Manhattan Center for Science and Mathematics

The Pontifical shrine of Our Lady of Mount Carmel is a Roman Catholic parish church under the authority of the Archdiocese of New York, located in East Harlem, Manhattan, New York City, United States. The church's formal address is 448 East 116th Street, although the entrance to the church building is on East 115th Street, just off Pleasant Avenue. The parish enshrines a vested statue of the Blessed Virgin Mary under the title of Our Lady of Mount Carmel, widely venerated by its devotees. Pope Leo XIII granted the image a Pontifical decree of Canonical Coronation on 12 May 1903. Pope Pius X carried over the Pontifical decree and donated a gemstone for the crown to which the rite of coronation was executed on 10 July 1904.

Rao's () is a Southern Italian restaurant founded in 1896. It is located at 455 East 114th Street, on the corner of Pleasant Avenue in East Harlem, New York City. Rao's has sister restaurants in Los Angeles and Las Vegas, Nevada.

Thomas Jefferson Park is a 15.52-acre (6.28 ha) public park in the East Harlem neighborhood of Manhattan in New York City. The park is on First Avenue between 111th and 114th Streets. It contains a playground as well as facilities for baseball, basketball, football, handball, running, skating, and soccer. The Thomas Jefferson Play Center within the park consists of a recreation center and a pool. The park and play center, named for former U.S. president Thomas Jefferson, are maintained by the New York City Department of Parks and Recreation (NYC Parks). The land for the park was acquired starting in 1897. Though the park opened in 1902, the first recreational facilities did not open until 1905. The pool and bathhouse was designed by Stanley C. Brogren during a Works Progress Administration project in 1935–1936, while a playground next to the adjacent Benjamin Franklin High School opened in 1942. The pool was extensively refurbished in 1992, followed by the park in 1994. The Thomas Jefferson Play Center was designated a city landmark by the New York City Landmarks Preservation Commission in 2007.

East River Plaza is a shopping mall located at FDR Drive near the Harlem River between 116th and 119th Street in East Harlem, New York City. Opened on November 12, 2009, after a protracted development process lasting 15 years, the mall has twelve stores with four anchor stores, which are Target, Costco, Burlington Coat Factory, and PetSmart. It has six levels and is attached to a parking garage.

The Young Women's Leadership School of East Harlem (TYWLS) is a public all-girls school in East Harlem, Manhattan, New York City. The school serves approximately 440 young women in 6th through 12th grade. It is part of the Young Women's Leadership Network (YWLN). It was founded in 1996 by Ann and Andrew Tisch and New York City's Center for Education Innovation Public Education Association. They believed that it would help school families because in other public schools many girls weren't heard and the graduation rates were low. Then-Chancellor Rudy Crew led the project to the unanimous support of the New York City Board of Education.

The Church of the Holy Rosary was a Roman Catholic parish church under the authority of the Roman Catholic Archdiocese of New York, located at 444 East 119th Street, East Harlem, Manhattan, New York City. In November 2014, the Archdiocese announced that the Church of the Holy Rosary was one of 31 neighborhood parishes which would be merged into other parishes. Holy Rosary was merged into the Church of St. Paul at 113 East 117th Street.The church was deconsecrated on June 30, 2017.

Patsy's Pizzeria is a historic coal-oven pizzeria in New York City. Opened in 1933, it was regarded as one of New York's original pizzerias for its use of traditional New York style thin crust pizza.

The 117th Street station was a local station on the demolished IRT Second Avenue Line in Manhattan, New York City. It had three tracks and two side platforms. The next stop to the north was 121st Street. The next stop to the south was 111th Street. The station closed on June 11, 1940.

The 1199 Plaza is a housing project in East Harlem. Located on First Avenue, on the western bank of the East River, the 1199 Plaza consists of four 31-story towers, joined by mid-rise units which extend toward the riverbank. 1199 Plaza opened in 1974, as a low-to-middle income housing project. The 1199 Plaza traces its origin to the 1199 union, which consisted mainly of female lower-income hospital workers. The 1199 union members wanted housing that was safe, affordable, and socially inclusive. Hodne/Stageberg Partners, Inc served as the architects of the project, while Ruberoid supplied building materials. In the 1990s, the 1199 Plaza began offering housing for non-HUD applicants. A new title, East River Landing, was adopted. The 1199 Plaza has thus become a hybrid project, housing both middle-income and higher-income applicants, in addition to poorer residents. The 1199 Plaza has been described as a "city within a city", owing to its sheer scale and unique design.

116th Street is a planned station along the IND Second Avenue Line of the New York City Subway. It would be located at the intersection of Second Avenue and 116th Street in East Harlem, Manhattan. Proposed since 1968, the station is expected to be built as part of Phase 2 of the Second Avenue Subway. When opened, it will initially be served by the Q train, with the T train providing service when Phase 3 of the line is built.

Kirby Forensic Psychiatric Center is a maximum-security facility for the mentally ill on Wards Island in New York City, operated by the New York State Office of Mental Health as one of two psychiatric hospitals in the state that treat felony patients. The building, described as "fortresslike", is adjacent to the Manhattan Psychiatric Center. Of its more than 200 patients, 50 are deemed criminally insane; it houses pre-trial detainees unfit to stand trial as well as convicted defendants granted an insanity plea. Among its famous historical inmates was murderer and cannibal Daniel Rakowitz.

The Manhattan Psychiatric Center is a New York-state run psychiatric hospital on Wards Island in New York City. As of 2009, it was licensed for 509 beds, but holds only around 200 patients. The current building is 17 stories tall. The building strongly resembles the main building of the Creedmoor Psychiatric Center in Queens. It is adjacent to Kirby Forensic Psychiatric Center, a specialized facility for patients with criminal convictions.