Sioux City Central High School and Central Annex

The First Congregational Church, also known as Iglesia Pentecostes Evangelica Principe de Paz, is a house of worship located in Sioux City, Iowa, United States. An architectural rarity, it is one of a small group of churches in the Prairie School style of architecture. Designed primarily in the Prairie style with some eclectic touches by architect William L. Steele, its horizontal lines are emphasized by Roman brick and crisp rectilinear forms. Somewhat at variance are the distinctive dome and the prominent round heads on the windows. Fresh from his triumph with the Woodbury County Courthouse in collaboration with George Grant Elmslie, and drawing on lessons learned during that collaboration, Steele built the church in 1916–1918. This church and the courthouse are the only two Prairie style buildings that are known to have a dome. It was built for a Congregational church that had been established in Sioux City back in 1857, replacing a more traditional church that had burned down in 1916. In 1966, that congregation built a new structure on Hamilton Boulevard. First Congregational Church sold the building to Sioux City Baptist Church c. 1968. It was listed on the National Register of Historic Places in 1979 under that name. In 2009, Sioux City Baptist Church acquired a building on Viking Drive. Most recently, the building has become the Iglesia Evangelica Pentecostes Principe de Paz (Evangelical Pentecostal Church of the Prince of Peace), with services in Spanish aimed at the local Hispanic community. Due to the need for extensive building restoration and maintenance, the structure has been named to endangered building lists by at least two historic preservation groups.

Mount Sinai Temple is an historic former Reform synagogue located in Sioux City, Iowa, in the United States. The building was listed on the National Register of Historic Places in 1999.

Ye Olde Tavern was a restaurant that specialized in tavern sandwiches located at the corner of 14th and Jackson streets in Sioux City, Iowa. The establishment was founded by John David ("Dave") Heglin, who is credited as one of the creators of the tavern sandwich.

St. Thomas Orthodox Church in Sioux City, Iowa is a parish of the Great Plains Deanery of the Diocese of Wichita and Mid-America, part of the Antiochian Orthodox Christian Archdiocese of North America, a constituent archdiocese of the Greek Orthodox Patriarchate of Antioch and All the East. Founded in 1916 to serve the Syrian and Lebanese immigrant community that existed in Sioux City at that time,: 114  it is the oldest Orthodox parish in Sioux City and has become a pan-Orthodox community with members from across the Siouxland region.

St. Thomas Episcopal Church is a parish church in the Episcopal Diocese of Iowa. The church is located in Sioux City, Iowa, United States. The church building was listed on the National Register of Historic Places in 1984.

The Sioux City Masonic Temple in Sioux City, Iowa was built during 1921–1922. It was listed on the National Register of Historic Places in 2004. It is a two and a half or three story building that cost nearly $300,000 to build, not including nearly $200,000 of custom furnishings. In 2004 it was deemed significant as "an excellent, unaltered example of the Spanish Colonial Revival architectural design"; it was one of only two downtown commercial buildings in that style, which was popular during 1915 to 1940. The other is the NRHP-listed Sioux City Free Public Library, two blocks south. It was designed by Sioux City architects Beuttler and Arnold.: 8 

The Sioux City metropolitan statistical area, as defined by the United States Census Bureau, is an area consisting of four counties in three states – Iowa, Nebraska, and South Dakota, anchored by the city of Sioux City, Iowa. As of the 2020 census, the MSA had a population of 145,940. Plymouth County, Iowa, was removed from the definition of the MSA prior to the 2020 census.

The Diocese of Sioux City (Latin: Diœcesis Siopolitanensis) is the Latin Church diocese for the northwestern quarter of the state of Iowa in the United States. It is a suffragan see of the Archdiocese of Dubuque. The cathedral parish for this diocese is the Epiphany and the see city is Sioux City. The Diocese of Sioux City comprises 24 counties in northwestern Iowa, covering 14,518 square miles (37,600 km2). Reverend R. Walker Nickless was ordained as bishop of Sioux City on January 20, 2006.

The Cathedral of the Epiphany is a cathedral and a parish church located in Sioux City, Iowa, United States. It is the seat of the Diocese of Sioux City.

ACME Comics & Collectibles is a comics and collectibles store in Sioux City, Iowa. The store was awarded the 2004 "Spirit of Comics Retailer Award" at the Eisner Awards.

The Alhambra Apartments is a historic building located in Sioux City, Iowa, United States. The city experienced a building boom in 1929, and this building was constructed at that time by American Builders Incorporated of Lincoln, Nebraska. It was one of five apartment buildings built in the city that year, and based on the cost of construction it was the largest. The six-story U-shaped building rests on top of an underground parking garage. The residents could access the garage by way of an elevator. The building is composed of reinforced concrete faced with tan brick and terra cotta trim. Its design is an eclectic mix of architectural styles with Moorish influences. The Alhambra is located in a residential called the Near North-Side, just outside of the central business district. It was listed on the National Register of Historic Places in 2001.

The Elzy G. Burkam House is a historic house located in Sioux City, Iowa, United States. Built in 1894, it is an example of a transitional house between the revival styles popular in the 19th century and the Colonial Revival style that became popular in the early 20th century. The 2½-story brick and frame house was designed by Sioux City architect William D. McLaughlin. Its asymmetrical form was more common in the Colonial Revival style in the 1890s than it was after 1900. The house features round arch windows from the Romanesque Revival style, deep eaves with exposed rafters from the Stick Style, and it is capped with a hip roof with a dormer. The exterior of the first is covered with brick, while the second floor is covered with Clapboard. A conservatory dominates the south elevation. The house was individually listed on the National Register of Historic Places in 1998,. In 2005 it was included as a contributing property in the Rose Hill Historic District in 2005.