historic apartment building located in the Near Northeast neighborhood of Syracuse, Onondaga County, New York. It was designed by architect Charles Erastus Colton and built in 1912. It is a seven-story, Colonial Revival style asymmetrical building in six sections. It is a steel frame and masonry building with cast stone details. The building features stepped gable ends. It is located across from the New Kasson Apartments built in 1898.: 3 It was listed on the National Register of Historic Places in 2011.

Jill-Lyn Euto (March 20, 1982 – January 28, 2001) was an American woman who was found murdered in her apartment in Syracuse, New York, in 2001. Euto had made plans with her mother and sister to watch Super Bowl XXXV at their house elsewhere in the city. When Euto did not show up at their house or respond to phone calls the next day, her mother and sister went to her apartment, where they found her stabbed to death with a knife from her own kitchen. The murder remains unsolved. While suspects have been considered and surveilled by police, no one has ever been publicly named by authorities.