Center for Italian Modern Art

Soho Synagogue was a "hipster" synagogue located in the SoHo neighborhood of Manhattan, New York. On September 15, 2009, The SoHo Synagogue signed a 7-year lease for the ground floor of 43 Crosby Street, located between Spring and Broome Streets. Designer Dror Benshetrit designed the synagogue space.The SoHo Synagogue was founded in 2005 by Chabad-Lubavitch Rabbi Dovi Scheiner and his wife Esty.

The E.V. Haughwout Building is a five-story, 79-foot (24 m) tall commercial loft building in the SoHo neighborhood of Manhattan, New York City, at the corner of Broome Street and Broadway. Built in 1857 to a design by John P. Gaynor, with cast-iron facades for two street-fronts provided by Daniel D. Badger's Architectural Iron Works, it originally housed Eder V. Haughwout's fashionable emporium, which sold imported cut glass and silverware as well as its own handpainted china and fine chandeliers, and which attracted many wealthy clients – including Mary Todd Lincoln, who had new official White House china painted here. It was also the location of the world's first successful passenger elevator.

The Museum of Women is scheduled to open in a five floor building that was formerly home to Topshop at 480 Broadway in SoHo in the summer of 2022. The museum was founded by Abby Trott and will offer interactive exhibits and a gift shop featuring products made by women. Its physical location is expected to run through the end of 2022 at least and will explore issues faced by women in contemporary society and culture.

Mechanics' Hall was a meeting hall and theatre seating 2,500 people located at 472 Broadway in New York City, United States. It had a brown façade. Built by the Mechanics' Society for their monthly meetings in 1847, it was also used for banquets, luncheons, and speeches held by other groups. The building eventually became a playhouse. During this time, it was variously known as the Abbey Theatre, Butler's American Theatre, and other names. The blackface minstrel troupe Buckley's Serenaders saw great success there until 1846. Christy's Minstrels became the resident minstrel company in February 1847, buying the building later in 1847. They remained until July 1854, when the troupe disbanded. Bryants Minstrels played at Mechanics' Hall for the first time in 1857, leaving after May, 1866, when the house was taken over for a season by minstrel showman Charles "Charlie" White.In 1867, showman Robert Butler took over management of Mechanics' Hall following a fire that destroyed his former theater at 444 Broadway. Butler's luck was no better in the new venue as Mechanics' Hall was also destroyed by fire later that year.

Environ was a performance space that was influential during the Loft Jazz scene of the mid-1970s in NYC. It was located on Broadway in SOHO and close to two other noted Loft Jazz venues: RivBea and Ali's Alley. Environ was established by Chris Brubeck and Danny Brubeck sons and band mates of noted jazz musician Dave Brubeck. Environ was managed by John Fischer pianist leader of Interface with assistance by staff Mark Forman indie media producer and Brian Olewnick music blogger and reviewer for Bagatellen. Environ offered performance space to many Loft Jazz musicians, dancers and other performance artists. Dave Holland (former Miles Davis bassist), Anthony Braxton, Charles Tyler, Hamiet Bluiett, David Murray, Lester Bowie, Joseph Bowie, Chico Freeman were some of the many free jazz artists that performed there. James Siegfried, who was later to become better known as James Chance, and the Contortions (part of the No Wave scene in NYC) had his debut there. Environ attracted many of the future avant-garde jazz and No Wave musicians to its stage and audience. Muhal Richard Abrams one of the founders of the AACM practiced there regularly on the house piano.

240 Centre Street, formerly the New York City Police Headquarters, is a building between Broome and Grand Streets in the Nolita neighborhood of Manhattan, New York City.

The New Era Building is an 1893 Art Nouveau commercial loft building at 495 Broadway, between Spring Street and Broome Street, in the SoHo section of Manhattan in New York City.

Lieutenant Joseph Petrosino Square is small triangular park in lower Manhattan in New York City, bounded by Cleveland Place and Lafayette and Kenmare Streets, two blocks north of the old police headquarters at 240 Centre Street, at the juncture of the Little Italy, Nolita, and SoHo neighborhoods. Formerly Kenmare Square, it changed its name in 1987 in honor of Lieutenant Joseph Petrosino, an early 20th century NYPD official dedicated to investigating and combating, among other adversaries, the Black Hand, an early version of the Mafia in America. The park underwent a $2 million renovation in 2008–2011, and is the site of a controversial CitiBike docking station.

The Theatre Comique, formerly Wood's Minstrel Hall, was a venue on Broadway in Manhattan, New York City. It was built in 1862, replacing a synagogue on the site.

Yellow Rat Bastard is the flagship establishment in a chain of New York City retail clothing stores and print magazine owned by Henry Ishay. It specializes in hip hop and alternative-style clothing and shoes.

The St. Nicholas Hotel was a 600-room, mid-nineteenth century luxury hotel on Broadway in the neighborhood of SoHo in Manhattan, New York City. It opened on January 6, 1853, and by the end of the year had expanded to 1,000 rooms. The St. Nicholas raised the bar for a new standard of lavish appointments for a luxury hotel. It was the first New York City building to cost over US$1 million. The hotel was said to have ended the Astor House's preeminence in New York hostelry.

The International Culinary Center was a private for-profit culinary school headquartered in New York City. In 2020, it merged into the Institute of Culinary Education, also in New York City. It was founded as The French Culinary Institute by Dorothy Cann Hamilton in 1984 and has campuses in New York City and the San Francisco Bay Area. The facilities include professional kitchens for hands-on cooking and baking classes, specialized wine tasting classrooms, a library, theater, and event spaces.