Statue of Christopher Columbus (Wilkes-Barre, Pennsylvania)

St. Stephen's Episcopal Pro-Cathedral is an Episcopal church located in Wilkes-Barre, Luzerne County, Pennsylvania. It is the Pro-Cathedral in the Diocese of Bethlehem. The Cathedral Church of the Nativity in Bethlehem, Pennsylvania serves as the primary cathedral of the diocese. St. Stephen's Church began in 1817. The present church building is the fifth one for the parish. It was completed in 1897 and consecrated in 1899. Philadelphia architect Charles M. Burns designed the church in the Romanesque Revival style.

The Luzerne County Historical Society is one of the oldest continually operating local historical societies in America. It was founded on February 11, 1858, in recognition of the 50th anniversary of the first successful burning of anthracite coal by Jesse Fell, and was originally named the Wyoming Historical and Geological Society. The organization operates the historic Swetland Homestead in Wyoming, Pennsylvania and the Luzerne County Museum which also features a separate research library in Wilkes-Barre, Pennsylvania. It also administers the Nathan Denison house.

The Luzerne County Library System (LCLS) is an organization that administers ten libraries in Luzerne County, Pennsylvania. Founded in 1984, it is headquartered at the Osterhout Free Library in Wilkes-Barre, Pennsylvania. Along with hosting various permanent and temporary collections of books and media, the member libraries provide various services and activities.

There is a different Westmoreland Club in Richmond, VirginiaThe Westmoreland Club is a private social club that was established in 1873 in Wilkes-Barre, Pennsylvania. Members are Northeastern Pennsylvania "leaders in the arts, business, education, government, and industry”.

Hotel Sterling was a hotel in downtown Wilkes-Barre, Pennsylvania, at the intersection of River Street and Market Street. It was opened in 1898 by local businesspeople, who then owned a music hall located at the site, and was named after Emma E. Sterling, whose late husband, Walter G. Sterling, a local banker and businessman, owned a share of the music hall. Emma was a driving force behind the building of the hotel. The hotel was later expanded by Andrew Sordoni by connecting it to the Plaza Hotel in 1936. After lying abandoned for years, the non-profit organization CityVest purchased the hotel and demolished the 14-story Plaza tower portion and four-story connecting building in 2007 in an attempt to make the property more marketable to developers. Demolition of the original 1897-built building began on July 25, 2013 and finished on July 30, 2013.

James Buchanan High School is a small, rural public high school. The school is located in Mercersburg, Pennsylvania and is part of the Tuscarora School District. James Buchanan High School was named after the 15th president of the United States, James Buchanan. In 2013, enrollment was reported as 785 pupils in 9th through 12th grades. The school employed 48 teachers.

McClintock Hall, also known as McClintock House, is an historic, American dormitory that is located on the campus of Wilkes University in Wilkes-Barre, Luzerne County, Pennsylvania. It was added to the National Register of Historic Places in 1972.

James M. Coughlin High School was an urban school located in Wilkes-Barre, Pennsylvania. It served grades 9-12 in the Wilkes-Barre Area School District.

The River Street Historic District is a national historic district that is located in Wilkes-Barre, Pennsylvania. It was added to the National Register of Historic Places in 1985.

The Market Street Bridge is a distinguished concrete arch bridge that crosses the Susquehanna River between Kingston and Wilkes-Barre, Luzerne County, Pennsylvania. It was listed on the National Register of Historic Places in 1988.

Catlin Hall, also known as George Catlin Hall and Reynolds House, is a historic dormitory located on the campus of Wilkes University at Wilkes-Barre, Luzerne County, Pennsylvania. It was built in 1843, and is a 2 1/2-story, rectangular brick building in the Greek Revival style. It has a two-story rear wing. It was built as the Reynolds family residence and used as such into the 1950s, after which it was sold to Wilkes College in 1957. It was used as the women's residence hall and named for Wilkes-Barre native, painter George Catlin.It was added to the National Register of Historic Places in 1972.

Wilkes-Barre ( WILKS-bair or -⁠bair-ee) is a city in and the county seat of Luzerne County, Pennsylvania, United States. Located at the center of the Wyoming Valley in Northeastern Pennsylvania, it had a population of 44,328 in the 2020 census. It is the second-largest city, after Scranton, in the Scranton–Wilkes-Barre–Hazleton, PA Metropolitan Statistical Area, which had a population of 567,559 as of the 2020 census, making it the fifth-largest metropolitan area in Pennsylvania after the Delaware Valley, Greater Pittsburgh, the Lehigh Valley, and Greater Harrisburg.The contiguous network of five cities and more than 40 boroughs all built in a straight line in Northeastern Pennsylvania's urban core act culturally and logistically as one continuous city, so while the city of Wilkes-Barre itself is a mid-sized city, the larger Scranton/Wilkes-Barre Urban Area contains half a million residents in roughly 300 square miles (780 km2). Scranton/Wilkes-Barre is the cultural and economic center of a region called Northeastern Pennsylvania, which is home to over 1.3 million residents. Wilkes-Barre and the surrounding Wyoming Valley are framed by the Pocono Mountains to the east, the Endless Mountains to the north and west, and the Lehigh Valley to the south. The Susquehanna River flows through the center of the valley and defines the northwestern border of the city. Wilkes-Barre was founded in 1769, incorporated as a borough in 1806, and formally re-incorporated as a city in 1869. The city grew rapidly in the 19th century after the discovery of nearby coal reserves and the arrival of hundreds of thousands of immigrants, who provided a labor force for the city's mines. The mining of high-quality anthracite coal fueled industrialization in the city, which reached the height of its prosperity in the first half of the 20th century. Its population peaked at more than 86,000 in 1930. Following World War II, the city's economy declined due to the collapse of industry. The Knox Mine disaster accelerated this trend after large portions of the area's coal mines were flooded and could not be reopened. In the 21st century, the city's population is roughly half that of its peak population of the 1930s, though it remains the largest city in Luzerne County and the 13th-largest city in Pennsylvania. Wilkes-Barre is located approximately 63 miles (101 km) northwest of Allentown, and 113 miles (182 km) northwest of Philadelphia.